Prediction of drug-induced cardiotoxicity using human embryonic stem cell-derived cardiomyocytes.
暂无分享,去创建一个
Robert Passier | Christine L Mummery | Anja van de Stolpe | R. Passier | C. Mummery | A. van de Stolpe | L. Tertoolen | S. Braam | T. Meyer | Stefan R Braam | Leon Tertoolen | Thomas Meyer
[1] E. Lindström,et al. QTc interval prolongation and antipsychotic drug treatments: focus on sertindole. , 2005, The international journal of neuropsychopharmacology.
[2] CARDIOTOXICITY OF INTRAVENOUS, DOMPERIDONE , 1985, The Lancet.
[3] Ido Perlman,et al. Mechanism of spontaneous excitability in human embryonic stem cell derived cardiomyocytes , 2004, The Journal of physiology.
[4] L. Gepstein,et al. Identification and selection of cardiomyocytes during human embryonic stem cell differentiation , 2007, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
[5] Christine L. Mummery,et al. Embryonic Stem (es) Cells from Mice and Primates Can Differentiate into Any Cell Type in the Adult Body Stem Cells in Fetal and Adult Hearts Stem-cell-based Therapy and Lessons from the Heart Insight Review , 2022 .
[6] R. Passier,et al. Insulin Redirects Differentiation from Cardiogenic Mesoderm and Endoderm to Neuroectoderm in Differentiating Human Embryonic Stem Cells , 2008, Stem cells.
[7] Hendrik Bonnemeier,et al. The electrocardiogram of human embryonic stem cell-derived cardiomyocytes. , 2005, Journal of electrocardiology.
[8] C. Denning,et al. Cardiomyocytes from human embryonic stem cells as predictors of cardiotoxicity , 2008 .
[9] H. Duff,et al. Class I antiarrhythmic drug receptor: biochemical evidence for state-dependent interaction with quinidine and lidocaine. , 1989, Molecular pharmacology.
[10] P. Doevendans,et al. Patterning the heart, a template for human cardiomyocyte development , 2006, Developmental dynamics : an official publication of the American Association of Anatomists.
[11] A. Brown,et al. HERG, a primary human ventricular target of the nonsedating antihistamine terfenadine. , 1996, Circulation.
[12] K. Olejniczak,et al. ICH Topic: The draft ICH S7B step 2: Note for guidance on safety pharmacology studies for human pharmaceuticals , 2002, Fundamental & clinical pharmacology.
[13] Chris Denning,et al. Transgenic enrichment of cardiomyocytes from human embryonic stem cells. , 2007, Molecular therapy : the journal of the American Society of Gene Therapy.
[14] Gary A Gintant,et al. The Utility of hERG and Repolarization Assays in Evaluating Delayed Cardiac Repolarization: Influence of Multi-Channel Block , 2004, Journal of cardiovascular pharmacology.
[15] E. Stanley,et al. The hESC line Envy expresses high levels of GFP in all differentiated progeny , 2005, Nature Methods.
[16] L. Fauchier,et al. Effect of verapamil on QT interval dynamicity. , 1999, The American journal of cardiology.
[17] D. Roden,et al. Frequency-dependent interactions of mexiletine and quinidine on depolarization and repolarization in canine Purkinje fibers. , 1987, The Journal of pharmacology and experimental therapeutics.
[18] R. Passier,et al. Differentiation of human embryonic stem cells to cardiomyocytes by coculture with endoderm in serum-free medium. , 2007, Current protocols in stem cell biology.
[19] W. Crumb,et al. Quinidine interactions with human atrial potassium channels: developmental aspects. , 1998, Circulation research.
[20] S. Liu,et al. Inhibition of L-type Ca2+ channel current in rat ventricular myocytes by terfenadine. , 1997, Circulation research.
[21] Robert Passier,et al. Increased Cardiomyocyte Differentiation from Human Embryonic Stem Cells in Serum‐Free Cultures , 2005, Stem cells.
[22] Robert Passier,et al. Cardiomyocyte differentiation from embryonic and adult stem cells. , 2005, Current opinion in biotechnology.
[23] R Lazzara,et al. Multiple mechanisms in the long-QT syndrome. Current knowledge, gaps, and future directions. The SADS Foundation Task Force on LQTS. , 1996, Circulation.
[24] Icilio Cavero,et al. ICH S7B draft guideline on the non-clinical strategy for testing delayed cardiac repolarisation risk of drugs: a critical analysis , 2005, Expert opinion on drug safety.
[25] Rene Spijker,et al. Differentiation of Human Embryonic Stem Cells to Cardiomyocytes: Role of Coculture With Visceral Endoderm-Like Cells , 2003, Circulation.
[26] RenéCardinal,et al. Domperidone Should Not Be Considered a No-Risk Alternative to Cisapride in the Treatment of Gastrointestinal Motility Disorders , 2000 .
[27] L. Hondeghem,et al. Quinidine blocks cardiac sodium channels during opening and slow inactivation in guinea‐pig papillary muscle , 1988, British journal of pharmacology.
[28] L. V. Van Laake,et al. Human embryonic stem cells: genetic manipulation on the way to cardiac cell therapies. , 2005, Reproductive toxicology.
[29] Benjamin A Lipsky,et al. Safety profile of sparfloxacin, a new fluoroquinolone antibiotic. , 1999, Clinical therapeutics.
[30] A. Camm,et al. Relationships between preclinical cardiac electrophysiology, clinical QT interval prolongation and torsade de pointes for a broad range of drugs: evidence for a provisional safety margin in drug development. , 2003, Cardiovascular research.
[31] B. Darpö,et al. Spectrum of drugs prolonging QT interval and the incidence of torsades de pointes , 2001 .
[32] Stanley Nattel,et al. Dofetilide block involves interactions with open and inactivated states of HERG channels , 2002, Pflügers Archiv - European Journal of Physiology.
[33] A. Hoes,et al. Anti-HERG activity and the risk of drug-induced arrhythmias and sudden death. , 2005, European heart journal.
[34] Arthur J Moss,et al. Long QT syndrome: from channels to cardiac arrhythmias. , 2005, The Journal of clinical investigation.
[35] Lior Gepstein,et al. In vitro electrophysiological drug testing using human embryonic stem cell derived cardiomyocytes. , 2009, Stem cells and development.
[36] Shingo Suzuki,et al. Comparison of kinetic properties of quinidine and dofetilide block of HERG channels. , 2004, European journal of pharmacology.
[37] A. Colman,et al. Highly enriched cardiomyocytes from human embryonic stem cells. , 2008, Cytotherapy.
[38] S. Bryant,et al. Comparison of guinea-pig ventricular myocytes and dog Purkinje fibres for in vitro assessment of drug-induced delayed repolarization. , 2007, Journal of pharmacological and toxicological methods.
[39] P. C. Viswanathan,et al. Genetics of acquired long QT syndrome. , 2005, The Journal of clinical investigation.
[40] C. Mummery,et al. Enhanced cardiomyogenesis of human embryonic stem cells by a small molecular inhibitor of p38 MAPK. , 2008, Differentiation; research in biological diversity.