Acquired dependence of acute myeloid leukemia on the DEAD-box RNA helicase DDX5.
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S. Lowe | B. Stillman | J. Gillis | Youngkyu Park | J. Wilkinson | C. Miething | C. Vakoc | A. Mazurek | J. Wilkinson
[1] H. Shen,et al. DDX5 is a positive regulator of oncogenic NOTCH1 signaling in T cell acute lymphoblastic leukemia , 2013, Oncogene.
[2] F. Fuller-Pace. The DEAD box proteins DDX5 (p68) and DDX17 (p72): multi-tasking transcriptional regulators. , 2013, Biochimica et biophysica acta.
[3] S. Kornbluth,et al. The tangled circuitry of metabolism and apoptosis. , 2013, Molecular cell.
[4] F. Fuller-Pace,et al. The RNA helicase p68 (DDX5) is selectively required for the induction of p53-dependent p21 expression and cell cycle arrest after DNA damage , 2012, Oncogene.
[5] M. Lacroix-Triki,et al. Splicing switch of an epigenetic regulator by RNA helicases promotes tumor-cell invasiveness , 2012, Nature Structural &Molecular Biology.
[6] Bruce Stillman,et al. DDX5 regulates DNA replication and is required for cell proliferation in a subset of breast cancer cells. , 2012, Cancer discovery.
[7] T. Naoe,et al. Acute myeloid leukemia in older adults , 2012, International Journal of Hematology.
[8] Christof Fellmann,et al. A pipeline for the generation of shRNA transgenic mice , 2012, Nature Protocols.
[9] A. Scorilas,et al. The Role of BCL2 Family of Apoptosis Regulator Proteins in Acute and Chronic Leukemias , 2011, Advances in hematology.
[10] Jianbo Wang,et al. RNA helicase DDX5 is a p53-independent target of ARF that participates in ribosome biogenesis. , 2011, Cancer research.
[11] S. Lowe,et al. RNAi screen identifies Brd4 as a therapeutic target in acute myeloid leukaemia , 2011, Nature.
[12] S. Robson,et al. Inhibition of BET recruitment to chromatin as an effective treatment for MLL-fusion leukaemia , 2011, Nature.
[13] T. Graeber,et al. An integrated approach to dissecting oncogene addiction implicates a Myb-coordinated self-renewal program as essential for leukemia maintenance. , 2011, Genes & development.
[14] Paul Pavlidis,et al. The role of indirect connections in gene networks in predicting function , 2011, Bioinform..
[15] S. Lowe,et al. Reversible suppression of an essential gene in adult mice using transgenic RNA interference , 2011, Proceedings of the National Academy of Sciences.
[16] Jesse Gillis,et al. Gene function analysis in complex data sets using ErmineJ , 2010, Nature Protocols.
[17] Philippe Dessen,et al. Targeting iron homeostasis induces cellular differentiation and synergizes with differentiating agents in acute myeloid leukemia , 2010, The Journal of experimental medicine.
[18] Simak Ali,et al. The DEAD box protein p72 regulates ERα-/Estrogen-dependent transcription and cell growth, and is associated with improved survival in ERα positive breast cancer , 2009, Oncogene.
[19] A. Üren,et al. Small molecule selected to disrupt oncogenic protein EWS-FLI1 interaction with RNA Helicase A inhibits Ewing's Sarcoma , 2009, Nature Medicine.
[20] R. Cencic,et al. Antitumor Activity and Mechanism of Action of the Cyclopenta[b]benzofuran, Silvestrol , 2009, PloS one.
[21] J. Downing,et al. Mouse models of human AML accurately predict chemotherapy response. , 2009, Genes & development.
[22] F. Fuller-Pace,et al. The RNA helicase p68 is a novel androgen receptor coactivator involved in splicing and is overexpressed in prostate cancer. , 2008, Cancer research.
[23] J. Grande,et al. Involvement of RNA helicases p68 and p72 in colon cancer. , 2007, Cancer research.
[24] H. Uhlmann-Schiffler,et al. Redundant role of DEAD box proteins p68 (Ddx5) and p72/p82 (Ddx17) in ribosome biogenesis and cell proliferation , 2007, Nucleic acids research.
[25] B. O’Malley,et al. DEAD-box RNA helicase subunits of the Drosha complex are required for processing of rRNA and a subset of microRNAs , 2007, Nature Cell Biology.
[26] Hartmut Döhner,et al. Acute myeloid leukaemia , 2006, The Lancet.
[27] Rudolf Jaenisch,et al. Efficient method to generate single‐copy transgenic mice by site‐specific integration in embryonic stem cells , 2006, Genesis.
[28] S. Cory,et al. Killing cancer cells by flipping the Bcl-2/Bax switch. , 2005, Cancer cell.
[29] S. Korsmeyer,et al. An inhibitor of Bcl-2 family proteins induces regression of solid tumours , 2005, Nature.
[30] W. Hiddemann,et al. AML with 11q23/MLL abnormalities as defined by the WHO classification: incidence, partner chromosomes, FAB subtype, age distribution, and prognostic impact in an unselected series of 1897 cytogenetically analyzed AML cases. , 2003, Blood.
[31] F. Fuller-Pace,et al. Overexpression and poly-ubiquitylation of the DEAD-box RNA helicase p68 in colorectal tumours , 2001, Oncogene.