Clinical outcomes in patients with atrial fibrillation and frailty: insights from the ENGAGE AF-TIMI 48 trial

[1]  K. Rockwood,et al.  Atrial fibrillation and oral anticoagulation in older people with frailty: a nationwide primary care electronic health records cohort study. , 2021, Age and ageing.

[2]  C. Gale,et al.  Clinical and budget impacts of changes in oral anticoagulation prescribing for atrial fibrillation , 2020, Heart.

[3]  G. Lip,et al.  Low-Dose Edoxaban in Very Elderly Patients with Atrial Fibrillation. , 2020, The New England journal of medicine.

[4]  Jeroen J. Bax,et al.  2020 ESC Guidelines for the diagnosis and management of atrial fibrillation developed in collaboration with the European Association of Cardio-Thoracic Surgery (EACTS). , 2020, European heart journal.

[5]  K. Walters,et al.  New Horizons in the use of routine data for ageing research , 2020, Age and ageing.

[6]  S. Yusuf,et al.  Accumulation of Deficits as a Key Risk Factor for Cardiovascular Morbidity and Mortality: A Pooled Analysis of 154 000 Individuals , 2020, Journal of the American Heart Association.

[7]  Panos Vardas,et al.  European Society of Cardiology: Cardiovascular Disease Statistics 2019. , 2019, European heart journal.

[8]  L. Fried,et al.  Frailty: implications for clinical practice and public health , 2019, The Lancet.

[9]  Y. Balabanova,et al.  Appropriateness of initial dose of non-vitamin K antagonist oral anticoagulants in patients with non-valvular atrial fibrillation in the UK , 2019, BMJ Open.

[10]  Hugh Calkins,et al.  Correction to: 2019 AHA/ACC/HRS Focused Update of the 2014 AHA/ACC/HRS Guideline for the Management of Patients With Atrial Fibrillation: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines and the Heart Rhythm Society. , 2019, Circulation.

[11]  W. Aronow,et al.  Meta-Analysis of Direct-Acting Oral Anticoagulants Compared With Warfarin in Patients >75 Years of Age. , 2019, The American journal of cardiology.

[12]  S. Hägg,et al.  The frailty index is a predictor of cause-specific mortality independent of familial effects from midlife onwards: a large cohort study , 2019, BMC Medicine.

[13]  K. Rockwood,et al.  Age-related deficit accumulation and the diseases of ageing , 2019, Mechanisms of Ageing and Development.

[14]  Hugh Calkins,et al.  2019 AHA/ACC/HRS Focused Update of the 2014 AHA/ACC/HRS Guideline for the Management of Patients With Atrial Fibrillation: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines and the Heart Rhythm Society. , 2019, Heart rhythm.

[15]  C. Gale,et al.  Management of atrial fibrillation for older people with frailty: a systematic review and meta-analysis , 2018, Age and ageing.

[16]  K. Rockwood,et al.  Fifteen years of progress in understanding frailty and health in aging , 2018, BMC Medicine.

[17]  L. Cahill,et al.  Frailty, nutrition-related parameters, and mortality across the adult age spectrum , 2018, BMC Medicine.

[18]  F. Matthews,et al.  Frailty trajectories to identify end of life: a longitudinal population-based study , 2018, BMC Medicine.

[19]  R. West,et al.  A 10 year study of hospitalized atrial fibrillation-related stroke in England and its association with uptake of oral anticoagulation , 2018, European heart journal.

[20]  J. Cowan,et al.  Regional variation in anticoagulation and clinical outcomes: scope for improvement. , 2018, European heart journal. Quality of care & clinical outcomes.

[21]  G. Lip,et al.  Editor’s Choice - Frailty and the management of patients with acute cardiovascular disease: A position paper from the Acute Cardiovascular Care Association , 2018, European heart journal. Acute cardiovascular care.

[22]  C. Bates,et al.  Development and validation of an electronic frailty index using routine primary care electronic health record data , 2017, Age and ageing.

[23]  I. Palacios,et al.  Frailty in Older Adults Undergoing Aortic Valve Replacement: The FRAILTY-AVR Study. , 2017, Journal of the American College of Cardiology.

[24]  James R. Powell,et al.  Characterizing Frailty Status in the Systolic Blood Pressure Intervention Trial. , 2016, The journals of gerontology. Series A, Biological sciences and medical sciences.

[25]  John Young,et al.  Development and validation of an electronic frailty index using routine primary care electronic health record data , 2016, Age and ageing.

[26]  A. Mitnitski,et al.  Standard laboratory tests to identify older adults at increased risk of death , 2014, BMC Medicine.

[27]  I. Lang,et al.  Frailty, financial resources and subjective well-being in later life. , 2014, Archives of gerontology and geriatrics.

[28]  Daniel E Forman,et al.  Frailty assessment in the cardiovascular care of older adults. , 2014, Journal of the American College of Cardiology.

[29]  E. Antman,et al.  Edoxaban versus warfarin in patients with atrial fibrillation. , 2013, The New England journal of medicine.

[30]  Thomas Wilke,et al.  Incidence and prevalence of atrial fibrillation: an analysis based on 8.3 million patients. , 2013, Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology.

[31]  S. Iliffe,et al.  Frailty in elderly people , 2013, The Lancet.

[32]  C. Gale,et al.  The use of anticoagulants in the management of atrial fibrillation among general practices in England , 2013, Heart.

[33]  Rahul Wadke,et al.  Atrial fibrillation. , 2022, Disease-a-month : DM.

[34]  G. Lip,et al.  Atrial fibrillation , 2012, The Lancet.

[35]  Chris Dyer,et al.  Improving recruitment of older people to research through good practice. , 2011, Age and ageing.

[36]  D. Atar,et al.  Apixaban versus warfarin in patients with atrial fibrillation. , 2011, The New England journal of medicine.

[37]  G. Breithardt,et al.  Rivaroxaban versus warfarin in nonvalvular atrial fibrillation. , 2011, The New England journal of medicine.

[38]  R. Troughton,et al.  Rivaroxaban versus warfarin in nonvalvular atrial fibrillation. , 2011, The New England journal of medicine.

[39]  E. Antman,et al.  Evaluation of the novel factor Xa inhibitor edoxaban compared with warfarin in patients with atrial fibrillation: design and rationale for the Effective aNticoaGulation with factor xA next GEneration in Atrial Fibrillation-Thrombolysis In Myocardial Infarction study 48 (ENGAGE AF-TIMI 48). , 2010, American heart journal.

[40]  S. Cole,et al.  Generalizing evidence from randomized clinical trials to target populations: The ACTG 320 trial. , 2010, American journal of epidemiology.

[41]  D. Goldberg,et al.  Disparate inclusion of older adults in clinical trials: priorities and opportunities for policy and practice change. , 2010, American journal of public health.

[42]  S. Yusuf,et al.  Dabigatran versus warfarin in patients with atrial fibrillation. , 2009, The New England journal of medicine.

[43]  T. Gill,et al.  A standard procedure for creating a frailty index , 2008, BMC geriatrics.

[44]  A. Mitnitski,et al.  A comparison of two approaches to measuring frailty in elderly people. , 2007, The journals of gerontology. Series A, Biological sciences and medical sciences.

[45]  M. Aguilar,et al.  Meta-analysis: Antithrombotic Therapy to Prevent Stroke in Patients Who Have Nonvalvular Atrial Fibrillation , 2007, Annals of Internal Medicine.

[46]  T. Strandberg,et al.  Frailty in elderly people , 2007, The Lancet.

[47]  A. Mitnitski,et al.  Going from bad to worse: A stochastic model of transitions in deficit accumulation, in relation to mortality , 2006, Mechanisms of Ageing and Development.

[48]  J. Cox,et al.  Relative Fitness and Frailty of Elderly Men and Women in Developed Countries and Their Relationship with Mortality , 2005, Journal of the American Geriatrics Society.

[49]  S. Schulman,et al.  Definition of major bleeding in clinical investigations of antihemostatic medicinal products in non‐surgical patients , 2005, Journal of thrombosis and haemostasis : JTH.

[50]  Hilde van der Togt,et al.  Publisher's Note , 2003, J. Netw. Comput. Appl..