A review on scope of immuno-modulatory drugs in Ayurveda for prevention and treatment of Covid-19

The Coronavirus disease 2019 (COVID-19) is caused by severe acute respiratory syndrome Coronavirus-2 (SARS CoV-2) infection attacking mainly on the immune system of a body It is a potentially fatal disease that is of public health and economy concern globally In December 2019, COVID-19 outbreak occurred in Wuhan city, Hubei Province, China furthermore spread worldwide Research is underway in many countries to develop effective vaccines and drugs for the COVID-19 In Ayurveda, Acharya Charaka explained the concept of an epidemic condition in Janapadodhwansa Adhayay and combating of these diseases is to be done by Panchakarma (five procedures of purification), Rasayana Chikitsa (immune-modulators therapy) and Sadvritta (good conduct) Rasayan dravyas (immunomodulator drugs) of Ayurveda can be used for health promotion, immune-modulation, prevention and reduce disease burden from COVID-19 Drugs such as Ashwagandha (Withania somnifera (L ) Dunal), Guduchi (Tinospora cordifolia (Willd ) Miers), Amalaki (Phyllanthus emblica L ), Mulethi (Glycyrrhiza glabra L ), Shatavari (Asparagus racemosus Wild ), Chireta (Andrographis paniculata (Burm f ) Nees), Tulsi (Ocimum sanctum L ) Punarnava (Boerhaavia diffusa L ) and Pippali (Piper longum L ) For symptom management of COVID-19 like illness Agastya Haritaki, Anutaila, AYUSH-64 can be used Scientific research on these drugs may reveal the new approach for the prevention and management of COVID-19 The main aim of this article is to review research which has already conducted and currently being carried out on the herbal plant for their immunomodulation property which have a possible application in the prevention and treatment of COVID-19