Autocrine erythropoietin signaling inhibits hypoxia-induced apoptosis in human breast carcinoma cells.

[1]  Xiaowei Xu,et al.  Prognostic significance of erythropoietin expression in human endometrial carcinoma , 2004, Cancer.

[2]  B. Teicher.  Hypoxia and drug resistance , 1994, Cancer and Metastasis Reviews.

[3]  H. Shimada,et al.  Pediatric Tumor Cells Express Erythropoietin and a Functional Erythropoietin Receptor that Promotes Angiogenesis and Tumor Cell Survival , 2003, Laboratory Investigation.

[4]  Ahmed Mohyeldin,et al.  Hypoxia-inducible erythropoietin signaling in squamous dysplasia and squamous cell carcinoma of the uterine cervix and its potential role in cervical carcinogenesis and tumor progression. , 2003, The American journal of pathology.

[5]  C. Ricordi,et al.  Human, nonhuman primate, and rat pancreatic islets express erythropoietin receptors1 , 2003, Transplantation.

[6]  T. Rebbeck,et al.  Immunohistochemical expression of erythropoietin and erythropoietin receptor in breast carcinoma , 2002, Cancer.

[7]  C. Koch,et al.  Measurement of absolute oxygen levels in cells and tissues using oxygen sensors and 2-nitroimidazole EF5. , 2002, Methods in enzymology.

[8]  C. Dive,et al.  Apoptosis and cancer chemotherapy. , 2001, Trends in cell biology.

[9]  P Vaupel,et al.  Oxygen status of malignant tumors: pathogenesis of hypoxia and significance for tumor therapy. , 2001, Seminars in oncology.

[10]  W. Brück,et al.  Erythropoietin and erythropoietin receptor in human ischemic/hypoxic brain , 2001, Acta Neuropathologica.

[11]  J. Dame,et al.  Origin and Fate of Erythropoietin in Human Milk , 2000, Pediatric Research.

[12]  Y. Asano,et al.  Erythropoietin regulates vascular smooth muscle cell apoptosis by a phosphatidylinositol 3 kinase-dependent pathway. , 2000, Kidney international.

[13]  H. Bartelink,et al.  Radiation-induced apoptosis , 2000, Cell and Tissue Research.

[14]  D. Hanahan,et al.  The Hallmarks of Cancer , 2000, Cell.

[15]  S. Masuda,et al.  Erythropoietin: Multiple Physiological Functions and Regulation of Biosynthesis , 2000, Bioscience, biotechnology, and biochemistry.

[16]  G. Semenza.  Expression of hypoxia-inducible factor 1: mechanisms and consequences. , 2000, Biochemical pharmacology.

[17]  R. Gregory,et al.  Signal transduction in the erythropoietin receptor system. , 1999, Experimental cell research.

[18]  K. Wiman,et al.  p53-induced apoptosis as a safeguard against cancer. , 1999, Biochemical and biophysical research communications.

[19]  S. Klinken,et al.  The erythropoietin receptor. , 1999, The international journal of biochemistry & cell biology.

[20]  F. Prósper,et al.  Erythropoietin Can Induce the Expression of Bcl-xLthrough Stat5 in Erythropoietin-dependent Progenitor Cell Lines* , 1999, The Journal of Biological Chemistry.

[21]  S. Masuda,et al.  Erythropoietic, neurotrophic, and angiogenic functions of erythropoietin and regulation of erythropoietin production. , 1999, International journal of hematology.

[22]  S. Juul,et al.  Erythropoietin in the neonate. , 1999, Current problems in pediatrics.

[23]  B. Joseph,et al.  Tumor radiosensitivity and apoptosis. , 1999, Experimental cell research.

[24]  K. Conrad,et al.  Expression of the erythropoietin receptor by trophoblast cellsin the human placenta. , 1999, Biology of reproduction.

[25]  M. Rothstein,et al.  Effect of recombinant human erythropoietin on endothelial cell apoptosis. , 1999, Kidney international.

[26]  M. Goldberg,et al.  Regulation of the erythropoietin gene , 1993, Blood.

[27]  P. Mayeux,et al.  The molecular biology of erythropoietin. , 1999, Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.

[28]  J. Weinberg,et al.  Mechanisms of cell death in hypoxia/reoxygenation injury , 1998, Oncogene.

[29]  K. Claffey,et al.  Hypoxia‐mediated regulation of gene expression in mammalian cells , 1998, International journal of experimental pathology.

[30]  X. Leverve,et al.  Cellular physiology and molecular events in hypoxia-induced apoptosis. , 1998, Anticancer research.

[31]  T. Fojo,et al.  p53 Inhibits Hypoxia-inducible Factor-stimulated Transcription* , 1998, The Journal of Biological Chemistry.

[32]  D. Fisher,et al.  Regulation of Proliferation-Survival Decisions during Tumor Cell Hypoxia , 1998, Molecular and Cellular Biology.

[33]  Yan Li,et al.  Erythropoietin and Erythropoietin Receptor in the Developing Human Central Nervous System , 1998, Pediatric Research.

[34]  J. Prchal,et al.  Human hematopoietic progenitors express erythropoietin. , 1998, Blood.

[35]  Chris E. Cooper,et al.  Oxygen Transport to Tissue XVIII , 2012, Advances in Experimental Medicine and Biology.

[36]  E. Wintour,et al.  Developmental regulation of erythropoietin and erythropoiesis. , 1997, American journal of physiology. Regulatory, integrative and comparative physiology.

[37]  T. Stokke,et al.  Hypoxia-induced apoptosis in human cells with normal p53 status and function, without any alteration in the nuclear protein level. , 1997, Experimental cell research.

[38]  P. Glazer,et al.  Genetic instability induced by the tumor microenvironment. , 1996, Cancer research.

[39]  P Vaupel,et al.  Association between tumor hypoxia and malignant progression in advanced cancer of the uterine cervix. , 1996, Cancer research.

[40]  M. Dewhirst,et al.  Tumor oxygenation predicts for the likelihood of distant metastases in human soft tissue sarcoma. , 1996, Cancer research.

[41]  C. Koch,et al.  2-Nitroimidazole (EF5) binding predicts radiation resistance in individual 9L s.c. tumors. , 1996, Cancer research.

[42]  David E. Housman,et al.  Hypoxia-mediated selection of cells with diminished apoptotic potential in solid tumours , 1996, Nature.

[43]  D Grillot,et al.  Erythropoietin can promote erythroid progenitor survival by repressing apoptosis through Bcl-XL and Bcl-2. , 1996, Blood.

[44]  P. Mayeux,et al.  The signal transduction pathway of erythropoietin involves three forms of mitogen-activated protein (MAP) kinase in UT7 erythroleukemia cells. , 1995, European journal of biochemistry.

[45]  E. Rofstad,et al.  Correlation of high lactate levels in human cervical cancer with incidence of metastasis. , 1995, Cancer research.

[46]  B. Groner,et al.  Interleukin-3, Erythropoietin, and Prolactin Activate a STAT5-like Factor in Lymphoid Cells (*) , 1995, The Journal of Biological Chemistry.

[47]  M. Raff,et al.  Programmed cell death and Bcl-2 protection in very low oxygen , 1995, Nature.

[48]  Y. Tsujimoto,et al.  Prevention of hypoxia-induced cell death by Bcl-2 and Bcl-xL , 1995, Nature.

[49]  R. Muschel,et al.  Induction of apoptosis at different oxygen tensions: evidence that oxygen radicals do not mediate apoptotic signaling. , 1995, Cancer research.

[50]  J. Pelletier,et al.  Clonal expansion and attenuated apoptosis in Wilms' tumors are associated with p53 gene mutations. , 1995, Cancer research.

[51]  N. Aoki,et al.  Activation of the mitogen-activated protein kinase pathway by the erythropoietin receptor. , 1994, The Journal of biological chemistry.

[52]  S. Lowe,et al.  p53-Dependent apoptosis suppresses tumor growth and progression in vivo , 1994, Cell.

[53]  A. Anagnostou,et al.  Erythropoietin receptor mRNA expression in human endothelial cells. , 1994, Proceedings of the National Academy of Sciences of the United States of America.

[54]  W. Jelkmann,et al.  Biology of erythropoietin. , 1994, The Clinical investigator.

[55]  B. Ebert,et al.  Regulation of the erythropoietin gene. , 1999, Blood.

[56]  D. Bredesen,et al.  bcl-2 inhibits death of central neural cells induced by multiple agents. , 1993, Proceedings of the National Academy of Sciences of the United States of America.

[57]  P Vaupel,et al.  Oxygenation of human tumors: evaluation of tissue oxygen distribution in breast cancers by computerized O2 tension measurements. , 1991, Cancer research.

[58]  P. Okunieff,et al.  Blood flow, oxygen and nutrient supply, and metabolic microenvironment of human tumors: a review. , 1989, Cancer research.

[59]  R. Hill,et al.  Hypoxia induces DNA overreplication and enhances metastatic potential of murine tumor cells. , 1988, Proceedings of the National Academy of Sciences of the United States of America.

[60]  R. Gatenby,et al.  Oxygen distribution in squamous cell carcinoma metastases and its relationship to outcome of radiation therapy. , 1988, International journal of radiation oncology, biology, physics.

[61]  E. Pettersen,et al.  Regulation of protein metabolism of human cells during and after acute hypoxia. , 1986, Cancer research.

[62]  A J Dembo,et al.  Definitive evidence for hypoxic cells influencing cure in cancer therapy. , 1978, The British journal of cancer. Supplement.