Optical coherence tomography as a promising imaging tool for brain investigations.

This paper will review the newest results and directions for the usage of optical coherence tomography as an imaging tool for brain studies, focusing mostly on a rodent model. Together with state of the art in the field, based on some of the most recent work, this paper will include a brief look on some results obtained by our group. Brain injuries and stroke data obtained by optical coherence tomography analyzing will be presented as a possibility of detection and evaluation for affected tissue, using this imaging system.

[1]  A. Fercher,et al.  Optical coherence tomography - principles and applications , 2003 .

[2]  Yu Chen,et al.  Effects of axial resolution improvement on optical coherence tomography (OCT) imaging of gastrointestinal tissues. , 2008, Optics express.

[3]  C. Baudouin,et al.  [Imaging of the iridocorneal angle in glaucoma]. , 2013, Journal francais d'ophtalmologie.

[4]  Kang Zhang,et al.  Real-time intraoperative full-range complex FD-OCT guided cerebral blood vessel identification and brain tumor resection in neurosurgery , 2011, BiOS.

[5]  Philip P. Chen,et al.  Evaluation of the anterior chamber angle in glaucoma: a report by the american academy of ophthalmology. , 2013, Ophthalmology.

[6]  A. Labbé,et al.  Imagerie de l’angle iridocornéen dans le glaucome , 2013 .

[7]  A. Rezai,et al.  A feasibility study of optical coherence tomography for guiding deep brain probes , 2006, Journal of Neuroscience Methods.

[8]  Harsha Radhakrishnan,et al.  Compartment-resolved Imaging of Cortical Functional Hyperemia with Oct Angiography References and Links , 2022 .

[9]  C. Kessler,et al.  beta-Amyloid precursor protein and ss-amyloid peptide immunoreactivity in the rat brain after middle cerebral artery occlusion: effect of age. , 1998, Stroke.

[10]  Tibo Gerriets,et al.  Complications and Pitfalls in Rat Stroke Models for Middle Cerebral Artery Occlusion: A Comparison Between the Suture and the Macrosphere Model Using Magnetic Resonance Angiography , 2004, Stroke.

[11]  Michael V. Sivak,et al.  Gastrointestinal optical coherence tomography , 2003 .

[12]  L. Zagrean,et al.  Sleep deprivation attenuates experimental stroke severity in rats , 2010, Experimental Neurology.

[13]  H. Barnett STROKE PREVENTION IN THE ELDERLY , 2002, Clinical and experimental hypertension.

[14]  G. Gelikonov,et al.  Optical coherence tomography of the esophagus and proximal stomach in health and disease , 2001, American Journal of Gastroenterology.

[15]  A. Popa-Wagner,et al.  Cellular and molecular mechanisms underlying neurorehabilitation after stroke in aged subjects. , 2008, Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie.

[16]  Sava Sakadžić,et al.  Multiparametric, Longitudinal Optical Coherence Tomography Imaging Reveals Acute Injury and Chronic Recovery in Experimental Ischemic Stroke , 2013, PloS one.

[17]  G. Gelikonov,et al.  In vivo endoscopic OCT imaging of precancer and cancer states of human mucosa. , 1997, Optics express.

[18]  T. Yanagida,et al.  Optical coherence tomography reveals in vivo cortical plasticity of adult mice in response to peripheral neuropathic pain , 2006, Neuroscience Letters.

[19]  C. Kessler,et al.  Accelerated Glial Reactivity to Stroke in Aged Rats Correlates with Reduced Functional Recovery , 2003, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

[20]  Dirk Faber,et al.  Functional optical coherence tomography : spatially resolved measurements of optical properties , 2005 .

[21]  J. Fujimoto,et al.  Optical Coherence Tomography , 1991, LEOS '92 Conference Proceedings.

[22]  M. Rausch,et al.  Recovery and brain reorganization after stroke in adult and aged rats , 2005, Annals of neurology.

[23]  David A Boas,et al.  Depth-resolved microscopy of cortical hemodynamics with optical coherence tomography. , 2009, Optics letters.

[24]  Anna Devor,et al.  Optical coherence tomography (OCT) reveals depth-resolved dynamics during functional brain activation , 2009, Journal of Neuroscience Methods.

[25]  J. Fujimoto,et al.  Optical coherence tomography for optical biopsy. Properties and demonstration of vascular pathology. , 1996, Circulation.

[26]  A. Fercher,et al.  In vivo optical coherence tomography. , 1993, American journal of ophthalmology.

[27]  M. Brezinski Optical Coherence Tomography: Principles and Applications , 2006 .

[28]  A. Boccara,et al.  Single myelin fiber imaging in living rodents without labeling by deep optical coherence microscopy. , 2011, Journal of biomedical optics.

[29]  J. Welzel Optical coherence tomography in dermatology: a review , 2001, Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging.

[30]  Alan D. Lopez,et al.  Global and regional burden of disease and risk factors, 2001: systematic analysis of population health data , 2006, The Lancet.

[31]  Ruikang K. Wang,et al.  Theory, developments and applications of optical coherence tomography , 2005 .

[32]  S A Boppart,et al.  Optical coherence tomography for neurosurgical imaging of human intracortical melanoma. , 1998, Neurosurgery.

[33]  Satoko Kawauchi,et al.  Light-scattering signal may indicate critical time zone to rescue brain tissue after hypoxia. , 2011, Journal of biomedical optics.

[34]  L. Mogoantă,et al.  Study of vascular microdensity in areas of cerebral ischemia on experimental model. , 2010, Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie.

[35]  L. Mogoantă,et al.  Strategies to improve post-stroke behavioral recovery in aged subjects. , 2009, Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie.

[36]  P. Calabresi,et al.  Optical Coherence Tomography (OCT): Imaging the Visual Pathway as a Model for Neurodegeneration , 2010, Neurotherapeutics.

[37]  A. C. M. Ercolin,et al.  The use of animal models for stroke research: a review. , 2011, Comparative medicine.

[38]  C. Grimm,et al.  In vivo assessment of rodent retinal structure using spectral domain optical coherence tomography. , 2012, Advances in experimental medicine and biology.

[39]  J. Fujimoto,et al.  In vivo retinal imaging by optical coherence tomography. , 1993, Optics letters.

[40]  Edmund Koch,et al.  Optical coherence tomography in biomedical research , 2011, Analytical and bioanalytical chemistry.

[41]  James G Fujimoto,et al.  Three-dimensional and C-mode OCT imaging with a compact, frequency swept laser source at 1300 nm. , 2005, Optics express.

[42]  R. Vink,et al.  Animal models of mild and severe TBI: what have we learned in the past 30 years? , 2012 .

[43]  A. Saftoiu,et al.  Optical coherence tomography and Doppler optical coherence tomography in the gastrointestinal tract. , 2011, World journal of gastroenterology.

[44]  Mari Mino-Kenudson,et al.  Identifying intestinal metaplasia at the squamocolumnar junction by using optical coherence tomography. , 2007, Gastrointestinal endoscopy.

[45]  Zhongping Chen,et al.  Gastrointestinal optical coherence tomography: clinical applications, limitations, and research priorities. , 2009, Gastrointestinal endoscopy clinics of North America.

[46]  P. Wolf,et al.  The lifetime risk of stroke: estimates from the Framingham Study. , 2006, Stroke.

[47]  Adolf Friedrich Fercher,et al.  Optical coherence tomography - development, principles, applications. , 2010, Zeitschrift fur medizinische Physik.

[48]  V. Srinivasan,et al.  Optical coherence microscopy for deep tissue imaging of the cerebral cortex with intrinsic contrast , 2012, Optics express.