Berberine therapy of hypertyraminemia in patients with liver cirrhosis.

plasma tyramine concentrations ewre abnormally high in cirrhotic patients with hepatic encephalopathy. Oral administration of berberine hydrochloride corrected hyperyraminemia in cirrhotics and also prevented the elevation of plasma tyramine levels following the oral tyrosine load, probably because of berberine-inhibition of bacterial tyrosine decarboxylase in the intestine. This is a new approach as Anti-amine therapy for cirrhotic patients