Chemical Respiratory Allergy: Opportunities for Hazard Identification and Characterisation
暂无分享,去创建一个
Emanuela Corsini | Paul Cullinan | Raymond Agius | Thomas Hartung | Costanza Rovida | Frieke Kuper | Ian Kimber | David A Basketter | Erwin Roggen | P. Cullinan | C. Rovida | T. Hartung | D. Basketter | R. Agius | E. Corsini | F. Kuper | I. Kimber | P. Maestrelli | R. Dearman | Rebecca J Dearman | Piero Maestrelli | E. Roggen | E. Giménez-Arnau | Leona Greenwell | Elena Gimenez-Arnau | Leona Greenwell
[1] Silvia Casati,et al. The Development of Novel Approaches to the Identification of Chemical and Protein Respiratory Allergens , 2008, Alternatives to laboratory animals : ATLA.
[2] Silvia Casati,et al. Chemical reactivity measurement and the predicitve identification of skin sensitisers. The report and recommendations of ECVAM Workshop 64. , 2008, Alternatives to laboratory animals : ATLA.
[3] I. Sipes,et al. Chemical respiratory allergy and occupational asthma: what are the key areas of uncertainty? , 2008, Journal of applied toxicology : JAT.
[4] G Frank Gerberick,et al. Quantification of chemical peptide reactivity for screening contact allergens: a classification tree model approach. , 2007, Toxicological sciences : an official journal of the Society of Toxicology.
[5] Heimo Breiteneder,et al. Nomenclature and structural biology of allergens. , 2007, The Journal of allergy and clinical immunology.
[6] Erwin L Roggen,et al. Respiratory immunotoxicity: an in vitro assessment. , 2006, Toxicology in vitro : an international journal published in association with BIBRA.
[7] M. Selgrade,et al. Inconsistencies between cytokine profiles, antibody responses, and respiratory hyperresponsiveness following dermal exposure to isocyanates. , 2006, Toxicological sciences : an official journal of the Society of Toxicology.
[8] P. Cullinan,et al. Outcome of occupational asthma after cessation of exposure: a systematic review , 2006, Thorax.
[9] H. Sakaguchi,et al. Development of an in vitro skin sensitization test using human cell lines; human Cell Line Activation Test (h-CLAT). II. An inter-laboratory study of the h-CLAT. , 2006, Toxicology in vitro : an international journal published in association with BIBRA.
[10] H. Sakaguchi,et al. Development of an in vitro skin sensitization test using human cell lines: the human Cell Line Activation Test (h-CLAT). I. Optimization of the h-CLAT protocol. , 2006, Toxicology in vitro : an international journal published in association with BIBRA.
[11] N. Bloksma,et al. Trimellitic anhydride-conjugated serum albumin activates rat alveolar macrophages in vitro , 2006, Journal of occupational medicine and toxicology.
[12] S. Skerfving,et al. Ocular and airway symptoms related to organic acid anhydride exposure – a prospective study , 2006, Allergy.
[13] I. Kimber,et al. Assessing the potential to induce respiratory hypersensitivity. , 2006, Toxicological sciences : an official journal of the Society of Toxicology.
[14] I. Fabre,et al. The cytokine-dependent MUTZ-3 cell line as an in vitro model for the screening of contact sensitizers. , 2006, Toxicology and applied pharmacology.
[15] C. Borrebaeck,et al. Interactions between dendritic cells and epithelial cells in allergic disease. , 2006, Toxicology letters.
[16] J. Malo,et al. An ATS/ERS report: 100 key questions and needs in occupational asthma , 2006, European Respiratory Journal.
[17] P. Cullinan,et al. Is occupational asthma to diisocyanates a non-IgE-mediated disease? , 2006, The Journal of allergy and clinical immunology.
[18] M. Chan-yeung,et al. Asthma in the Workplace, Third Edition , 2006 .
[19] G. Storm,et al. Alveolar macrophages suppress non-specific inflammation caused by inhalation challenge with trimellitic anhydride conjugated to albumin , 2006, Archives of Toxicology.
[20] S. Vieths,et al. A novel approach for investigation of specific and cross-reactive IgE epitopes on Bet v 1 and homologous food allergens in individual patients. , 2006, Molecular immunology.
[21] S. Gibbs,et al. CXCL8 secretion by dendritic cells predicts contact allergens from irritants. , 2006, Toxicology in vitro : an international journal published in association with BIBRA.
[22] J. Lepoittevin. Metabolism versus chemical transformation or pro‐ versus prehaptens? , 2006, Contact dermatitis.
[23] Erwin L Roggen,et al. Recent Developments with B-Cell Epitope Identification for Predictive Studies , 2006, Journal of immunotoxicology.
[24] Ian Kimber,et al. Compilation of Historical Local Lymph Node Data for Evaluation of Skin Sensitization Alternative Methods , 2005, Dermatitis : contact, atopic, occupational, drug.
[25] G Frank Gerberick,et al. Interactions of contact allergens with dendritic cells: opportunities and challenges for the development of novel approaches to hazard assessment. , 2005, Toxicological sciences : an official journal of the Society of Toxicology.
[26] Petra S. Kern,et al. Skin Sensitization: Modeling Based on Skin Metabolism Simulation and Formation of Protein Conjugates , 2005, International journal of toxicology.
[27] Ian Kimber,et al. Impact of Cutaneous IL-10 on Resident Epidermal Langerhans’ Cells and the Development of Polarized Immune Responses , 2005, The Journal of Immunology.
[28] M. Karol,et al. Development of an information-intensive structure–activity relationship model and its application to human respiratory chemical sensitizers , 2005, SAR and QSAR in environmental research.
[29] Henk Van Loveren,et al. Assessment of potency of allergenic activity of low molecular weight compounds based on IL-1alpha and IL-18 production by a murine and human keratinocyte cell line. , 2005, Toxicology.
[30] S. Kohno,et al. Delayed-Type Asthmatic Response Induced by Repeated Intratracheal Exposure to Toluene-2,4-Diisocyanate in Guinea Pigs , 2005, International Archives of Allergy and Immunology.
[31] I. Kimber,et al. What makes a chemical a respiratory sensitizer? , 2005, Current opinion in allergy and clinical immunology.
[32] Ulrich Mohr,et al. Experimental approaches to evaluate respiratory allergy in animal models. , 2005, Experimental and Toxicological Pathology.
[33] M. Willart,et al. In vivo depletion of lung CD11c+ dendritic cells during allergen challenge abrogates the characteristic features of asthma , 2005, The Journal of experimental medicine.
[34] R. Elton,et al. Relationship between chemical structure and the occupational asthma hazard of low molecular weight organic compounds , 2005, Occupational and Environmental Medicine.
[35] R. Smialowicz,et al. Cytokine mRNA profiles for isocyanates with known and unknown potential to induce respiratory sensitization. , 2005, Toxicology.
[36] Paul J Thornalley,et al. Peptide Mapping Identifies Hotspot Site of Modification in Human Serum Albumin by Methylglyoxal Involved in Ligand Binding and Esterase Activity* , 2005, Journal of Biological Chemistry.
[37] N. Kitteringham,et al. Selective Haptenation of Cellular or Extracellular Protein by Chemical Allergens: Association with Cytokine Polarization , 2005 .
[38] Valérie Zuang,et al. Dendritic Cells as a Tool for the Predictive Identification of Skin Sensitisation Hazard , 2005, Alternatives to laboratory animals : ATLA.
[39] Peter Gehr,et al. A three-dimensional cellular model of the human respiratory tract to study the interaction with particles. , 2005, American journal of respiratory cell and molecular biology.
[40] L. Bloemen,et al. Repeated Inhalation Challenge with Diphenylmethane-4,4′-Diisocyanate in Brown Norway Rats Leads to a Time-Related Increase of Neutrophils in Bronchoalveolar Lavage After Topical Induction , 2005, Inhalation toxicology.
[41] J. Pauluhn. Brown Norway Rat Asthma Model of Diphenylmethane 4,4′-Diisocyanate , 2005, Inhalation toxicology.
[42] G Frank Gerberick,et al. Development of a peptide reactivity assay for screening contact allergens. , 2004, Toxicological sciences : an official journal of the Society of Toxicology.
[43] P. Paré,et al. The use and misuse of Penh in animal models of lung disease. , 2004, American journal of respiratory cell and molecular biology.
[44] D. Basketter,et al. Effect of glutathione on the covalent binding of the 13C-labeled skin sensitizer 5-chloro-2-methylisothiazol-3-one to human serum albumin: identification of adducts by nuclear magnetic resonance, matrix-assisted laser desorption/ionization mass spectrometry, and nanoelectrospray tandem mass spectrom , 2004, Chemical Research in Toxicology.
[45] J. Ceuppens,et al. Respiratory response to toluene diisocyanate depends on prior frequency and concentration of dermal sensitization in mice. , 2004, Toxicological sciences : an official journal of the Society of Toxicology.
[46] M. Peters-Golden. The alveolar macrophage: the forgotten cell in asthma. , 2004, American journal of respiratory cell and molecular biology.
[47] C. Akdis,et al. Immune Responses in Healthy and Allergic Individuals Are Characterized by a Fine Balance between Allergen-specific T Regulatory 1 and T Helper 2 Cells , 2004, The Journal of experimental medicine.
[48] N. Kaminski,et al. Allergic rhinitis induced by intranasal sensitization and challenge with trimellitic anhydride but not with dinitrochlorobenzene or oxazolone in A/J mice. , 2004, Toxicological sciences : an official journal of the Society of Toxicology.
[49] G Frank Gerberick,et al. Gene expression changes in peripheral blood-derived dendritic cells following exposure to a contact allergen. , 2004, Toxicology letters.
[50] C. Goebel,et al. Characterization of the sensitizing potential of chemicals by in vitro analysis of dendritic cell activation and skin penetration. , 2004, The Journal of investigative dermatology.
[51] D. Basketter,et al. Protein binding and metabolism influence the relative skin sensitization potential of cinnamic compounds. , 2004, Chemical research in toxicology.
[52] P. Siegel,et al. Asthmalike biphasic airway responses in Brown Norway rats sensitized by dermal exposure to dry trimellitic anhydride powder. , 2004, The Journal of allergy and clinical immunology.
[53] M. Epstein. Do Mouse Models of Allergic Asthma Mimic Clinical Disease? , 2004, International Archives of Allergy and Immunology.
[54] N. Bloksma,et al. Respiratory Allergy to Trimellitic Anhydride in Rats: Concentration-Response Relationships During Elicitation , 2004, Inhalation toxicology.
[55] J. Pauluhn. Respiratory hypersensitivity to trimellitic anhydride in Brown Norway rats: analysis of dose-response following topical induction and time course following repeated inhalation challenge. , 2003, Toxicology.
[56] B. Meade,et al. Dermal exposure to 3-amino-5-mercapto-1,2,4-triazole (AMT) induces sensitization and airway hyperreactivity in BALB/c mice. , 2003, Toxicological sciences : an official journal of the Society of Toxicology.
[57] A. Wisnewski,et al. Human γ/δ T-cell proliferation and IFN-γ production induced by hexamethylene diisocyanate , 2003 .
[58] Alan G. E. Wilson,et al. A multiple in silico program approach for the prediction of mutagenicity from chemical structure. , 2003, Mutation research.
[59] O. Vandenplas,et al. Pathogenesis of occupational asthma , 2003, European Respiratory Journal.
[60] N. Humphreys,et al. Methods for the identification of chemical respiratory allergens in rodents: comparisons of cytokine profiling with induced changes in serum IgE , 2003, Journal of applied toxicology : JAT.
[61] C. Griffiths,et al. Epidermal Langerhans cell migration and sensitisation to chemical allergens , 2003, APMIS : acta pathologica, microbiologica, et immunologica Scandinavica.
[62] P. Kalinski,et al. Double-stranded RNA-exposed human keratinocytes promote Th1 responses by inducing a Type-1 polarized phenotype in dendritic cells: role of keratinocyte-derived tumor necrosis factor alpha, type I interferons, and interleukin-18. , 2003, The Journal of investigative dermatology.
[63] A. Wisnewski,et al. Recent developments in diisocyanate asthma. , 2003, Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology.
[64] A. Wisnewski,et al. Differential roles for CD4 and CD8 T cells after diisocyanate sensitization: genetic control of TH2-induced lung inflammation. , 2003, The Journal of allergy and clinical immunology.
[65] D. Pritchard,et al. House dust mite Der p 1 downregulates defenses of the lung by inactivating elastase inhibitors. , 2003, American journal of respiratory cell and molecular biology.
[66] Kathleen Kreiss,et al. American Thoracic Society Statement: Occupational contribution to the burden of airway disease. , 2003, American journal of respiratory and critical care medicine.
[67] N. Bloksma,et al. Respiratory allergy and pulmonary irritation to trimellitic anhydride in Brown Norway rats. , 2003, Toxicology and applied pharmacology.
[68] C. Hansson,et al. Reactivity of Contact Allergenic Haptens to Amino Acid Residues in a Model Carrier Peptide, and Characterization of Formed Peptide-Hapten Adducts1 , 2003, Skin Pharmacology and Physiology.
[69] Y. Fukumori,et al. Peptide-binding assessment using mass spectrometry as a new screening method for skin sensitization. , 2003, The Journal of toxicological sciences.
[70] Neil Humphreys,et al. Chemical allergy: considerations for the practical application of cytokine profiling. , 2003, Toxicological sciences : an official journal of the Society of Toxicology.
[71] P. Jurs,et al. Development of binary classification of structural chromosome aberrations for a diverse set of organic compounds from molecular structure. , 2003, Chemical research in toxicology.
[72] I. Kimber,et al. Chemical respiratory allergy: role of IgE antibody and relevance of route of exposure. , 2002, Toxicology.
[73] I. Kimber,et al. Temporal changes in cytokine gene expression profiles induced in mice by trimellitic anhydride. , 2002, Toxicology letters.
[74] S. Aiba,et al. Evaluation of CD86 expression and MHC class II molecule internalization in THP-1 human monocyte cells as predictive endpoints for contact sensitizers. , 2002, Toxicology in vitro : an international journal published in association with BIBRA.
[75] I. Kimber,et al. Cytokine fingerprinting of chemical allergens: species comparisons and statistical analyses. , 2002, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.
[76] D. Nahm,et al. Longitudinal study of specific antibodies to toluene diisocyanate (TDI)-human serum albumin (HSA) conjugate in patients with TDI-induced asthma , 2002, The Korean journal of internal medicine.
[77] A. Goossens,et al. Occupational allergic contact dermatitis caused by isocyanates , 2002, Contact dermatitis.
[78] H. van Loveren,et al. Cytokine production induced by low-molecular-weight chemicals as a function of the stimulation index in a modified local lymph node assay: an approach to discriminate contact sensitizers from respiratory sensitizers. , 2002, Toxicology and applied pharmacology.
[79] I. Humphreys,et al. Interleukins 5 and 13 characterize immune responses to respiratory sensitizing acid anhydrides , 2002, Journal of applied toxicology : JAT.
[80] L. Boulet,et al. Diisocyanate antigen-stimulated monocyte chemoattractant protein-1 synthesis has greater test efficiency than specific antibodies for identification of diisocyanate asthma. , 2002, American journal of respiratory and critical care medicine.
[81] G Frank Gerberick,et al. Elucidating changes in surface marker expression of dendritic cells following chemical allergen treatment. , 2002, Toxicology and applied pharmacology.
[82] P. Siegel,et al. Dose‐response and time course of specific IgE and IgG after single and repeated topical skin exposure to dry trimellitic anhydride powder in a Brown Norway rat model , 2002, Allergy.
[83] D. Nahm,et al. Specific immunoglobulin E and immunoglobulin G antibodies to toluene diisocyanate‐human serum albumin conjugate: useful markers for predicting long‐term prognosis in toluene diisocyanate‐induced asthma , 2002, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.
[84] H. Norppa,et al. N-Acetyltransferase genotypes as modifiers of diisocyanate exposure-associated asthma risk. , 2002, Pharmacogenetics.
[85] R. Smialowicz,et al. Cytokine profiling for chemical sensitizers: application of the ribonuclease protection assay and effect of dose. , 2002, Toxicology and applied pharmacology.
[86] J. Pauluhn,et al. Respiratory hypersensitivity to trimellitic anhydride in Brown Norway Rats: a comparison of endpoints , 2002, Journal of applied toxicology : JAT.
[87] J. Pauluhn,et al. Respiratory hypersensitivity in guinea pigs sensitized to 1,6-hexamethylene diisocyanate (HDI): comparison of results obtained with the monomer and homopolymers of HDI. , 2002, Toxicology.
[88] M. Kool,et al. Hypersensitivity reactions in mouse airways after a single and a repeated hapten challenge , 2002, Inflammation Research.
[89] K. Higashi,et al. Assessment of preferential Th1 or Th2 induction by low-molecular-weight compounds using a reverse transcription-polymerase chain reaction method: comparison of two mouse strains, C57BL/6 and BALB/c. , 2001, Toxicology and applied pharmacology.
[90] P. Ulrich,et al. Cytokine expression profiles during murine contact allergy: T helper 2 cytokines are expressed irrespective of the type of contact allergen , 2001, Archives of Toxicology.
[91] J. Regal,et al. Trimellitic anhydride-induced eosinophilia in a mouse model of occupational asthma. , 2001, Toxicology and applied pharmacology.
[92] M D Barratt,et al. The computational prediction of toxicity. , 2001, Current opinion in chemical biology.
[93] B. Meade,et al. The determination of draining lymph node cell cytokine mRNA levels in BALB/c mice following dermal sodium lauryl sulfate, dinitrofluorobenzene, and toluene diisocyanate exposure. , 2001, Toxicology and applied pharmacology.
[94] I. Kimber,et al. Cytokine fingerprinting and hazard assessment of chemical respiratory allergy , 2001, Journal of applied toxicology : JAT.
[95] S. K. Lee,et al. Diverse profiles of specific IgE response to toluene diisocyanate (TDI)-human serum albumin conjugate in TDI-induced asthma patients. , 2001, Journal of Korean medical science.
[96] D. Hendrick. The world wide problem of occupational asthma , 2001, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.
[97] S. Meredith,et al. Isocyanate exposure and occupational asthma: a case-referent study , 2000, Occupational and environmental medicine.
[98] M. Desrosiers,et al. Epidemiology of occupational rhinitis: prevalence, aetiology and determinants , 2000, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.
[99] D. Leung,et al. Allergen sensitization through the skin induces systemic allergic responses. , 2000, The Journal of allergy and clinical immunology.
[100] E. Petsonk,et al. Asthma-like symptoms in wood product plant workers exposed to methylene diphenyl diisocyanate. , 2000, Chest.
[101] H. Tagami,et al. In vitro treatment of human transforming growth factor‐β1‐treated monocyte‐derived dendritic cells with haptens can induce the phenotypic and functional changes similar to epidermal Langerhans cells in the initiation phase of allergic contact sensitivity reaction , 2000, Immunology.
[102] I Kimber,et al. Investigation of induced changes in interleukin 1beta mRNA expression by cultured human dendritic cells as an in vitro approach to skin sensitization testing. , 2000, Toxicology in vitro : an international journal published in association with BIBRA.
[103] G. Liss,et al. Hospitalization among workers compensated for occupational asthma. , 2000, American journal of respiratory and critical care medicine.
[104] J. Pauluhn,et al. Respiratory sensitization to diphenyl-methane-4,4'-diisocyanate (MDI) in guinea pigs: impact of particle size on induction and elicitation of response. , 2000, Toxicological sciences : an official journal of the Society of Toxicology.
[105] G F Gerberick,et al. A skin sensitization risk assessment approach for evaluation of new ingredients and products. , 2000, American journal of contact dermatitis : official journal of the American Contact Dermatitis Society.
[106] I. Humphreys,et al. Characterization in mice of the immunological properties of five allergenic acid anhydrides , 2000, Journal of applied toxicology : JAT.
[107] D. Mannino. How much asthma is occupationally related? , 2000, Occupational medicine.
[108] I. Kimber,et al. REVIEWCytokines and chemokines in the initiation and regulation of epidermal Langerhans cell mobilization , 2000, The British journal of dermatology.
[109] M R Cullen,et al. Qualitative assessment of isocyanate skin exposure in auto body shops: a pilot study. , 2000, American journal of industrial medicine.
[110] I Kimber,et al. Local lymph node assay: validation assessment for regulatory purposes. , 2000, American journal of contact dermatitis : official journal of the American Contact Dermatitis Society.
[111] W. D. de Jong,et al. Assessment of preferential T-helper 1 or T-helper 2 induction by low molecular weight compounds using the local lymph node assay in conjunction with RT-PCR and ELISA for interferon-gamma and interleukin-4. , 2000, Toxicology and applied pharmacology.
[112] S. Tarlo,et al. Important issues in occupational asthma , 2000, Current opinion in pulmonary medicine.
[113] K. Torén,et al. How much adult asthma can be attributed to occupational factors? , 1999, The American journal of medicine.
[114] S. Tarlo. Diisocyanate sensitization and antibody production. , 1999, The Journal of allergy and clinical immunology.
[115] J. Lesage,et al. Specific IgG response to monomeric and polymeric diphenylmethane diisocyanate conjugates in subjects with respiratory reactions to isocyanates. , 1999, The Journal of allergy and clinical immunology.
[116] E. Gelfand,et al. Role of IgE in the development of allergic airway inflammation and airway hyperresponsiveness – a murine model , 1999, Allergy.
[117] H. van Loveren,et al. Long-term topical exposure to toluene diisocyanate in mice leads to antibody production and in vivo airway hyperresponsiveness three hours after intranasal challenge. , 1999, American journal of respiratory and critical care medicine.
[118] C. Cohen,et al. Selective Induction of Interleukin-12 in Reconstructed Human Epidermis by Chemical Allergens , 1999, Alternatives to laboratory animals : ATLA.
[119] H. Meurs,et al. Role of L‐arginine in the deficiency of nitric oxide and airway hyperreactivity after the allergen‐induced early asthmatic reaction in guinea‐pigs , 1999, British journal of pharmacology.
[120] I. Kimber,et al. Chemical respiratory allergy, IgE and the relevance of predictive test methods: a commentary , 1998, Human & experimental toxicology.
[121] L. Grammer,et al. Utility of antibody in identifying individuals who have or will develop anhydride-induced respiratory disease. , 1998, Chest.
[122] N. Bloksma,et al. Airway morphology and function of rats following dermal sensitization and respiratory challenge with low molecular weight chemicals. , 1998, Toxicology and applied pharmacology.
[123] A. Primavera,et al. Selective induction of cell-associated interleukin-1alpha in murine keratinocytes by chemical allergens. , 1998, Toxicology.
[124] D. Kemeny,et al. Cytokine Production by CD4+ and CD8+ T Cells in Mice following Primary Exposure to Chemical Allergens: Evidence for Functional Differentiation of T Lymphocytes in vivo , 1998, International Archives of Allergy and Immunology.
[125] Cullinan. Occupational asthma, IgE and IgG , 1998, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.
[126] R D Tee,et al. Specific IgE to isocyanates: a useful diagnostic role in occupational asthma. , 1998, The Journal of allergy and clinical immunology.
[127] J. Youn,et al. Heterogeneity of IgE response to TDI-HSA conjugates by ELISA in toluene diisocyanate (TDI) -induced occupational asthma (OA) patients. , 1998, Journal of Korean medical science.
[128] D. Basketter,et al. Estimation of relative skin sensitizing potency using the local lymph node assay: a comparison of formaldehyde with glutaraldehyde. , 1998, American journal of contact dermatitis : official journal of the American Contact Dermatitis Society.
[129] I. Kimber,et al. Inducible interleukin 4 (IL-4) production and mRNA expression following exposure of mice to chemical allergens. , 1998, Toxicology letters.
[130] J. Lötvall,et al. Relationship between IgG1 levels and airway responses in guinea pigs actively and passively sensitized to hexahydrophthalic anhydride , 1998, Allergy.
[131] J. Pauluhn,et al. Assessment of respiratory hypersensitivity in guinea pigs sensitized to toluene diisocyanate: improvements on analysis of respiratory response. , 1997, Fundamental and applied toxicology : official journal of the Society of Toxicology.
[132] H. Rosenkranz,et al. Structure-activity model of chemicals that cause human respiratory sensitization. , 1997, Regulatory toxicology and pharmacology : RTP.
[133] S. Papiris,et al. Expression of interleukin (IL)‐4 and IL‐5 proteins in asthma induced by toluene diisocyanate (TDI) , 1997, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.
[134] N. Bloksma,et al. Local lymph node activation and IgE responses in brown Norway and Wistar rats after dermal application of sensitizing and non-sensitizing chemicals. , 1997, Toxicology.
[135] I. Kimber,et al. Toxicology of Chemical Respiratory Hypersensitivity , 1997 .
[136] I. Bernstein,et al. Occupational Respiratory Allergy , 1997 .
[137] D. Basketter,et al. Classification of Chemical Allergens According to Cytokine Secretion Profiles of Murine Lymph Node Cells , 1997, Journal of applied toxicology : JAT.
[138] I. Bernstein,et al. Identification of Respiratory Allergens , 1996 .
[139] I. Bernstein,et al. Workshop overview. Identification of respiratory allergens. , 1996, Fundamental and Applied Toxicology.
[140] Emanuela Corsini,et al. Alternative Methods for Skin Sensitisation Testing , 1996 .
[141] H. Rosenkranz,et al. Structure-activity relationships and computer-assisted analysis of respiratory sensitization potential. , 1996, Toxicology letters.
[142] A. Woodcock,et al. Exposure to house dust mite allergens and the clinical activity of asthma. , 1996, The Journal of allergy and clinical immunology.
[143] D. Basketter,et al. Characterization of chemical allergens as a function of divergent cytokine secretion profiles induced in mice. , 1996, Toxicology and applied pharmacology.
[144] H. Nordman,et al. Occupational asthma: measures of frequency from four countries. , 1996, Thorax.
[145] D. Basketter,et al. The Mouse IgE Test for the Identification of Potential Chemical Respiratory Allergens: Considerations of Stability and Controls , 1996, Journal of applied toxicology : JAT.
[146] T. Estlander,et al. Occupational laryngitis with immediate allergic or immediate type specific chemical hypersensitivity. , 1996, Clinical otolaryngology and allied sciences.
[147] N. Balato,et al. Acne and allergic contact dermatitis , 1996, Contact dermatitis.
[148] J. Lötvall,et al. Airway responses following intradermal sensitization to different types of allergens: ovalbumin, trimellitic anhydride and Dermatophagoides farinae. , 1995, International archives of allergy and immunology.
[149] P. Cullinan,et al. Consequences of occupational asthma , 1995, BMJ.
[150] O'Hollaren Mt. Dyspnea and the larynx. , 1995 .
[151] D. Potter,et al. Total IgE antibody production in BALB/c mice after dermal exposure to chemicals. , 1995, Fundamental and applied toxicology : official journal of the Society of Toxicology.
[152] D. Tollerud,et al. A murine model for assessing the respiratory hypersensitivity potential of chemical allergens. , 1995, Toxicology letters.
[153] X. Baur,et al. Hypersensitivity pneumonitis (extrinsic allergic alveolitis) induced by isocyanates. , 1995, The Journal of allergy and clinical immunology.
[154] P. Botham,et al. A two-centre study for the evaluation and validation of an animal model for the assessment of the potential of small molecular weight chemicals to cause respiratory allergy. , 1995, Toxicology.
[155] P Maestrelli,et al. CD8 T-cell clones producing interleukin-5 and interferon-gamma in bronchial mucosa of patients with asthma induced by toluene diisocyanate. , 1994, Scandinavian journal of work, environment & health.
[156] D A Basketter,et al. An expert system rulebase for identifying contact allergens. , 1994, Toxicology in vitro : an international journal published in association with BIBRA.
[157] I Kimber,et al. The local lymph node assay: developments and applications. , 1994, Toxicology.
[158] J. Pauluhn,et al. Assessment of respiratory hypersensitivity in guinea-pigs sensitized to diphenylmethane-4,4'-diisocyanate (MDI) and challenged with MDI, acetylcholine or MDI-albumin conjugate. , 1994, Toxicology.
[159] D. Basketter,et al. Inducible interleukin-4-secreting cells provoked in mice during chemical sensitization. , 1994, Immunology.
[160] P. Botham,et al. Induction of respiratory hypersensitivity to diphenylmethane-4,4'-diisocyanate (MDI) in guinea pigs. Influence of route of exposure. , 1994, Toxicology.
[161] R. Elton,et al. Occupational asthma and the chemical properties of low molecular weight organic substances. , 1994, Occupational medicine.
[162] J. P. Hayes,et al. Airway allergy to trimellitic anhydride in guinea pigs: different time courses of IgG1 titer and airway responses to allergen challenge. , 1993, The Journal of allergy and clinical immunology.
[163] Moira Chan-Yeung,et al. Asthma in the Workplace , 1993 .
[164] J. Lesage,et al. Prepolymers of hexamethylene diisocyanate as a cause of occupational asthma. , 1993, The Journal of allergy and clinical immunology.
[165] B. Nemery,et al. Exposure to methylene diphenyl diisocyanate in coal mines , 1993, The Lancet.
[166] A. Kuroiwa,et al. Guinea pig model of immunologic asthma induced by inhalation of trimellitic anhydride. , 1992, The American review of respiratory disease.
[167] D. Basketter,et al. Variable effects of chemical allergens on serum ige concentration in mice. Preliminary evaluation of a novel approach to the identification of respiratory sensitizers , 1992, Journal of applied toxicology : JAT.
[168] D. Basketter,et al. Differential ability of occupational chemical contact and respiratory allergens to cause immediate and delayed dermal hypersensitivity reactions in mice. , 1992, International archives of allergy and immunology.
[169] P. Jl,et al. Experimental models of hypersensitivity pneumonitis. , 1992 .
[170] P Maestrelli,et al. Activated T-lymphocytes and eosinophils in the bronchial mucosa in isocyanate-induced asthma. , 1992, The Journal of allergy and clinical immunology.
[171] I Kimber,et al. The murine local lymph node assay: a commentary on collaborative studies and new directions. , 1992, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.
[172] A. Robertson,et al. Structure activity hypotheses in occupational asthma caused by low molecular weight substances. , 1991, The Annals of occupational hygiene.
[173] I. Kimber,et al. Differential stimulation of immune function by respiratory and contact chemical allergens. , 1991, Immunology.
[174] J. Malo,et al. Specific serum antibodies against isocyanates: association with occupational asthma. , 1989, The Journal of allergy and clinical immunology.
[175] H. van Loveren,et al. Regulation of delayed-type hypersensitivity-like responses in the mouse lung, determined with histological procedures: serotonin, T-cell suppressor-inducer factor and high antigen dose tolerance regulate the magnitude of T-cell dependent inflammatory reactions. , 1989, Immunology.
[176] P. Botham,et al. The induction of respiratory allergy in guinea-pigs following intradermal injection of trimellitic anhydride: a comparison with the response to 2,4-dinitrochlorobenzene. , 1989, Toxicology letters.
[177] P. Botham,et al. Sensitisation of guinea pigs by inhalation exposure to low molecular weight chemicals. , 1988, Toxicology letters.
[178] M. Karol. Concentration-dependent immunologic response to toluene diisocyanate (TDI) following inhalation exposure. , 1983, Toxicology and applied pharmacology.
[179] Y. Alarie,et al. Immunologic sensitization and pulmonary hypersensitivity by repeated inhalation of aromatic isocyanates. , 1980, Toxicology and applied pharmacology.
[180] W. Mitchell Sams,et al. Allergic Contact Dermatitis in the Guinea Pig , 1971 .
[181] Darrell R Boverhof,et al. Respiratory sensitization and allergy: current research approaches and needs. , 2008, Toxicology and applied pharmacology.
[182] J. Arts,et al. Animal models to test respiratory allergy of low molecular weight chemicals: a guidance. , 2007, Methods.
[183] Erwin L Roggen,et al. An in silico method using an epitope motif database for predicting the location of antigenic determinants on proteins in a structural context , 2006, Journal of molecular recognition : JMR.
[184] Romualdo Benigni,et al. Structure-activity models of chemical carcinogens: state of the art, and new directions. , 2006, Annali dell'Istituto superiore di sanita.
[185] S. Spector,et al. Asthma in the Workplace, 3rd ed (Bernstein IL, Chan-Yeung M, Malo J-L, Bernstein DI, editors) , 2006 .
[186] L. Fabbri,et al. Occupational asthma. , 2005, American journal of respiratory and critical care medicine.
[187] I. Kimber,et al. Induced changes in total serum IgE concentration in the Brown Norway rat: potential for identification of chemical respiratory allergens , 2002, Journal of applied toxicology : JAT.
[188] M. Barratt,et al. Studies of the chemical selectivity of hapten, reactivity, and skin sensitization potency. 1. Synthesis and studies on the reactivity toward model nucleophiles of the (13)C-labeled skin sensitizers hex-1-ene- and hexane-1,3-sultones. , 2001, Chemical research in toxicology.
[189] N. Bloksma,et al. Respiratory irritation by trimellitic anhydride in Brown Norway and Wistar rats. , 2001, Inhalation toxicology.
[190] M. Barratt,et al. Studies of the chemical selectivity of hapten, reactivity, and skin sensitization potency. 2. nmr studies of the covalent binding of the (13)c-labeled skin sensitizers 2-[13C]- and 3-[13C]hex-1-ene- and 3-[13C]hexane-1,3-sultones to human serum albumin. , 2001, Chemical research in toxicology.
[191] A. Enk,et al. Contact sensitizers specifically increase MHC class II expression on murine immature dendritic cells. , 2000, In vitro & molecular toxicology.
[192] M. Karol,et al. The importance of the diluent for airway transport of toluene diisocyanate following intranasal dosing of mice. , 1999, Inhalation toxicology.
[193] T. Landry,et al. Respiratory hypersensitivity to diphenylmethane-4,4'-diisocyanate in guinea pigs: comparison with trimellitic anhydride. , 1999, Inhalation toxicology.
[194] P. Germann,et al. INCIDENCE AND SEVERITY OF GRANULOMATOUS PNEUMONIA IN BROWN NORWAY (BN) RATS : BREEDER RELATED VARIATIONS , 1998 .
[195] D. Roberts,et al. Structure—Activity Relationships for Contact Hypersensitivity , 1998 .
[196] D. Basketter,et al. THE MOUSE IgE TEST: INTERLABORATORY EVALUATION AND COMPARISON OF BALB/c AND C57BL/6 STRAIN MICE , 1998 .
[197] I. Kimber,et al. Cell and molecular biology of chemical allergy , 1997, Clinical reviews in allergy & immunology.
[198] M. O'hollaren. Dyspnea and the larynx. , 1995, Annals of Allergy, Asthma & Immunology.
[199] D. Basketter,et al. Identification of Chemical Respiratory Allergens: Dose-Response Relationships in the Mouse IgE Test , 1995 .
[200] A. Zwart,et al. Wave propagation: a new parameter in the description of mechanical airway impedance , 1994 .
[201] J. L. Pérez Arellano,et al. Experimental models of hypersensitivity pneumonitis. , 1992, Journal of investigational allergology & clinical immunology.
[202] D A Basketter,et al. Skin sensitization--a critical review of predictive test methods in animals and man. , 1991, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.
[203] A. Kuroiwa,et al. Experimental lung injury induced by trimellitic anhydride inhalation on guinea pigs. , 1991, International Archives of Allergy and Applied Immunology.
[204] L. Belin,et al. Immunologic specificity of isocyanate-induced IgE antibodies in serum from 10 sensitized workers. , 1989, The Journal of allergy and clinical immunology.
[205] H. Maibach,et al. Contact allergy predictive tests in guinea pigs. , 1985, Current problems in dermatology.
[206] A. Kligman,et al. Allergic contact dermatitis in the guinea pig : identifications of contact allergens , 1970 .
[207] C. F. H. Allen,et al. Acid anhydrides. , 1946, Organic syntheses; an annual publication of satisfactory methods for the preparation of organic chemicals.