An inducible ER–Golgi tether facilitates ceramide transport to alleviate lipotoxicity
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[1] M. Schuldiner,et al. Making Sense of the Yeast Sphingolipid Pathway. , 2016, Journal of molecular biology.
[2] J. Napier,et al. Plant sphingolipids: Their importance in cellular organization and adaption , 2016, Biochimica et biophysica acta.
[3] R. Schneiter,et al. Following the flux of long-chain bases through the sphingolipid pathway in vivo using mass spectrometry[S] , 2016, Journal of Lipid Research.
[4] Daniel R. Gulbranson,et al. Extended synaptotagmins are Ca2+-dependent lipid transfer proteins at membrane contact sites , 2016, Proceedings of the National Academy of Sciences.
[5] P. De Camilli,et al. Control of plasma membrane lipid homeostasis by the extended synaptotagmins , 2016, Nature Cell Biology.
[6] N. Ridgway,et al. Oxysterol-binding Protein Activation at Endoplasmic Reticulum-Golgi Contact Sites Reorganizes Phosphatidylinositol 4-Phosphate Pools* , 2015, The Journal of Biological Chemistry.
[7] R. Teasdale,et al. Modular Detection of GFP-Labeled Proteins for Rapid Screening by Electron Microscopy in Cells and Organisms. , 2015, Developmental cell.
[8] W. Prinz,et al. A conserved family of proteins facilitates nascent lipid droplet budding from the ER , 2022 .
[9] M. D. De Matteis,et al. Endoplasmic reticulum-Golgi complex membrane contact sites. , 2015, Current opinion in cell biology.
[10] Z. Zhou,et al. Conserved SMP domains of the ERMES complex bind phospholipids and mediate tether assembly , 2015, Proceedings of the National Academy of Sciences.
[11] Mark H. Ellisman,et al. Supplementary Text: Mechanistic Investigation of Apex2 , 2014 .
[12] P. De Camilli,et al. Structure of a lipid-bound Extended-Synaptotagmin indicates a role in lipid transfer , 2014, Nature.
[13] M. Tani,et al. New insight into the structure, reaction mechanism, and biological functions of neutral ceramidase. , 2014, Biochimica et biophysica acta.
[14] A. Nakano,et al. Contact of cis-Golgi with ER exit sites executes cargo capture and delivery from the ER , 2014, Nature Communications.
[15] M. Hermansson,et al. Sphingomyelin synthase-related protein SMSr is a suppressor of ceramide-induced mitochondrial apoptosis , 2014, Journal of Cell Science.
[16] H. Riezman,et al. Osh proteins regulate COPII-mediated vesicular transport of ceramide from the endoplasmic reticulum in budding yeast , 2014, Journal of Cell Science.
[17] G. Drin,et al. A Four-Step Cycle Driven by PI(4)P Hydrolysis Directs Sterol/PI(4)P Exchange by the ER-Golgi Tether OSBP , 2013, Cell.
[18] T. Eisenberg,et al. Lipids and cell death in yeast , 2013, FEMS yeast research.
[19] W. Oppliger,et al. TORC1-regulated protein kinase Npr1 phosphorylates Orm to stimulate complex sphingolipid synthesis , 2013, Molecular biology of the cell.
[20] Y. Hannun,et al. Modulation of Mitochondrial Outer Membrane Permeabilization and Apoptosis by Ceramide Metabolism , 2012, PloS one.
[21] Christer S. Ejsing,et al. A novel pathway of ceramide metabolism in Saccharomyces cerevisiae. , 2012, The Biochemical journal.
[22] Mark H. Ellisman,et al. Engineered ascorbate peroxidase as a genetically-encoded reporter for electron microscopy , 2012, Nature Biotechnology.
[23] R. Schneiter,et al. Regulation of sphingolipid synthesis through Orm1 and Orm2 in yeast , 2012, Journal of Cell Science.
[24] L. Obeid,et al. Ceramide and apoptosis: exploring the enigmatic connections between sphingolipid metabolism and programmed cell death. , 2012, Anti-cancer agents in medicinal chemistry.
[25] W. Prinz,et al. A conserved membrane-binding domain targets proteins to organelle contact sites , 2012, Journal of Cell Science.
[26] S. Summers,et al. Ceramides as modulators of cellular and whole-body metabolism. , 2011, The Journal of clinical investigation.
[27] D. Pincus,et al. Homeostatic adaptation to endoplasmic reticulum stress depends on Ire1 kinase activity , 2011, The Journal of cell biology.
[28] P. Bork,et al. A systematic screen for protein–lipid interactions in Saccharomyces cerevisiae , 2010, Molecular systems biology.
[29] R. Schneiter,et al. Orm1 and Orm2 are conserved endoplasmic reticulum membrane proteins regulating lipid homeostasis and protein quality control , 2010, Proceedings of the National Academy of Sciences.
[30] H. Yun,et al. Effect of expression of genes in the sphingolipid synthesis pathway on the biosynthesis of ceramide in Saccharomyces cerevisiae. , 2010, Journal of microbiology and biotechnology.
[31] Christer S. Ejsing,et al. Orm family proteins mediate sphingolipid homeostasis , 2010, Nature.
[32] J. Brouwers,et al. Sphingomyelin synthase SMS2 displays dual activity as ceramide phosphoethanolamine synthase[S] , 2009, Journal of Lipid Research.
[33] Peter Walter,et al. Supporting Online Material for An ER-Mitochondria Tethering Complex Revealed by a Synthetic Biology Screen , 2009 .
[34] J. Brouwers,et al. Sphingomyelin synthase-related protein SMSr controls ceramide homeostasis in the ER , 2009, The Journal of cell biology.
[35] J. Knudsen,et al. Aureobasidin A arrests growth of yeast cells through both ceramide intoxication and deprivation of essential inositolphosphorylceramides , 2009, Molecular microbiology.
[36] S. Lev,et al. Coordinated lipid transfer between the endoplasmic reticulum and the Golgi complex requires the VAP proteins and is essential for Golgi-mediated transport. , 2008, Molecular biology of the cell.
[37] R. Ledeen,et al. Thematic Review Series: Sphingolipids. Nuclear sphingolipids: metabolism and signaling** This study was supported by National Institutes of Health grant 2RO1 NS033912. Published, JLR Papers in Press, March 9, 2008. , 2008, Journal of Lipid Research.
[38] H. Riezman,et al. Yeast ARV1 is required for efficient delivery of an early GPI intermediate to the first mannosyltransferase during GPI assembly and controls lipid flow from the endoplasmic reticulum. , 2008, Molecular biology of the cell.
[39] K. Hanada,et al. Interorganelle Trafficking of Ceramide Is Regulated by Phosphorylation-dependent Cooperativity between the PH and START Domains of CERT* , 2007, Journal of Biological Chemistry.
[40] A. Greenberg,et al. Key Role for Ceramides in Mediating Insulin Resistance in Human Muscle Cells* , 2007, Journal of Biological Chemistry.
[41] M. Birnbaum,et al. Inhibition of ceramide synthesis ameliorates glucocorticoid-, saturated-fat-, and obesity-induced insulin resistance. , 2007, Cell metabolism.
[42] D. Goldfarb,et al. Structure and function of nucleus-vacuole junctions: outer-nuclear-membrane targeting of Nvj1p and a role in tryptophan uptake , 2006, Journal of Cell Science.
[43] Diana Murray,et al. Genome-wide analysis of membrane targeting by S. cerevisiae pleckstrin homology domains. , 2004, Molecular cell.
[44] Satoshi Yasuda,et al. Molecular machinery for non-vesicular trafficking of ceramide , 2003, Nature.
[45] E. O’Shea,et al. Global analysis of protein localization in budding yeast , 2003, Nature.
[46] Alfred H. Merrill,et al. De Novo Sphingolipid Biosynthesis: A Necessary, but Dangerous, Pathway* , 2002, The Journal of Biological Chemistry.
[47] G. Marfany,et al. ORMDL proteins are a conserved new family of endoplasmic reticulum membrane proteins , 2002, Genome Biology.
[48] H. Riezman,et al. Vesicular and nonvesicular transport of ceramide from ER to the Golgi apparatus in yeast , 2001, The Journal of cell biology.
[49] D. Oesterhelt,et al. Lag1p and Lac1p are essential for the Acyl-CoA-dependent ceramide synthase reaction in Saccharomyces cerevisae. , 2001, Molecular biology of the cell.
[50] A. Bielawska,et al. Cloning and Characterization of a Saccharomyces cerevisiae Alkaline Ceramidase with Specificity for Dihydroceramide* , 2000, The Journal of Biological Chemistry.
[51] N. Bulleid,et al. Endoplasmic Reticulum Oxidoreductin 1-Lβ (ERO1-Lβ), a Human Gene Induced in the Course of the Unfolded Protein Response* 210 , 2000, The Journal of Biological Chemistry.
[52] S. Munro,et al. Inositol phosphorylceramide synthase is located in the Golgi apparatus of Saccharomyces cerevisiae. , 2000, Molecular biology of the cell.
[53] D. Goldfarb,et al. Nucleus-vacuole junctions in Saccharomyces cerevisiae are formed through the direct interaction of Vac8p with Nvj1p. , 2000, Molecular biology of the cell.
[54] A. Bielawska,et al. Cloning of an Alkaline Ceramidase from Saccharomyces cerevisiae , 2000, The Journal of Biological Chemistry.
[55] R. Schneiter. Brave little yeast, please guide us to Thebes: sphingolipid function in S. cerevisiae , 1999, BioEssays : news and reviews in molecular, cellular and developmental biology.
[56] R. Lester,et al. Metabolism and selected functions of sphingolipids in the yeast Saccharomyces cerevisiae. , 1999, Biochimica et biophysica acta.
[57] Z. Xie,et al. Phospholipase D activity is required for suppression of yeast phosphatidylinositol transfer protein defects. , 1998, Proceedings of the National Academy of Sciences of the United States of America.
[58] S. Emr,et al. Compartmental organization of Golgi-specific protein modification and vacuolar protein sorting events defined in a yeast sec18 (NSF) mutant. , 1991 .
[59] S. Emr,et al. Compartmental organization of Golgi-specific protein modification and vacuolar protein sorting events defined in a yeast sec18 (NSF) mutant , 1991, The Journal of cell biology.
[60] A. Conzelmann,et al. Biosynthesis of mannosylinositolphosphoceramide in Saccharomyces cerevisiae is dependent on genes controlling the flow of secretory vesicles from the endoplasmic reticulum to the Golgi , 1991, The Journal of cell biology.
[61] N. Bulleid,et al. Endoplasmic reticulum oxidoreductin 1-lbeta (ERO1-Lbeta), a human gene induced in the course of the unfolded protein response. , 2000, The Journal of biological chemistry.
[62] R. Müller,et al. Regulatable promoters of Saccharomyces cerevisiae: comparison of transcriptional activity and their use for heterologous expression. , 1994, Nucleic acids research.