ShinyGPA: An interactive visualization toolkit for investigating pleiotropic architecture using GWAS datasets
暂无分享,去创建一个
Gary Hardiman | Dongjun Chung | Emma Kortemeier | Paula S Ramos | Kelly J Hunt | Hang J Kim | Hang J. Kim | Emma Kortemeier | P. Ramos | K. Hunt | G. Hardiman | Dongjun Chung | Paula S. Ramos
[1] J. Medalie,et al. Major factors in the development of diabetes mellitus in 10,000 men. , 1975, Archives of internal medicine.
[2] E. Barrett-Connor,et al. Cardiovascular disease risk factors prior to the diagnosis of impaired glucose tolerance and non-insulin-dependent diabetes mellitus in a community of older adults. , 1990, American journal of epidemiology.
[3] B. Howard,et al. Plasma lipoproteins and incidence of non-insulin-dependent diabetes mellitus in Pima Indians: protective effect of HDL cholesterol in women. , 1997, Atherosclerosis.
[4] M. Laakso,et al. Mortality from coronary heart disease in subjects with type 2 diabetes and in nondiabetic subjects with and without prior myocardial infarction. , 1998, The New England journal of medicine.
[5] J. Tenenbaum,et al. A global geometric framework for nonlinear dimensionality reduction. , 2000, Science.
[6] Teven,et al. MORTALITY FROM CORONARY HEART DISEASE IN SUBJECTS WITH TYPE 2 DIABETES AND IN NONDIABETIC SUBJECTS WITH AND WITHOUT PRIOR MYOCARDIAL INFARCTION , 2000 .
[7] Walter C Willett,et al. Elevated risk of cardiovascular disease prior to clinical diagnosis of type 2 diabetes. , 2002, Diabetes care.
[8] Ken Williams,et al. Elevated Carotid Artery Intima-Media Thickness Levels in Individuals Who Subsequently Develop Type 2 Diabetes , 2003, Arteriosclerosis, thrombosis, and vascular biology.
[9] Sue Povey,et al. Gene map of the extended human MHC , 2004, Nature Reviews Genetics.
[10] H. Lebovitz. Insulin resistance – a common link between type 2 diabetes and cardiovascular disease , 2006, Diabetes, obesity & metabolism.
[11] M. Laakso,et al. Cardiovascular disease risk factors as predictors of Type 2 (non-insulin-dependent) diabetes mellitus in elderly subjects , 1993, Diabetologia.
[12] P. Whincup,et al. Associations of adiponectin with metabolic and vascular risk parameters in the British Regional Heart Study reveal stronger links to insulin resistance-related than to coronory heart disease risk-related parameters , 2007, International Journal of Obesity.
[13] R. Esper,et al. Endothelial dysfunction in normal and abnormal glucose metabolism. , 2008, Advances in cardiology.
[14] Francis S Collins,et al. A HapMap harvest of insights into the genetics of common disease. , 2008, The Journal of clinical investigation.
[15] R. Esper,et al. Endothelial dysfunction in normal and abnormal glucose metabolism. , 2008 .
[16] P. Visscher,et al. Common polygenic variation contributes to risk of schizophrenia and bipolar disorder , 2009, Nature.
[17] F. Collins,et al. Potential etiologic and functional implications of genome-wide association loci for human diseases and traits , 2009, Proceedings of the National Academy of Sciences.
[18] Jing Cui,et al. Genome-wide association study meta-analysis identifies seven new rheumatoid arthritis risk loci , 2010, Nature Genetics.
[19] Tariq Ahmad,et al. Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci , 2010, Nature Genetics.
[20] Tanya M. Teslovich,et al. Biological, Clinical, and Population Relevance of 95 Loci for Blood Lipids , 2010, Nature.
[21] Thomas W. Mühleisen,et al. Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease , 2011, Nature Genetics.
[22] Raphael Zidovetzki,et al. A Comprehensive Analysis of Shared Loci between Systemic Lupus Erythematosus (SLE) and Sixteen Autoimmune Diseases Reveals Limited Genetic Overlap , 2011, PLoS genetics.
[23] Tom R. Gaunt,et al. Genetic Variants in Novel Pathways Influence Blood Pressure and Cardiovascular Disease Risk , 2011, Nature.
[24] Christian Gieger,et al. Genetic Variants in Novel Pathways Influence Blood Pressure and Cardiovascular Disease Risk , 2011, Nature.
[25] F. Agakov,et al. Abundant pleiotropy in human complex diseases and traits. , 2011, American journal of human genetics.
[26] Tariq Ahmad,et al. Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47 , 2011, Nature Genetics.
[27] Tanya M. Teslovich,et al. Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes , 2012, Nature Genetics.
[28] Jianxin Shi,et al. Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs , 2013, Nature Genetics.
[29] M. McCarthy,et al. Improved detection of common variants associated with schizophrenia by leveraging pleiotropy with cardiovascular-disease risk factors. , 2013, American journal of human genetics.
[30] M. Daly,et al. Identification of risk loci with shared effects on five major psychiatric disorders: a genome-wide analysis , 2013, The Lancet.
[31] Hongyu Zhao,et al. GPA: A Statistical Approach to Prioritizing GWAS Results by Integrating Pleiotropy and Annotation , 2014, PLoS genetics.
[32] M. Daly,et al. Genetic and Epigenetic Fine-Mapping of Causal Autoimmune Disease Variants , 2014, Nature.
[33] P. Ramos,et al. GPA-MDS: A Visualization Approach to Investigate Genetic Architecture among Phenotypes Using GWAS Results , 2016, International journal of genomics.