An automated, polymer-assisted strategy for the preparation of urea and thiourea derivatives of 15-membered azalides as potential antimalarial chemotherapeutics.

[1]  K. Haldar,et al.  Malaria: mechanisms of erythrocytic infection and pathological correlates of severe disease. , 2007, Annual review of pathology.

[2]  M. Fukuda,et al.  Azithromycin combination therapy with artesunate or quinine for the treatment of uncomplicated Plasmodium falciparum malaria in adults: a randomized, phase 2 clinical trial in Thailand. , 2006, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

[3]  C. Wongsrichanalai,et al.  Effective treatment of uncomplicated Plasmodium falciparum malaria with azithromycin-quinine combinations: a randomized, dose-ranging study. , 2006, The American journal of tropical medicine and hygiene.

[4]  V. Dev,et al.  A double-blind, randomized study of azithromycin compared to chloroquine for the treatment of Plasmodium vivax malaria in India. , 2005, The American journal of tropical medicine and hygiene.

[5]  D. Kyle,et al.  Randomized, controlled, double-blind trial of daily oral azithromycin in adults for the prophylaxis of Plasmodium vivax malaria in Western Thailand. , 2005, The American journal of tropical medicine and hygiene.

[6]  Mario Cindrić,et al.  Synthesis, Characterization and In Vitro Antimicrobial Activity of Novel Sulfonylureas of 15-Membered Azalides , 2005, The Journal of Antibiotics.

[7]  R. Benner,et al.  A multicenter study of azithromycin, alone and in combination with chloroquine, for the treatment of acute uncomplicated Plasmodium falciparum malaria in India. , 2005, The Journal of infectious diseases.

[8]  S. Hay,et al.  The global distribution of clinical episodes of Plasmodium falciparum malaria , 2005, Nature.

[9]  M. Molyneux,et al.  Impairment of humoral immunity to Plasmodium falciparum malaria in pregnancy by HIV infection , 2004, The Lancet.

[10]  M. Ladlow,et al.  A fluorous-tagged, acid-labile protecting group for the synthesis of carboxamides and sulfonamides. , 2004, Journal of combinatorial chemistry.

[11]  Andrew J Tatem,et al.  The global distribution and population at risk of malaria: past, present, and future. , 2004, The Lancet. Infectious diseases.

[12]  Nicholas J White,et al.  Antimalarial drug resistance. , 2004, The Journal of clinical investigation.

[13]  M. Congreve,et al.  A novel phase-switching protecting group for multi-step parallel solution phase synthesis. , 2004, Organic & biomolecular chemistry.

[14]  A. Nzila,et al.  Antimalarial chemotherapy: young guns or back to the future? , 2003, Trends in parasitology.

[15]  F. Dörwald Organic Synthesis on Solid Phase , 2002 .

[16]  Ramanan Laxminarayan,et al.  Malaria: current status of control, diagnosis, treatment, and a proposed agenda for research and development. , 2002, The Lancet. Infectious diseases.

[17]  J. Yoshida,et al.  Tag strategy for separation and recovery. , 2002, Chemical reviews.

[18]  W. Milhous,et al.  Assessment of Azithromycin in Combination with Other Antimalarial Drugs against Plasmodium falciparum In Vitro , 2002, Antimicrobial Agents and Chemotherapy.

[19]  L. Angenot,et al.  New trends in anti-malarial agents. , 2002, Current medicinal chemistry.

[20]  K. O'Brien,et al.  Randomized trial of presumptive sexually transmitted disease therapy during pregnancy in Rakai, Uganda. , 2001, American journal of obstetrics and gynecology.

[21]  W. Wernsdorfer,et al.  Antimalarial activity of azithromycin, artemisinin and dihydroartemisinin in fresh isolates of Plasmodium falciparum in Thailand. , 2001, Acta tropica.

[22]  Ramavatar Sharma,et al.  Recent Developments on the Chemistry and Biological Activity of Artemisinin and Related Antimalarials — An Update , 1999 .

[23]  D. Obrecht,et al.  Solid-Supported Combinatorial and Parallel Synthesis of Small-Molecular-Weight Compound Libraries , 1998 .

[24]  Wei-shan Zhou,et al.  Total Synthesis of the Antimalarial Sesquiterpene Peroxide Qinghaosu and Yingzhaosu A , 1994 .

[25]  D. L. Klayman,et al.  Qinghaosu (artemisinin): an antimalarial drug from China , 1985 .

[26]  A Ganesan,et al.  Recent developments in combinatorial organic synthesis. , 2002, Drug discovery today.

[27]  J. Breman,et al.  The ears of the hippopotamus: manifestations, determinants, and estimates of the malaria burden. , 2001, The American journal of tropical medicine and hygiene.

[28]  H. Basri,et al.  Malaria prophylaxis using azithromycin: a double-blind, placebo-controlled trial in Irian Jaya, Indonesia. , 1999, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

[29]  J. Berman,et al.  Successful double-blinded, randomized, placebo-controlled field trial of azithromycin and doxycycline as prophylaxis for malaria in western Kenya. , 1998, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

[30]  N. White,et al.  Drug resistance in malaria. , 1998, British medical bulletin.

[31]  J. Cumming,et al.  Antimalarial activity of artemisinin (qinghaosu) and related trioxanes: mechanism(s) of action. , 1997, Advances in pharmacology.

[32]  M. Perkins,et al.  Chapter 15. Chemotherapy of Malaria , 1996 .

[33]  Ram P. Sharma,et al.  Some aspects of the chemistry and biological activity of artemisinin and related antimalarials , 1991 .

[34]  X. Luo,et al.  The chemistry, pharmacology, and clinical applications of qinghaosu (Artemisinin) and its derivatives , 1987, Medicinal research reviews.