Identification, analysis, and interpretation of a human serum metabolomics causal network in an observational study

[1]  Eric Boerwinkle,et al.  Conceptual Aspects of Causal Networks in an Applied Context , 2016 .

[2]  Fabian J Theis,et al.  Statistical methods for the analysis of high-throughput metabolomics data , 2013, Computational and structural biotechnology journal.

[3]  R. L. Brunner,et al.  Valine, isoleucine, and leucine. A new treatment for phenylketonuria. , 1990, American journal of diseases of children.

[4]  E. Boerwinkle,et al.  Causal Inference in the Age of Decision Medicine , 2014, Journal of data mining in genomics & proteomics.

[5]  A. Barabasi,et al.  Interactome Networks and Human Disease , 2011, Cell.

[6]  Peter Goos,et al.  Sequential imputation for missing values , 2007, Comput. Biol. Chem..

[7]  André R Nelson,et al.  A protein-leucine supplement increases branched-chain amino acid and nitrogen turnover but not performance. , 2012, Medicine and science in sports and exercise.

[8]  Fabian J. Theis,et al.  Gaussian graphical modeling reconstructs pathway reactions from high-throughput metabolomics data , 2011, BMC Systems Biology.

[9]  Halina Kwasnicka,et al.  Fuzzy Classification Method in Credit Risk , 2012, ICCCI.

[10]  D. Raftery,et al.  Metabolomics-based methods for early disease diagnostics , 2008, Expert review of molecular diagnostics.

[11]  T. Meyer,et al.  The production of p-cresol sulfate and indoxyl sulfate in vegetarians versus omnivores. , 2012, Clinical journal of the American Society of Nephrology : CJASN.

[12]  Markus Perola,et al.  Metabonomic, transcriptomic, and genomic variation of a population cohort , 2010, Molecular systems biology.

[13]  Kwanjeera Wanichthanarak,et al.  MetaMapR: pathway independent metabolomic network analysis incorporating unknowns , 2015, Bioinform..

[14]  J. Pearl.  Causality: Models, Reasoning and Inference , 2000 .

[15]  S. Fujita,et al.  Amino acids and muscle loss with aging. , 2006, The Journal of nutrition.

[16]  E. Boerwinkle,et al.  Identification of Rare Variants in Metabolites of the Carnitine Pathway by Whole Genome Sequencing Analysis , 2016, Genetic epidemiology.

[17]  Eric Boerwinkle,et al.  Causal inference at the population level , 2014 .

[18]  A. Folsom,et al.  The Atherosclerosis Risk in Communities (ARIC) Study: design and objectives. The ARIC investigators. , 1989, American journal of epidemiology.

[19]  YazdaniAzam,et al.  A Causal Network Analysis of the Fatty Acid Metabolome in African-Americans Reveals a Critical Role for Palmitoleate and Margarate. , 2016 .

[20]  M. Gerstein,et al.  Getting connected: analysis and principles of biological networks. , 2007, Genes & development.

[21]  S. Mecking,et al.  Long-Chain Aliphatic Polymers To Bridge the Gap between Semicrystalline Polyolefins and Traditional Polycondensates. , 2016, Chemical reviews.

[22]  Halina Kwasnicka,et al.  Multiobjective Particle Swarm Optimization Using Fuzzy Logic , 2011, ICCCI.

[23]  P. Debré,et al.  CD2 triggering stimulates the formation of platelet-activating factor-acether from alkyl-arachidonoyl-glycerophosphocholine in a human CD4+ T lymphocyte clone. , 1992, Journal of immunology.

[24]  E. Boerwinkle,et al.  Erratum to: A causal network analysis in an observational study identifies metabolomics pathways influencing plasma triglyceride levels , 2016, Metabolomics.

[25]  A. Mero.  Leucine Supplementation and Intensive Training , 1999, Sports medicine.

[26]  D. Rubin.  Causal Inference Using Potential Outcomes , 2005 .

[27]  C. Zouboulis,et al.  Involvement of PPARgamma in oxidative stress-mediated prostaglandin E(2) production in SZ95 human sebaceous gland cells. , 2006, The Journal of investigative dermatology.

[28]  M. Baiocchi,et al.  Instrumental variable methods for causal inference , 2014, Statistics in medicine.

[29]  A. Dawid.  FUNDAMENTALS OF STATISTICAL CAUSALITY , 2007 .

[30]  Masatsugu Yamamoto,et al.  Gene-Metabolite Expression in Blood Can Discriminate Allergen-Induced Isolated Early from Dual Asthmatic Responses , 2013, PloS one.

[31]  M. Wall,et al.  Design of gene circuits: lessons from bacteria , 2004, Nature Reviews Genetics.

[32]  Ahmad Samiei,et al.  Generating a robust statistical causal structure over 13 cardiovascular disease risk factors using genomics data , 2016, J. Biomed. Informatics.

[33]  Eric Boerwinkle,et al.  A causal network analysis in an observational study identifies metabolomics pathways influencing plasma triglyceride levels , 2016, Metabolomics.

[34]  H. Yazdani,et al.  New similarity functions , 2016, 2016 Third International Conference on Artificial Intelligence and Pattern Recognition (AIPR).

[35]  David B. Dunson,et al.  A hybrid bayesian approach for genome-wide association studies on related individuals , 2015, Bioinform..