A mathematical and numerical framework for ultrasonically-induced Lorentz force electrical impedance tomography☆

We provide a mathematical analysis and a numerical framework for Lorentz force electrical conductivity imaging. Ultrasonic vibration of a tissue in the presence of a static magnetic eld induces an electrical current by the Lorentz force. This current can be detected by electrodes placed around the tissue; it is proportional to the velocity of the ultrasonic pulse, but depends nonlinearly on the conductivity distribution. The imaging problem is to reconstruct the conductivity distribution from measurements of the induced current. To solve this nonlinear inverse problem, we rst make use of a virtual potential to relate explicitly the current measurements to the conductivity distribution and the velocity of the ultrasonic pulse. Then, by applying a Wiener lter to the measured data, we reduce the problem to imaging the conductivity from an internal electric current density. We rst introduce an optimal control method for solving such a problem. A new direct reconstruction scheme involving a partial dierential equation is then proposed based on viscositytype regularization to a transport equation satised by the current density eld. We prove that solving such an equation yields the true conductivity distribution as the regularization parameter approaches zero. We also test both schemes numerically in the presence of measurement noise, quantify their stability and resolution, and compare their performance.

[1]  L. Kunyansky,et al.  A mathematical model and inversion procedure for magneto-acousto-electric tomography , 2011, 1108.0376.

[2]  P. Nistri,et al.  On Discontinuous Differential Equations , 2009 .

[3]  Bradley J. Roth,et al.  Ultrasonically-induced Lorentz force tomography , 2009, Medical & Biological Engineering & Computing.

[4]  David Isaacson,et al.  Electrical Impedance Tomography , 1999, SIAM Rev..

[5]  Jérôme Fehrenbach,et al.  Imaging by Modification: Numerical Reconstruction of Local Conductivities from Corresponding Power Density Measurements , 2009, SIAM J. Imaging Sci..

[6]  Eung Je Woo,et al.  Magnetic Resonance Electrical Impedance Tomography (MREIT) , 2011, SIAM Rev..

[7]  Bradley J. Roth,et al.  The potential induced in anisotropic tissue by the ultrasonically-induced Lorentz force , 2008, Medical & Biological Engineering & Computing.

[8]  Otmar Scherzer,et al.  Impedance-Acoustic Tomography , 2008, SIAM J. Appl. Math..

[9]  Stéphane Mallat,et al.  A Wavelet Tour of Signal Processing - The Sparse Way, 3rd Edition , 2008 .

[10]  Pride,et al.  Governing equations for the coupled electromagnetics and acoustics of porous media. , 1994, Physical review. B, Condensed matter.

[11]  Habib Ammari,et al.  Mathematical models and reconstruction methods in magneto-acoustic imaging , 2009, European Journal of Applied Mathematics.

[12]  K. Foster,et al.  Dielectric properties of tissues and biological materials: a critical review. , 1989, Critical reviews in biomedical engineering.

[13]  Otomar Hájek,et al.  Discontinuous differential equations, II , 1979 .

[14]  Bradley J Roth,et al.  The role of magnetic forces in biology and medicine , 2011, Experimental biology and medicine.

[15]  Xu Li,et al.  Imaging Electrical Impedance From Acoustic Measurements by Means of Magnetoacoustic Tomography With Magnetic Induction (MAT-MI) , 2007, IEEE Transactions on Biomedical Engineering.

[16]  J. Shah,et al.  Hall effect imaging , 1998, IEEE Transactions on Biomedical Engineering.

[17]  Eung Je Woo,et al.  Mathematical framework for a new microscopic electrical impedance tomography system , 2011 .

[18]  Habib Ammari,et al.  An Introduction to Mathematics of Emerging Biomedical Imaging , 2008 .

[19]  O. Scherzer,et al.  Hybrid tomography for conductivity imaging , 2011, 1112.2958.

[20]  Josselin Garnier,et al.  Spectroscopic imaging of a dilute cell suspension , 2013, 1310.1292.

[21]  Josselin Garnier,et al.  Resolution and stability analysis in acousto-electric imaging , 2012 .

[22]  Aaas News,et al.  Book Reviews , 1893, Buffalo Medical and Surgical Journal.

[23]  T Iritani,et al.  A study of the electrical bio-impedance of tumors. , 1993, Journal of investigative surgery : the official journal of the Academy of Surgical Research.

[24]  Bin He,et al.  Magnetoacoustic Tomography With Magnetic Induction: Bioimepedance Reconstruction Through Vector Source Imaging , 2013, IEEE Transactions on Medical Imaging.

[25]  F. Dunn,et al.  Comprehensive compilation of empirical ultrasonic properties of mammalian tissues. , 1978, The Journal of the Acoustical Society of America.

[26]  Ohin Kwon,et al.  Equipotential line method for magnetic resonance electrical impedance tomography , 2002 .

[27]  Eric Bonnetier,et al.  Electrical Impedance Tomography by Elastic Deformation , 2008, SIAM J. Appl. Math..

[28]  Jean-Yves Chapelon,et al.  Lorentz force electrical impedance tomography , 2013, 1402.2573.

[29]  Ohin Kwon,et al.  T-Scan Electrical Impedance Imaging System for Anomaly Detection , 2004, SIAM J. Appl. Math..