Genetic and Inflammatory Biomarkers Classify Small Intestine Inflammation in Asymptomatic First-degree Relatives of Patients With Crohn's Disease.

[1]  D. Kao,et al.  Increased Intestinal Permeability in Relatives of Patients With Crohn’s Disease Is Not Associated With Small Bowel Ulcerations , 2017, Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association.

[2]  David C. Wilson,et al.  Genome-wide association study implicates immune activation of multiple integrin genes in inflammatory bowel disease , 2016, Nature Genetics.

[3]  W. Reinisch,et al.  Fecal calprotectin: its scope and utility in the management of inflammatory bowel disease , 2016, Journal of Gastroenterology.

[4]  A. Paterson,et al.  IBD Genetic Risk Profile in Healthy First-Degree Relatives of Crohn's Disease Patients. , 2016, Journal of Crohn's & colitis.

[5]  Andreas Ziegler,et al.  ranger: A Fast Implementation of Random Forests for High Dimensional Data in C++ and R , 2015, 1508.04409.

[6]  Judy H. Cho,et al.  Association analyses identify 38 susceptibility loci for inflammatory bowel disease and highlight shared genetic risk across populations , 2015, Nature Genetics.

[7]  V. Andersen,et al.  Heritability in Inflammatory Bowel Disease: From the First Twin Study to Genome-Wide Association Studies , 2015, Inflammatory bowel diseases.

[8]  Ashwin N. Ananthakrishnan,et al.  Epidemiology and risk factors for IBD , 2015, Nature Reviews Gastroenterology &Hepatology.

[9]  T. Dassopoulos,et al.  Tissue Studies in Screened First-degree Relatives Reveal a Distinct Crohn's Disease Phenotype , 2014, Inflammatory bowel diseases.

[10]  T. Dassopoulos,et al.  Su1317 Tissue Studies in Screened First Degree Relatives Reveal a Distinct Crohn's Disease Phenotype , 2014 .

[11]  S. Vermeire,et al.  Fecal calprotectin is a surrogate marker for endoscopic lesions in inflammatory bowel disease , 2012, Inflammatory bowel diseases.

[12]  W. Sandborn,et al.  Crohn's disease , 2012, The Lancet.

[13]  C. Lewis,et al.  REGENT: a risk assessment and classification algorithm for genetic and environmental factors , 2012, European Journal of Human Genetics.

[14]  K. Madsen,et al.  220 Asymptomatic First Degree Relatives of Crohn's Patients Display Endoscopic Small Intestinal Lesions Independent of Their Gut Permeability Status , 2012 .

[15]  Anastasios Koulaouzidis,et al.  Lewis Score Correlates More Closely with Fecal Calprotectin Than Capsule Endoscopy Crohn’s Disease Activity Index , 2011, Digestive Diseases and Sciences.

[16]  K. Whelan,et al.  Family studies in Crohn's disease: new horizons in understanding disease pathogenesis, risk and prevention , 2011, Gut.

[17]  M. Brown,et al.  Promise and pitfalls of the Immunochip , 2011, Arthritis research & therapy.

[18]  Tariq Ahmad,et al.  Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci , 2010, Nature Genetics.

[19]  C. Lewis,et al.  Risk categorization for complex disorders according to genotype relative risk and precision in parameter estimates , 2010, Genetic epidemiology.

[20]  Trevor Hastie,et al.  Regularization Paths for Generalized Linear Models via Coordinate Descent. , 2010, Journal of statistical software.

[21]  Trevor J. Hastie,et al.  Genome-wide association analysis by lasso penalized logistic regression , 2009, Bioinform..

[22]  Y. Niv,et al.  Assessment and Validation of the New Capsule Endoscopy Crohn’s Disease Activity Index (CECDAI) , 2008, Digestive Diseases and Sciences.

[23]  S. Fisher,et al.  Diverse effects of the CARD15 and IBD5 loci on clinical phenotype in 630 patients with Crohn's disease , 2008, European journal of gastroenterology & hepatology.

[24]  E. Seidman,et al.  Development of a capsule endoscopy scoring index for small bowel mucosal inflammatory change , 2007, Alimentary pharmacology & therapeutics.

[25]  Manuel A. R. Ferreira,et al.  PLINK: a tool set for whole-genome association and population-based linkage analyses. , 2007, American journal of human genetics.

[26]  S. Fisher,et al.  A nonsynonymous SNP in ATG16L1 predisposes to ileal Crohn's disease and is independent of CARD15 and IBD5. , 2007, Gastroenterology.

[27]  S. Brant,et al.  A Population-Based Case-Control Study of CARD15 and Other Risk Factors in Crohn's Disease and Ulcerative Colitis , 2007, The American Journal of Gastroenterology.

[28]  S. Galandiuk,et al.  Smoking and inflammatory bowel disease: a meta-analysis. , 2006, Mayo Clinic proceedings.

[29]  A. Trentham-Dietz,et al.  Familial relative risk estimates for use in epidemiologic analyses. , 2006, American journal of epidemiology.

[30]  U. Turunen,et al.  Family and twin studies in inflammatory bowel disease. , 2006, World journal of gastroenterology.

[31]  N. Graham,et al.  Areas beneath the relative operating characteristics (ROC) and relative operating levels (ROL) curves: Statistical significance and interpretation , 2002 .

[32]  D. Hosmer,et al.  Applied Logistic Regression , 1991 .

[33]  R. Mendes R: The R Project for Statistical Computing , 2016 .

[34]  Subrata Ghosh,et al.  Increasing incidence and prevalence of the inflammatory bowel diseases with time, based on systematic review. , 2012, Gastroenterology.

[35]  David C. Wilson,et al.  Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease , 2012, Nature.

[36]  P. Borgiani,et al.  A family study of asymptomatic small bowel Crohn's disease. , 2014, Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver.