Phenethyl isothiocyanate and sulforaphane and their N-acetylcysteine conjugates inhibit malignant progression of lung adenomas induced by tobacco carcinogens in A/J mice.
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S. Hecht | Chung-Xiou Wang | B. Pittman | F. Chung | Yang-ming Yang | D. Tian | E. McIntee | C. Conaway | J. Schwartz | Joel Schwartz | S. Hecht | F. Chung | Chung Xiou Wang | Yang Ming Yang | Joel E. Schwartz
[1] F. Traganos,et al. N-acetylcysteine conjugate of phenethyl isothiocyanate enhances apoptosis in growth-stimulated human lung cells. , 2005, Cancer research.
[2] P. Karplus,et al. A Novel Mechanism of Chemoprotection by Sulforaphane , 2004, Cancer Research.
[3] J. Pullar,et al. The chemopreventive agent phenethyl isothiocyanate sensitizes cells to Fas-mediated apoptosis. , 2003, Carcinogenesis.
[4] V. Steele,et al. Effect of chemopreventive agents on separate stages of progression of benzo[alpha]pyrene induced lung tumors in A/J mice. , 2003, Carcinogenesis.
[5] K. Singletary,et al. Sulforaphane: a naturally occurring mammary carcinoma mitotic inhibitor, which disrupts tubulin polymerization. , 2003, Carcinogenesis.
[6] H. Becher,et al. Smoking cessation and nonsmoking intervals: effect of different smoking patterns on lung cancer risk , 1991, Cancer Causes & Control.
[7] W. Guo,et al. Oral cytology assessment by flow cytometry of DNA adducts, aneuploidy, proliferation and apoptosis shows differences between smokers and non-smokers. , 2003, Oral oncology.
[8] A. Kong,et al. The roles of JNK and apoptotic signaling pathways in PEITC-mediated responses in human HT-29 colon adenocarcinoma cells. , 2003, Carcinogenesis.
[9] X. Shu,et al. Urinary isothiocyanate levels, brassica, and human breast cancer. , 2003, Cancer research.
[10] Kurt Zatloukal,et al. Automated evaluation and normalization of immunohistochemistry on tissue microarrays with a DNA microarray scanner. , 2003, BioTechniques.
[11] D. Mccrory,et al. Prevention of lung cancer: summary of published evidence. , 2003, Chest.
[12] Jian-Min Yuan,et al. Dietary isothiocyanates, glutathione S-transferase polymorphisms and colorectal cancer risk in the Singapore Chinese Health Study. , 2002, Carcinogenesis.
[13] V. Steele,et al. Prevention of mouse lung tumors by budesonide and its modulation of biomarkers. , 2002, Carcinogenesis.
[14] Shivendra V. Singh,et al. Phenethyl isothiocyanate-induced apoptosis in p53-deficient PC-3 human prostate cancer cell line is mediated by extracellular signal-regulated kinases. , 2002, Cancer research.
[15] W. Bidlack. Casarett & Doull’s Toxicology: The Basic Science of Poisons, 6th ed. , 2002 .
[16] F. Chung,et al. Isothiocyanates as cancer chemopreventive agents: their biological activities and metabolism in rodents and humans. , 2002, Current drug metabolism.
[17] T. Ahmed,et al. Sulforaphane and its metabolite mediate growth arrest and apoptosis in human prostate cancer cells. , 2002, International journal of oncology.
[18] M. Sporn,et al. Treatment and Prevention of Intraepithelial Neoplasia: An Important Target for Accelerated New Agent Development: Recommendations of the American Association for Cancer Research Task Force on the Treatment and Prevention of Intraepithelial Neoplasia , 2002 .
[19] David Harrington,et al. Comparison of four chemotherapy regimens for advanced non-small-cell lung cancer. , 2002, The New England journal of medicine.
[20] S. Amin,et al. Inhibition of benzo(a)pyrene-induced lung tumorigenesis in A/J mice by dietary N-acetylcysteine conjugates of benzyl and phenethyl isothiocyanates during the postinitiation phase is associated with activation of mitogen-activated protein kinases and p53 activity and induction of apoptosis. , 2002, Cancer research.
[21] M. Sporn,et al. Treatment and prevention of intraepithelial neoplasia: an important target for accelerated new agent development. , 2002, Clinical cancer research : an official journal of the American Association for Cancer Research.
[22] M. Teh,et al. Dietary isothiocyanates, glutathione S-transferase -M1, -T1 polymorphisms and lung cancer risk among Chinese women in Singapore. , 2001, Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology.
[23] S. Amin,et al. Decomposition rates of isothiocyanate conjugates determine their activity as inhibitors of cytochrome p450 enzymes. , 2001, Chemical research in toxicology.
[24] S. De Flora,et al. Modulation of biomarkers by chemopreventive agents in smoke-exposed rats. , 2001, Cancer research.
[25] Paul J Thornalley,et al. Signal transduction activated by the cancer chemopreventive isothiocyanates: cleavage of BID protein, tyrosine phosphorylation and activation of JNK , 2001, British Journal of Cancer.
[26] F. Chung. CHEMOPREVENTION OF LUNG CANCER BY ISOTHIOCYANATES AND THEIR CONJUGATES IN A/J MOUSE , 2001, Experimental lung research.
[27] C. Rao,et al. Chemoprevention of colonic aberrant crypt foci in Fischer rats by sulforaphane and phenethyl isothiocyanate. , 2000, Carcinogenesis.
[28] M. Spitz,et al. Dietary intake of isothiocyanates: evidence of a joint effect with glutathione S-transferase polymorphisms in lung cancer risk. , 2000, Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology.
[29] G. Coetzee,et al. Isothiocyanates, glutathione S-transferase M1 and T1 polymorphisms, and lung-cancer risk: a prospective study of men in Shanghai, China , 2000, The Lancet.
[30] D. Burns. Cigarette Smoking among the Elderly: Disease Consequences and the Benefits of Cessation , 2000, American journal of health promotion : AJHP.
[31] Pengfei Li,et al. Sulforaphane, a naturally occurring isothiocyanate, induces cell cycle arrest and apoptosis in HT29 human colon cancer cells. , 2000, Cancer research.
[32] H. Nishino,et al. Chemoprevention of lung cancer by lycopene. , 2000, BioFactors.
[33] Weiya Ma,et al. Essential role of p53 in phenethyl isothiocyanate-induced apoptosis. , 1998, Cancer research.
[34] J. Witte,et al. Glutathione transferase null genotype, broccoli, and lower prevalence of colorectal adenomas. , 1998, Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology.
[35] R. Yu,et al. Chemopreventive isothiocyanates induce apoptosis and caspase-3-like protease activity. , 1998, Cancer research.
[36] G. Yang,et al. Tea and tea polyphenols inhibit cell hyperproliferation, lung tumorigenesis, and tumor progression. , 1998, Experimental lung research.
[37] T. Baillie,et al. Biotransformation of the naturally occurring isothiocyanate sulforaphane in the rat: identification of phase I metabolites and glutathione conjugates. , 1997, Chemical research in toxicology.
[38] W. Schenk,et al. Enantioselective Organic Syntheses Using Chiral Transition‐Metal Complexes. Part 3. Synthesis of (R)‐Sulforaphane Using (CpRu((R,R)‐ CHIRAPHOS))+ as Chiral Auxiliary. , 1997 .
[39] M. Dürr,et al. Synthesis of (R)‐Sulforaphane Using [cpru(R, R)‐CHIRAPHOS)]+ as Chiral Auxiliary , 1997 .
[40] V. Steele,et al. Chemopreventive efficacy of arylalkyl isothiocyanates and N-acetylcysteine for lung tumorigenesis in Fischer rats. , 1996, Cancer research.
[41] Patrick R. Griffin,et al. Identification and inhibition of the ICE/CED-3 protease necessary for mammalian apoptosis , 1995, Nature.
[42] S. Hecht,et al. Chemoprevention by isothiocyanates , 1995, Journal of cellular biochemistry. Supplement.
[43] S. Hecht,et al. Lung tumor induction in A/J mice by the tobacco smoke carcinogens 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone and benzo[a]pyrene: a potentially useful model for evaluation of chemopreventive agents. , 1994, Carcinogenesis.
[44] Chi-Tang Ho,et al. Identification and quantification of the N-acetylcysteine conjugate of allyl isothiocyanate in human urine after ingestion of mustard. , 1994, Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology.
[45] C. S. Yang,et al. Cytochrome P-450 enzymes as targets for chemoprevention against chemical carcinogenesis and toxicity: opportunities and limitations. , 1994, Cancer research.
[46] P. Talalay,et al. Anticarcinogenic activities of organic isothiocyanates: chemistry and mechanisms. , 1994, Cancer research.
[47] M. Wong,et al. Asymmetric synthesis of chiral sulfinate esters and sulfoxides. Synthesis of sulforaphane , 1994 .
[48] S. Amin,et al. Effects of isothiocyanates on tumorigenesis by benzo[a]pyrene in murine tumor models. , 1993, Cancer letters.
[49] S. Belinsky,et al. The A/J mouse lung as a model for developing new chemointervention strategies. , 1993, Cancer research.
[50] P. Thomas,et al. Effects of phenethyl isothiocyanate, a carcinogenesis inhibitor, on xenobiotic-metabolizing enzymes and nitrosamine metabolism in rats. , 1992, Carcinogenesis.
[51] S. Ben‐Sasson,et al. Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation , 1992, The Journal of cell biology.
[52] S. Belinsky,et al. Role of the alveolar type II cell in the development and progression of pulmonary tumors induced by 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in the A/J mouse. , 1992, Cancer research.
[53] R. Maronpot,et al. Proliferative lesions of the mouse lung: progression studies in strain A mice. , 1991, Experimental lung research.
[54] F. Chung,et al. Distribution and metabolism of the natural anticarcinogen phenethyl isothiocyanate in A/J mice. , 1990, Carcinogenesis.
[55] S. Hecht,et al. Advances in Tobacco Carcinogenesis , 1990 .
[56] E. Wynder,et al. Reduction in risk of lung cancer among ex‐smokers with particular reference to histologic type , 1988, Cancer.
[57] J. Fleiss. The design and analysis of clinical experiments , 1987 .
[58] John D. Adams,et al. Chemical studies on tobacco smoke. LXXV: Rapid method for the analysis of tobacco-specific N-nitrosamines by gas-liquid chromatography with a thermal energy analyser , 1983 .
[59] R. Heaney,et al. Glucosinolates and their breakdown products in food and food plants. , 1983, Critical reviews in food science and nutrition.
[60] S. Hecht,et al. Chemical Studies on Tobacco Smoke: LI: Studies on Non-Volatile Nitrosamines in Tobacco , 1977 .
[61] L. Wattenberg. Inhibition of carcinogenic effects of polycyclic hydrocarbons by benzyl isothiocyanate and related compounds. , 1977, Journal of the National Cancer Institute.
[62] J. Peto,et al. Asymptotically Efficient Rank Invariant Test Procedures , 1972 .
[63] E. Kaplan,et al. Nonparametric Estimation from Incomplete Observations , 1958 .
[64] C. Dunnett. A Multiple Comparison Procedure for Comparing Several Treatments with a Control , 1955 .
[65] H. Schmid,et al. Synthese der racemischen und der optisch aktiven Formen des Sulforaphans , 1948 .