Abnormal Regenerative Responses and Impaired Axonal Outgrowth after Nerve Crush in TDP-43 Transgenic Mouse Models of Amyotrophic Lateral Sclerosis
暂无分享,去创建一个
J. Julien | V. Swarup | J. Kriz | J. Audet | D. Phaneuf
[1] S. Petri,et al. Deregulation of TDP-43 in amyotrophic lateral sclerosis triggers nuclear factor κB–mediated pathogenic pathways , 2011, The Journal of experimental medicine.
[2] Fred A Wright,et al. Microarray analysis of peripheral blood lymphocytes from ALS patients and the SAFE detection of the KEGG ALS pathway , 2011, BMC Medical Genomics.
[3] V. Torri,et al. Amyotrophic Lateral Sclerosis Multiprotein Biomarkers in Peripheral Blood Mononuclear Cells , 2011, PloS one.
[4] J. Julien,et al. Pathological hallmarks of amyotrophic lateral sclerosis/frontotemporal lobar degeneration in transgenic mice produced with TDP-43 genomic fragments. , 2011, Brain : a journal of neurology.
[5] J. Kriz,et al. Treatment with minocycline after disease onset alters astrocyte reactivity and increases microgliosis in SOD1 mutant mice , 2011, Experimental Neurology.
[6] D. Burns,et al. Progressive motor weakness in transgenic mice expressing human TDP-43 , 2010, Neurobiology of Disease.
[7] L. Petrucelli,et al. Wild-Type Human TDP-43 Expression Causes TDP-43 Phosphorylation, Mitochondrial Aggregation, Motor Deficits, and Early Mortality in Transgenic Mice , 2010, The Journal of Neuroscience.
[8] D. Price,et al. Deletion of TDP-43 down-regulates Tbc1d1, a gene linked to obesity, and alters body fat metabolism , 2010, Proceedings of the National Academy of Sciences.
[9] J. C. Baayen,et al. Tissue plasminogen activator and urokinase plasminogen activator in human epileptogenic pathologies , 2010, Neuroscience.
[10] S. Pereson,et al. TDP-43 transgenic mice develop spastic paralysis and neuronal inclusions characteristic of ALS and frontotemporal lobar degeneration , 2010, Proceedings of the National Academy of Sciences.
[11] C. Sephton,et al. TDP-43 Is a Developmentally Regulated Protein Essential for Early Embryonic Development* , 2009, The Journal of Biological Chemistry.
[12] N. Cairns,et al. TDP-43 mutant transgenic mice develop features of ALS and frontotemporal lobar degeneration , 2009, Proceedings of the National Academy of Sciences.
[13] M. Strong,et al. Cytosolic TDP-43 expression following axotomy is associated with caspase 3 activation in NFL−/− mice: Support for a role for TDP-43 in the physiological response to neuronal injury , 2009, Brain Research.
[14] A Florence Keller,et al. Live imaging of amyotrophic lateral sclerosis pathogenesis: Disease onset is characterized by marked induction of GFAP in Schwann cells , 2009, Glia.
[15] G. Glazner,et al. Nuclear Factor-&kgr;B Activation in Axons and Schwann Cells in Experimental Sciatic Nerve Injury and Its Role in Modulating Axon Regeneration: Studies With Etanercept , 2009, Journal of neuropathology and experimental neurology.
[16] M. Strong,et al. Divergent patterns of cytosolic TDP-43 and neuronal progranulin expression following axotomy: Implications for TDP-43 in the physiological response to neuronal injury , 2009, Brain Research.
[17] K. Abe,et al. Ubiquitin-Mediated Stress Response in the Spinal Cord After Transient Ischemia , 2008, Stroke.
[18] B. McConkey,et al. TARDBP mutations in individuals with sporadic and familial amyotrophic lateral sclerosis , 2008, Nature Genetics.
[19] Murray Grossman,et al. TARDBP mutations in amyotrophic lateral sclerosis with TDP-43 neuropathology: a genetic and histopathological analysis , 2008, The Lancet Neurology.
[20] J. Morris,et al. TDP‐43 A315T mutation in familial motor neuron disease , 2008, Annals of neurology.
[21] Xun Hu,et al. TDP-43 Mutations in Familial and Sporadic Amyotrophic Lateral Sclerosis , 2008, Science.
[22] M. Strong,et al. TDP43 is a human low molecular weight neurofilament (hNFL) mRNA-binding protein , 2007, Molecular and Cellular Neuroscience.
[23] R Carmona,et al. A simple technique of image analysis for specific nuclear immunolocalization of proteins , 2007, Journal of microscopy.
[24] H. Akiyama,et al. TDP-43 is a component of ubiquitin-positive tau-negative inclusions in frontotemporal lobar degeneration and amyotrophic lateral sclerosis. , 2006, Biochemical and biophysical research communications.
[25] Bruce L. Miller,et al. Ubiquitinated TDP-43 in Frontotemporal Lobar Degeneration and Amyotrophic Lateral Sclerosis , 2006, Science.
[26] E. Aronica,et al. The IL-1β system in epilepsy-associated malformations of cortical development , 2006, Neurobiology of Disease.
[27] J. Julien,et al. Induction of peripherin expression in subsets of brain neurons after lesion injury or cerebral ischemia , 2002, Brain Research.
[28] J. Julien,et al. Delayed Maturation of Regenerating Myelinated Axons in Mice Lacking Neurofilaments , 1997, Experimental Neurology.
[29] J. Kiernan,et al. Increased production of ubiquitin mRNA in motor neurons after axotomy , 1994, Neuropathology and applied neurobiology.
[30] T. Yaksh,et al. Transient Spinal Ischemia in the Rat: Characterization of Behavioral and Histopathological Consequences as a Function of the Duration of Aortic Occlusion , 1994, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.
[31] D. Schiffer,et al. Peripherin immunoreactive structures in amyotrophic lateral sclerosis. , 1993, Laboratory investigation; a journal of technical methods and pathology.
[32] A. Hays,et al. Peripherin and Neurofilament Protein Coexist in Spinal Spheroids of Motor Neuron Disease , 1992, Journal of neuropathology and experimental neurology.
[33] D. Price,et al. Regulation of peripherin and neurofilament expression in regenerating rat motor neurons , 1990, Brain Research.
[34] S. Carpenter. Proximal axonal enlargement in motor neuron disease , 1968, Neurology.
[35] D. Mann,et al. Increased TDP-43 protein in cerebrospinal fluid of patients with amyotrophic lateral sclerosis , 2008, Acta Neuropathologica.