SCA1 transgenic mice: A model for neurodegeneration caused by an expanded CAG trinucleotide repeat
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Harry T Orr | H. Zoghbi | H. Orr | E. Burright | L. Duvick | H. Clark | R. Feddersen | Huda Y Zoghbi | Lisa A Duvick | H Brent Clark | Eric N Burright | Antonio Servadio | Toni Matilla | Rodney M Feddersen | Wael S Yunis | A. Servadio | Wael S. Yunis | T. Matilla
[1] K. Arai,et al. SR alpha promoter: an efficient and versatile mammalian cDNA expression system composed of the simian virus 40 early promoter and the R-U5 segment of human T-cell leukemia virus type 1 long terminal repeat , 1988, Molecular and cellular biology.
[2] A. Beaudet,et al. Spinocerebellar ataxia: Variable age of onset and linkage to human leukocyte antigen in a large kindred , 1988, Annals of neurology.
[3] O. Onodera,et al. Unstable expansion of CAG repeat in hereditary dentatorubral–pallidoluysian atrophy (DRPLA) , 1994, Nature Genetics.
[4] X. Estivill,et al. Presymptomatic analysis of spinocerebellar ataxia type 1 (SCA1) via the expansion of the SCA1 CAG-repeat in a large pedigree displaying anticipation and parental male bias. , 1993, Human molecular genetics.
[5] H. Orr,et al. Disrupted cerebellar cortical development and progressive degeneration of Purkinje cells in SV40 T antigen transgenic mice , 1992, Neuron.
[6] H M Cann,et al. The gene for autosomal dominant spinocerebellar ataxia (SCA1) maps telomeric to the HLA complex and is closely linked to the D6S89 locus in three large kindreds. , 1991, American journal of human genetics.
[7] R. Duvoisin,et al. The Olivopontocerebellar Atrophies , 1982 .
[8] H. Zoghbi,et al. Spinocerebellar ataxia type 1. , 1995, Clinical neuroscience.
[9] Harry T. Orr,et al. Identification and characterization of the gene causing type 1 spinocerebellar ataxia , 1994, Nature Genetics.
[10] Manish S. Shah,et al. A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes , 1993, Cell.
[11] K. Fischbeck,et al. Androgen receptor gene mutations in X-linked spinal and bulbar muscular atrophy , 1991, Nature.
[12] J. Merlie,et al. Transgene detection in unpurified mouse tail DNA by polymerase chain reaction. , 1991, BioTechniques.
[13] B. Hogan,et al. Manipulating the mouse embryo: A laboratory manual , 1986 .
[14] J. Santamaria,et al. A family with adult spinal and bulbar muscular atrophy, X-linked inheritance and associated testicular failure , 1983, Journal of the Neurological Sciences.
[15] Huda Y. Zoghbi,et al. Expansion of an unstable trinucleotide CAG repeat in spinocerebellar ataxia type 1 , 1993, Nature Genetics.
[16] E. Mugnaini,et al. Dynamic organization of developing Purkinje cells revealed by transgene expression. , 1991, Science.
[17] A. C. Chinault,et al. Mapping and cloning of the critical region for the spinocerebellar ataxia type 1 gene (SCA1) in a yeast artificial chromosome contig spanning 1.2 Mb. , 1993, Genomics.
[18] J. Penney,et al. Homozygotes for Huntington's disease , 1987, Nature.
[19] S. Zackson,et al. A promoter that drives transgene expression in cerebellar Purkinje and retinal bipolar neurons. , 1990, Science.
[20] T. Roderick,et al. FVB/N: an inbred mouse strain preferable for transgenic analyses. , 1991, Proceedings of the National Academy of Sciences of the United States of America.
[21] H. Willard,et al. Complete deletion of the androgen receptor gene: definition of the null phenotype of the androgen insensitivity syndrome and determination of carrier status. , 1992, The Journal of clinical endocrinology and metabolism.
[22] S. Weissman,et al. Organization and transcription of the simian virus 40 genome. , 1979, Current topics in microbiology and immunology.
[23] A. Marquis Gacy,et al. Trinucleotide repeats that expand in human disease form hairpin structures in vitro , 1995, Cell.
[24] M. Meyn,et al. Molecular definition of the smallest region of deletion overlap in the Wolf-Hirschhorn syndrome. , 1992, American journal of human genetics.
[25] J. Haines,et al. Spinocerebellar ataxia in a large kindred , 1984, Neurology.
[26] H. Orr,et al. In Vivo Viability of Postmitotic Purkinje Neurons Requires pRb Family Member Function , 1995, Molecular and Cellular Neuroscience.
[27] Shigenobu Nakamura,et al. CAG expansions in a novel gene for Machado-Joseph disease at chromosome 14q32.1 , 1994, Nature Genetics.
[28] K. Fischbeck,et al. Stability of an expanded trinucleotide repeat in the androgen receptor gene in transgenic mice , 1995, Nature Genetics.
[29] H. Orr,et al. Localization of the autosomal dominant HLA-linked spinocerebellar ataxia (SCA1) locus, in two kindreds, within an 8-cM subregion of chromosome 6p. , 1991, American journal of human genetics.
[30] A. Beaudet,et al. The gene for autosomal dominant spinocerebellar ataxia (SCA1) maps centromeric to D6S89 and shows no recombination, in nine large kindreds, with a dinucleotide repeat at the AM10 locus. , 1993, American journal of human genetics.
[31] H. Zoghbi,et al. Gametic and somatic tissue–specific heterogeneity of the expanded SCA1 CAG repeat in spinocerebellar ataxia type 1 , 1995, Nature Genetics.
[32] A. Sano,et al. Dentatorubral and pallidoluysian atrophy expansion of an unstable CAG trinucleotide on chromosome 12p , 1994, Nature Genetics.
[33] Koeppen Ah,et al. The neuropathology of olivopontocerebellar atrophy. , 1984 .
[34] P. Chomczyński,et al. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. , 1987, Analytical biochemistry.
[35] H. Zoghbi,et al. Expression analysis of the ataxin–1 protein in tissues from normal and spinocerebellar ataxia type 1 individuals , 1995, Nature Genetics.
[36] A. Koeppen,et al. The neuropathology of olivopontocerebellar atrophy. , 1984, Advances in neurology.
[37] H. Zoghbi,et al. Evidence for a mechanism predisposing to intergenerational CAG repeat instability in spinocerebellar ataxia type I , 1993, Nature Genetics.
[38] A. Harding,et al. Effect of trinucleotide repeat length and parental sex on phenotypic variation in spinocerebellar ataxia I. , 1994, American journal of human genetics.
[39] M. Pericak-Vance,et al. The Haw River Syndrome: Dentatorubropallidoluysian atrophy (DRPLA) in an African–American family , 1994, Nature Genetics.
[40] H. Orr,et al. Purkinje cell protein-2 regulatory regions and transgene expression in cerebellar compartments. , 1991, Genes & development.
[41] H. Zoghbi,et al. Molecular and clinical correlations in spinocerebellar ataxia type I: evidence for familial effects on the age at onset. , 1994, American journal of human genetics.
[42] S. Floresco,et al. Targeted disruption of the Huntington's disease gene results in embryonic lethality and behavioral and morphological changes in heterozygotes , 1995, Cell.