Urupocidin C: a new marine guanidine alkaloid which selectively kills prostate cancer cells via mitochondria targeting
暂无分享,去创建一个
C. Bokemeyer | M. Graefen | S. Fedorov | L. Shubina | V. Stonik | T. Makarieva | V. Denisenko | S. Dyshlovoy | G. von Amsberg | Moritz Kaune | J. Hauschild | R. Popov | Tobias Busenbender | Ekaterina K. Kudryashova
[1] F. Honecker,et al. Marine Compounds and Cancer: The First Two Decades of XXI Century , 2019, Marine drugs.
[2] H. Schlüter,et al. Successful Targeting of the Warburg Effect in Prostate Cancer by Glucose-Conjugated 1,4-Naphthoquinones , 2019, Cancers.
[3] J. Neuzil,et al. Targeting mitochondria as an anticancer strategy , 2019, Cancer communications.
[4] M. Farag,et al. Marine Natural Products: A Source of Novel Anticancer Drugs , 2019, Marine drugs.
[5] L. Shubina,et al. Monanchoxymycalin C with anticancer properties, new analogue of crambescidin 800 from the marine sponge Monanchora pulchra , 2019, Natural product research.
[6] V. Ivanenko,et al. Express Method for Isolation of Ready-to-Use 3D Chitin Scaffolds from Aplysina archeri (Aplysineidae: Verongiida) Demosponge , 2019, Marine drugs.
[7] I. Faraoni,et al. Role of BRCA Mutations in Cancer Treatment with Poly(ADP-ribose) Polymerase (PARP) Inhibitors , 2018, Cancers.
[8] N. Nonomura,et al. Role of Androgen Receptor in Prostate Cancer: A Review , 2018, The world journal of men's health.
[9] Joo Young Lee,et al. Mitochondrial-Targeting Anticancer Agent Conjugates and Nanocarrier Systems for Cancer Treatment , 2018, Front. Pharmacol..
[10] S. Bornstein,et al. Anti-Tumorigenic and Anti-Metastatic Activity of the Sponge-Derived Marine Drugs Aeroplysinin-1 and Isofistularin-3 against Pheochromocytoma In Vitro , 2018, Marine drugs.
[11] S. Kaplan,et al. The molecular biology of prostate cancer: current understanding and clinical implications , 2017, Prostate Cancer and Prostatic Diseases.
[12] C. Bokemeyer,et al. Synthesis and anticancer activity of the derivatives of marine compound rhizochalin in castration resistant prostate cancer , 2018, Oncotarget.
[13] M. Hermann,et al. Olaparib is effective in combination with, and as maintenance therapy after, first‐line endocrine therapy in prostate cancer cells , 2018, Molecular oncology.
[14] H. Ehrlich,et al. Marine Spongin: Naturally Prefabricated 3D Scaffold-Based Biomaterial , 2018, Marine drugs.
[15] M. Rubin,et al. Clinical Outcome of Prostate Cancer Patients with Germline DNA Repair Mutations: Retrospective Analysis from an International Study , 2018, European urology.
[16] anonymous. In Review , 2018 .
[17] A. Bishayee,et al. Batzella, Crambe and Monanchora: Highly Prolific Marine Sponge Genera Yielding Compounds with Potential Applications for Cancer and Other Therapeutic Areas , 2018, Nutrients.
[18] Stelamar Romminger,et al. The chemistry and biology of guanidine natural products. , 2017, Natural product reports.
[19] J. Joseph,et al. A review of the basics of mitochondrial bioenergetics, metabolism, and related signaling pathways in cancer cells: Therapeutic targeting of tumor mitochondria with lipophilic cationic compounds , 2017, Redox biology.
[20] J. Joseph,et al. Mitochondria-Targeted Triphenylphosphonium-Based Compounds: Syntheses, Mechanisms of Action, and Therapeutic and Diagnostic Applications. , 2017, Chemical reviews.
[21] Y. Moazami,et al. Structure, synthesis and biological properties of the pentacyclic guanidinium alkaloids. , 2017, Bioorganic & medicinal chemistry.
[22] C. Bokemeyer,et al. Frondoside A induces AIF-associated caspase-independent apoptosis in Burkitt lymphoma cells , 2017, Leukemia & lymphoma.
[23] Yuliya V. Korolkova,et al. Marine Cyclic Guanidine Alkaloids Monanchomycalin B and Urupocidin A Act as Inhibitors of TRPV1, TRPV2 and TRPV3, but not TRPA1 Receptors , 2017, Marine drugs.
[24] Alan Ashworth,et al. PARP inhibitors: Synthetic lethality in the clinic , 2017, Science.
[25] C. Bokemeyer,et al. The marine triterpene glycoside frondoside A induces p53-independent apoptosis and inhibits autophagy in urothelial carcinoma cells , 2017, BMC Cancer.
[26] Ying Feng,et al. Nomogram prediction of individual prognosis of patients with hepatocellular carcinoma , 2017, BMC Cancer.
[27] K. Hall,et al. Cytotoxic Guanidine Alkaloids from a French Polynesian Monanchora n. sp. Sponge. , 2016, Journal of natural products.
[28] C. Bokemeyer,et al. Guanidine Alkaloids from the Marine Sponge Monanchora pulchra Show Cytotoxic Properties and Prevent EGF-Induced Neoplastic Transformation in Vitro , 2016, Marine drugs.
[29] T. Zhu,et al. Austalides S-U, New Meroterpenoids from the Sponge-Derived Fungus Aspergillus aureolatus HDN14-107 , 2016, Marine drugs.
[30] H. Malve. Exploring the ocean for new drug developments: Marine pharmacology , 2016, Journal of pharmacy & bioallied sciences.
[31] Hyung-Ryong Kim,et al. Endoplasmic Reticulum Stress and Associated ROS , 2016, International journal of molecular sciences.
[32] Yongkyun Kim,et al. Single-molecule visualization of ROS-induced DNA damage in large DNA molecules. , 2016, The Analyst.
[33] Wei Yuan,et al. DNA-Repair Defects and Olaparib in Metastatic Prostate Cancer. , 2015, The New England journal of medicine.
[34] M. Fini,et al. Deep sea as a source of novel-anticancer drugs , 2015 .
[35] W. Isaacs,et al. AR-V7 and resistance to enzalutamide and abiraterone in prostate cancer. , 2014, The New England journal of medicine.
[36] P. Nelson. Targeting the androgen receptor in prostate cancer--a resilient foe. , 2014, The New England journal of medicine.
[37] V. Stonik,et al. Urupocidin A: a new, inducing iNOS expression bicyclic guanidine alkaloid from the marine sponge Monanchora pulchra. , 2014, Organic letters.
[38] C. Bokemeyer,et al. Aaptamines from the Marine Sponge Aaptos sp. Display Anticancer Activities in Human Cancer Cell Lines and Modulate AP-1-, NF-κB-, and p53-Dependent Transcriptional Activity in Mouse JB6 Cl41 Cells , 2014, BioMed research international.
[39] S. Sollott,et al. Mitochondrial reactive oxygen species (ROS) and ROS-induced ROS release. , 2014, Physiological reviews.
[40] N. Weigel,et al. Androgen receptors in hormone-dependent and castration-resistant prostate cancer. , 2013, Pharmacology & therapeutics.
[41] Bradley S Moore,et al. Lessons from the past and charting the future of marine natural products drug discovery and chemical biology. , 2012, Chemistry & biology.
[42] Vaibhav Saxena,et al. Approaches for targeting mitochondria in cancer therapy. , 2011, Biochimica et biophysica acta.
[43] R. Hill,et al. Marine Natural Products , 2011, Topics in Heterocyclic Chemistry.
[44] V. Stepanov,et al. Genomes, Populations and Diseases: Ethnic Genomics and Personalized Medicine , 2010, Acta naturae.
[45] T. Chou. Drug combination studies and their synergy quantification using the Chou-Talalay method. , 2010, Cancer research.
[46] V. Stonik,et al. Marine Natural Products: A Way to New Drugs , 2009, Acta naturae.
[47] Peng Huang,et al. Targeting cancer cells by ROS-mediated mechanisms: a radical therapeutic approach? , 2009, Nature Reviews Drug Discovery.
[48] Stonik Va. Marine natural products: a way to new drugs , 2009 .
[49] Robin A. J. Smith,et al. Targeting antioxidants to mitochondria by conjugation to lipophilic cations. , 2007, Annual review of pharmacology and toxicology.
[50] Ting-Chao Chou,et al. Theoretical Basis, Experimental Design, and Computerized Simulation of Synergism and Antagonism in Drug Combination Studies , 2006, Pharmacological Reviews.
[51] C. Bewley,et al. Crambescidin 826 and dehydrocrambine A: new polycyclic guanidine alkaloids from the marine sponge Monanchora sp. that inhibit HIV-1 fusion. , 2003, Journal of natural products.
[52] D. Green,et al. Caspase-mediated loss of mitochondrial function and generation of reactive oxygen species during apoptosis , 2003, The Journal of cell biology.
[53] Dean P. Jones,et al. Prevention of Apoptosis by Bcl-2: Release of Cytochrome c from Mitochondria Blocked , 1997, Science.
[54] G. Palade,et al. The fine structure of mitochondria , 1952, The Anatomical record.
[55] Robert A. Keyzers,et al. Marine natural products. , 2019, Natural product reports.
[56] M. Takaki,et al. The chemistry and biology of guanidine natural products. , 2017, Natural product reports.
[57] B. Mignotte,et al. The mitochondrial pathways of apoptosis. , 2012, Advances in experimental medicine and biology.
[58] T. Molinski,et al. Drug development from marine natural products , 2009, Nature Reviews Drug Discovery.
[59] Lorenzo Galluzzi,et al. Mitochondrial membrane permeabilization in cell death. , 2007, Physiological reviews.
[60] D. Faulkner,et al. Marine pharmacology , 2004, Antonie van Leeuwenhoek.
[61] D. Faulkner. Marine natural products. , 2000, Natural product reports.
[62] W. E. Thompson,et al. Nuclear magnetic resonance spectra of amines. I. Identification of N-methyl tertiary amines. , 1966, Journal of pharmaceutical sciences.