Generation of a locomotory rhythm by a neural network with recurrent cyclic inhibition

An oscillatory intersegmental neuronal network drives the swimming rhythm of the leech. This network consists of interneurons joined via inhibitory connections to form a series of segmentally iterated, concatenated rings. Recurrent cyclic inhibition in these rings produces a multiphasic activity rhythm. By theoretical analysis of such concatenated interneuronal rings and construction of their electronic analogs it is shown that the interneural network identified in the central nervous system of the leech has properties appropriate for generating the observed motor output.

[1]  T. Bullock.  THE ORIGINS OF PATTERNED NERVOUS DISCHARGE , 1961 .

[2]  Richard F. Reiss,et al.  A theory and simulation of rhythmic behavior due to reciprocal inhibition in small nerve nets , 1899, AIEE-IRE '62 (Spring).

[3]  G SZEKELY,et al.  LOGICAL NETWORK FOR CONTROLLING LIMB MOVEMENTS IN URODELA. , 1965, Acta physiologica Academiae Scientiarum Hungaricae.

[4]  D. M. Wilson.  Central nervous mechanisms for the generation of rhythmic behaviour in arthropods. , 1966, Symposia of the Society for Experimental Biology.

[5]  J. Edwards.  Nervous and Hormonal Mechanisms of Integration , 1967 .

[6]  B. O. Alving.  Spontaneous Activity in Isolated Somata of Aplysia Pacemaker Neurons , 1968, The Journal of general physiology.

[7]  E. Lewis.  Using electronic circuits to model simple neuroelectric interactions , 1968 .

[8]  Donald M. Wilson,et al.  Models for the generation of the motor output pattern in flying locusts , 1968 .

[9]  V. L. Dunin-Barkovskii.  [Variations in the activity level in simple closed neuron chains]. , 1970, Biofizika.

[10]  Dunin-Barkovskiĭ Vl.  Variations in the activity level in simple closed neuron chains , 1970 .

[11]  Pozin Nv,et al.  Analysis of the work of autooscillating neuron combinations , 1970 .

[12]  D. Perkel,et al.  Motor Pattern Production in Reciprocally Inhibitory Neurons Exhibiting Postinhibitory Rebound , 1974, Science.

[13]  W. Kristan,et al.  Rhythmic swimming activity in neurones of the isolated nerve cord of the leech. , 1976, The Journal of experimental biology.

[14]  W. O. Friesen,et al.  An oscillatory neuronal circuit generating a locomotory rhythm. , 1976, Proceedings of the National Academy of Sciences of the United States of America.

[15]  Neuronal control of swimming in the medicinal leech , 1974, Journal of comparative physiology.

[16]  G. Stent,et al.  Neuronal control of swimming in the medicinal leech , 1974, Journal of comparative physiology.

[17]  G. Székely,et al.  Simulation of rhythmic nervous activities , 1968, Kybernetik.

[18]  A. Ádám.  Simulation of rhythmic nervous activities , 1968, Kybernetik.

[19]  G. Stent,et al.  Neuronal control of swimming in the medicinal leech , 1974, Journal of comparative physiology.

[20]  A. Adxm.  Simulation of Rhythmic Nervous Activities II . Mathematical Models for the Function of Networks with Cyclic Inhibition , 2022 .