Metabolic zonation of liver parenchyma: significance for the regulation of glycogen metabolism, gluconeogenesis, and glycolysis.

[1]  K. Jungermann,et al.  A portal‐arterial glucose concentration gradient as a signal for an insulin‐dependent net glucose uptake in perfused rat liver , 1986, FEBS letters.

[2]  K. Jungermann,et al.  Control of glucose balance in the perfused rat liver by the parasympathetic innervation. , 1986, Biological chemistry Hoppe-Seyler.

[3]  K. Jungermann Zonal Signal Heterogeneity and Induction of Hepatocyte Heterogeneity , 1986 .

[4]  D. Sasse Liver Structure and Innervation , 1986 .

[5]  N. Katz,et al.  The pubertal sex-specific development of zonation of fatty acid synthase in rat liver. , 1986, Acta histochemica. Supplementband.

[6]  K. Jungermann,et al.  Functional heterogeneity of periportal and perivenous hepatocytes. , 1986, Enzyme.

[7]  K. Jungermann,et al.  Long-term effects of physiological oxygen concentrations on glycolysis and gluconeogenesis in hepatocyte cultures. , 1985, European journal of biochemistry.

[8]  K. Jungermann,et al.  Glucostat capacity and metabolic zonation in rat liver after portocaval anastomosis. , 1985, Biological chemistry Hoppe-Seyler.

[9]  K. Jungermann,et al.  Control of oxygen uptake, microcirculation and glucose release by circulating noradrenaline in perfused rat liver. , 1985, Biological chemistry Hoppe-Seyler.

[10]  A. Cherrington,et al.  What the papers say: Role of hepatic glycolysis and gluconeogenesis in glycogen synthesis , 1985 .

[11]  H. Miethke,et al.  糖尿病ラット肝臓の代謝の帯状分布 ホスホエノールピルビン酸カルボキシキナーゼ,ピルビン酸キナーゼ,グルコース‐6‐ホスファターゼ,こはく酸デヒドロゲナーゼの帯状分布 , 1985 .

[12]  K. Jungermann,et al.  Metabolic zonation in liver of diabetic rats. Zonal distribution of phosphoenolpyruvate carboxykinase, pyruvate kinase, glucose-6-phosphatase and succinate dehydrogenase. , 1985, Biological chemistry Hoppe-Seyler.

[13]  K. Jungermann,et al.  Alteration with dietary state of the activity and zonal distribution of adenylate cyclase stimulated by glucagon, fluoride and forskolin in microdissected rat liver tissue. , 1984, European journal of biochemistry.

[14]  J. McGarry,et al.  The glucose paradox. Is glucose a substrate for liver metabolism? , 1984, The Journal of clinical investigation.

[15]  R. Thurman,et al.  Gluconeogenesis predominates in periportal regions of the liver lobule. , 1984, European journal of biochemistry.

[16]  C. Newgard,et al.  Efficient hepatic glycogen synthesis in refeeding rats requires continued carbon flow through the gluconeogenic pathway. , 1984, The Journal of biological chemistry.

[17]  L. Saccá,et al.  Differential roles of splanchnic and peripheral tissues in the pathogenesis of impaired glucose tolerance. , 1984, The Journal of clinical investigation.

[18]  K. Jungermann,et al.  Regulation of peripheral insulin/glucagon levels by rat liver. , 1984, European journal of biochemistry.

[19]  R. Thurman,et al.  Predominance of glycolysis in pericentral regions of the liver lobule. , 1984, European journal of biochemistry.

[20]  K. Jungermann,et al.  Regulation of oxygen consumption and microcirculation by α‐sympathetic nerves in isolated perfused rat liver , 1984, FEBS letters.

[21]  W. Lautt,et al.  Afferent and efferent neural roles in liver function , 1983, Progress in Neurobiology.

[22]  K. Jungermann,et al.  The glucagon-insulin antagonism and glucagon-dexamethasone synergism in the induction of phosphoenolpyruvate carboxykinase in cultured rat hepatocytes. , 1983, Hoppe-Seyler's Zeitschrift fur physiologische Chemie.

[23]  J. Radziuk,et al.  The Effects of Ingested and Intravenous Glucose on Forearm Uptake of Glucose and Glucogenic Substrate in Normal Man , 1983, Diabetes.

[24]  K. Jungermann,et al.  Short-term modulation of glycogen metabolism, glycolysis and gluconeogenesis by physiological oxygen concentrations in hepatocyte cultures. , 1983, European journal of biochemistry.

[25]  W. Fischer,et al.  Distribution of enzymes of fatty acid and ketone body metabolism in periportal and perivenous rat-liver tissue. , 1983, European journal of biochemistry.

[26]  K. Jungermann,et al.  Short-term regulation of glycolysis by insulin and dexamethasone in cultured rat hepatocytes. , 1983, European journal of biochemistry.

[27]  M. Sugden,et al.  Direction of carbon flux in starvation and after refeeding: in vitro and in vivo effects of 3-mercaptopicolinate. , 1983, Biochemistry international.

[28]  C. Newgard,et al.  Studies on the mechanism by which exogenous glucose is converted into liver glycogen in the rat. A direct or an indirect pathway? , 1983, The Journal of biological chemistry.

[29]  R. DeFronzo,et al.  Splanchnic and Peripheral Disposal of Oral Glucose in Man , 1983, Diabetes.

[30]  R. Thurman,et al.  Measuring rates of O2 uptake in periportal and pericentral regions of liver lobule: stop-flow experiments with perfused liver. , 1983, The American journal of physiology.

[31]  K. Jungermann,et al.  Perinatal development of the distributions of phosphoenolpyruvate carboxykinase and succinate dehydrogenase in rat liver parenchyma. , 1983, European journal of cell biology.

[32]  W. Fischer,et al.  Heterogeneous distribution of ATP citrate lyase in rat-liver parenchyma. Microradiochemical determination in microdissected periportal and perivenous liver tissue. , 1983, European journal of biochemistry.

[33]  K. Jungermann,et al.  Distribution of pyruvate kinase type L and M2 in microdissected periportal and perivenous rat liver tissue with different dietary states. , 1983, Hoppe-Seyler's Zeitschrift fur physiologische Chemie.

[34]  H G Hers,et al.  Gluconeogenesis and related aspects of glycolysis. , 1983, Annual review of biochemistry.

[35]  T. Shimazu,et al.  Reciprocal innervation of the liver: its significance in metabolic control. , 1983, Advances in metabolic disorders.

[36]  K. Jungermann,et al.  Functional Hepatocellular Heterogeneity , 2007, Hepatology.

[37]  K. Jungermann,et al.  Direct control of glycogen metabolism in the perfused rat liver by the sympathetic innervation. , 2005, European journal of biochemistry.

[38]  K. Jungermann,et al.  Induction in primary culture of 'gluconeogenic' and 'glycolytic' hepatocytes resembling periportal and perivenous cells. , 2005, European journal of biochemistry.

[39]  K. Jungermann,et al.  Activation of glycogenolysis and norepinephrine overflow in the perfused rat liver during repetitive perivascular nerve stimulation , 1982, FEBS letters.

[40]  P. Tippett,et al.  Specific inhibition of glucokinase by long chain acyl coenzymes A below the critical micelle concentration. , 1982, The Journal of biological chemistry.

[41]  K. Jungermann,et al.  Modulation by insulin and glucagon of the activation of glycogenolysis by perivascular nerve stimulation in the perfused rat liver , 1982, FEBS letters.

[42]  K. Jungermann,et al.  Heterogeneous distribution of phosphoenolpyruvate carboxykinase in rat liver parenchyma, isolated, and cultured hepatocytes. , 1982, European journal of cell biology.

[43]  N. Abumrad,et al.  Absorption and disposition of a glucose load in the conscious dog. , 1982, The American journal of physiology.

[44]  K. Jungermann,et al.  The glucose/glucose-6-phosphate cycle in the periportal and perivenous zone of rat liver. , 1982, European journal of biochemistry.

[45]  W. Fischer,et al.  Reciprocal distribution of hexokinase and glucokinase in the periportal and perivenous zone of the rat liver acinus. , 1982, Hoppe-Seyler's Zeitschrift fur physiologische Chemie.

[46]  K. Jungermann,et al.  Modulation of the glucagon-dependent induction of phosphoenolpyruvate carboxykinase and tyrosine aminotransferase by arterial and venous oxygen concentrations in hepatocyte cultures. , 1981, European journal of biochemistry.

[47]  A. Beynen,et al.  Control of glycogen metabolism by insulin in isolated hepatocytes. , 1981, Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme.

[48]  P. Walter,et al.  Short-term stimulation of net glycogen production by insulin in rat hepatocytes. , 1981, Biochimica et biophysica acta.

[49]  M. Speth,et al.  Hormone-induced effects on the rat liver microsomal glucose-6-phosphatase system in vitro. , 1981, Biochemical and biophysical research communications.

[50]  K. Jungermann,et al.  Induction of phosphoenolpyruvate carboxykinase by sympathetic agents in primary cultures of adult rat hepatocytes. , 1981, Biochemical and biophysical research communications.

[51]  J. Gumucio,et al.  Functional implications of liver cell heterogeneity , 1981 .

[52]  W. Lautt Hepatic nerves: a review of their functions and effects. , 1980, Canadian journal of physiology and pharmacology.

[53]  V. Potter,et al.  Scanning microdensitometry of glycogen zonation in the livers of rats adapted to a controlled feeding schedule and to 30, 60, or 90% casein diets. , 1980, The American journal of anatomy.

[54]  N. Katz,et al.  Induction of glucokinase by insulin under the permissive action of dexamethasone in primary rat hepatocyte cultures. , 1979, Biochemical and biophysical research communications.

[55]  J. E. Felíu,et al.  Control of gluconeogenesis and of enzymes of glycogen metabolism in isolated rat hepatocytes. A parallel study of the effect of phenylephrine and of glucagon. , 1978, The Biochemical journal.

[56]  Gradients of O2 concentration in hepatocytes. , 1978, The Journal of biological chemistry.

[57]  K. Jungermann,et al.  Heterogeneity of liver parenchymal cells , 1978 .

[58]  R. McCuskey,et al.  Intrahepatic distribution of nerves in the rat , 1978, The Anatomical record.

[59]  J. Avruch,et al.  Insulin regulation of hepatic glycogen synthase and phosphorylase. , 1978, Biochemistry.

[60]  R. Bittner,et al.  Developmental changes in the levels of hepatic enzymes and their relation to metabolic functions. , 1978, Advances in enzyme regulation.

[61]  K. Jungermann,et al.  Increase of the gluconeogenic and decrease of the glycolytic capacity of rat liver with a change of the metabolic zonation after partial hepatectomy. , 1978, Hoppe-Seyler's Zeitschrift fur physiologische Chemie.

[62]  K. Jungermann,et al.  Heterogeneous reciprocal localization of fructose‐1,6‐bis‐phosphatase and of glucokinase in microdissected periportal and perivenous rat liver tissue , 1977, FEBS letters.

[63]  W. Forssmann,et al.  Hepatocyte innervation in primates , 1977, The Journal of cell biology.

[64]  K. Jungermann,et al.  Heterogeneous distribution of glucose‐6‐phosphatase in microdissected periportal and perivenous rat liver tissue , 1977, FEBS letters.

[65]  R. Thauer,et al.  Energy Conservation in Chemotrophic Anaerobic Bacteria , 1977, Bacteriological reviews.

[66]  K. Jungermann,et al.  POSSIBLE METABOLIC ZONATION OF LIVER PARENCHYMA INTO GLUCOGENIC AND GLYCOLYTIC HEPATOCYTES , 1977 .

[67]  K. Jungermann,et al.  Perinatal development of the metabolic zonation of hamster liver parenchyma , 1976, FEBS letters.

[68]  K. Jungermann,et al.  Autoregulatory shift from fructolysis to lactate gluconeogenisis in rat hepatocyte suspensions. The problem of metabolic zonation of liver parenchyma. , 1976, Hoppe-Seyler's Zeitschrift fur physiologische Chemie.

[69]  W. Guder,et al.  Liver cell heterogeneity. The distribution of pyruvate kinase and phosphoenolpyruvate carboxykinase (GTP) in the liver lobule of fed and starved rats. , 1976, Hoppe-Seyler's Zeitschrift fur physiologische Chemie.

[70]  F. Bontemps,et al.  The effects of glucose and of potassium ions on the interconversion of the two forms of glycogen phosphorylase and of glycogen synthetase in isolated rat liver preparations. , 1975, The Biochemical journal.

[71]  J. Oliver,et al.  Uptake and supply of purine compounds by the liver. , 1975, The American journal of physiology.

[72]  T. Shimazu,et al.  Effects of hypothalamic stimulation on gluconeogenesis and glycolysis in rat liver. , 1975, The American journal of physiology.

[73]  P. Felig,et al.  Influence of Oral Glucose Ingestion on Splanchnic Glucose and Gluconeogenic Substrate Metabolism in Man , 1975, Diabetes.

[74]  P. Walker,et al.  Diurnal rhythms of hepatic carbohydrate metabolism during development of the rat. , 1974, The Biochemical journal.

[75]  A. Harris,et al.  Inductive functions of the nervous system. , 1974, Annual review of physiology.

[76]  F. Welsh CHANGES IN DISTRIBUTION OF ENZYMES WITHIN THE LIVER LOBULE DURING ADAPTIVE INCREASES , 1972, The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society.

[77]  E. Taylor,et al.  Glycogen synthesis in the perfused liver of the starved rat. , 1971, The Biochemical journal.

[78]  J. Olavarria,et al.  Recovery of the liver glycogen in fasted rats. , 1968, Biochimica et biophysica acta.

[79]  A. Loud A QUANTITATIVE STEREOLOGICAL DESCRIPTION OF THE ULTRASTRUCTURE OF NORMAL RAT LIVER PARENCHYMAL CELLS , 1968, The Journal of cell biology.

[80]  I. Karl,et al.  CELL HETEROGENEITY WITHIN THE HEPATIC LOBULE (QUANTITATIVE HISTOCHEMISTRY) , 1959, The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society.

[81]  A. Novikoff,et al.  CELL HETEROGENEITY WITHIN THE HEPATIC LOBULE OF THE RAT (STAINING REACTIONS) , 1959, The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society.

[82]  H. Schumacher Histochemical distribution pattern of respiratory enzymes in the liver lobule. , 1957, Science.

[83]  Hers Hg The conversion of fructose-1-C14 and sorbitol-1-C14 to liver and muscle glycogen in the rat. , 1955 .