Neuron navigator 2 overexpression indicates poor prognosis of colorectal cancer and promotes invasion through the SSH1L/cofilin-1 pathway

[1]  C. Kirkpatrick,et al.  The relevance of cell type- and tumor zone-specific VEGFR-2 activation in locally advanced colon cancer , 2015, Journal of Experimental & Clinical Cancer Research.

[2]  A. Jemal,et al.  Global cancer statistics, 2012 , 2015, CA: a cancer journal for clinicians.

[3]  F. Offner,et al.  Tumor budding in colorectal cancer revisited: results of a multicenter interobserver study , 2015, Virchows Archiv.

[4]  Hua-mei Tang,et al.  Elevated kinesin family member 26B is a prognostic biomarker and a potential therapeutic target for colorectal cancer , 2015, Journal of Experimental & Clinical Cancer Research.

[5]  A. Paradiso,et al.  KRAS mutations in tumor tissue and plasma by different assays predict survival of patients with metastatic colorectal cancer , 2014, Journal of experimental & clinical cancer research : CR.

[6]  T. Tabata,et al.  The NAV2 homolog Sickie regulates F-actin-mediated axonal growth in Drosophila mushroom body neurons via the non-canonical Rac-Cofilin pathway , 2014, Development.

[7]  D. Ichikawa,et al.  Efficacy of perioperative chemotherapy in patients with colorectal cancer undergoing hepatectomy for resectable synchronous liver metastasis. , 2014, Hepato-gastroenterology.

[8]  Chun-tao Wu,et al.  Stathmin destabilizing microtubule dynamics promotes malignant potential in cancer cells by epithelial-mesenchymal transition. , 2014, Hepatobiliary & pancreatic diseases international : HBPD INT.

[9]  R. Bergan,et al.  Diminished expression of h2-calponin in prostate cancer cells promotes cell proliferation, migration and the dependence of cell adhesion on substrate stiffness , 2014, FEBS open bio.

[10]  Isobel Leake Colorectal cancer: Understanding the routes of metastasis in colorectal cancer , 2014, Nature Reviews Gastroenterology &Hepatology.

[11]  Benjamin J. Raphael,et al.  Mutational landscape and significance across 12 major cancer types , 2013, Nature.

[12]  M. Vitolo,et al.  Loss of PTEN induces microtentacles through PI3K-independent activation of cofilin , 2013, Oncogene.

[13]  I. Shih,et al.  Gene expression signatures differentiate uterine endometrial stromal sarcoma from leiomyosarcoma. , 2013, Gynecologic oncology.

[14]  H. Buhr,et al.  Increased Pontin expression is a potential predictor for outcome in sporadic colorectal carcinoma. , 2012, Oncology reports.

[15]  Steven J. M. Jones,et al.  Comprehensive molecular characterization of human colon and rectal cancer , 2012, Nature.

[16]  Arthur T. Johnson,et al.  Quantitative comparison of immunohistochemical staining measured by digital image analysis versus pathologist visual scoring , 2012, Diagnostic Pathology.

[17]  M. Pollheimer,et al.  Tumor Budding is an Independent Predictor of Outcome in AJCC/UICC Stage II Colorectal Cancer , 2012, Annals of Surgical Oncology.

[18]  S. Knuutila,et al.  Potential role of a navigator gene NAV3 in colorectal cancer , 2011, British Journal of Cancer.

[19]  A. Ridley,et al.  RhoA and RhoC have distinct roles in migration and invasion by acting through different targets , 2011, The Journal of cell biology.

[20]  A. Jemal,et al.  Global Cancer Statistics , 2011 .

[21]  J. Sedivy,et al.  Proteomic profiling of Myc-associated proteins , 2010, Cell cycle.

[22]  B. Zhou,et al.  PTEN loss induces epithelial--mesenchymal transition in human colon cancer cells. , 2009, Anticancer research.

[23]  Erin M. Conn,et al.  Evaluation of metastatic and angiogenic potentials of human colon carcinoma cells in chick embryo model systems , 2009, Clinical & Experimental Metastasis.

[24]  D. Baillie,et al.  The cell migration molecule UNC-53/NAV2 is linked to the ARP2/3 complex by ABI-1 , 2009, Development.

[25]  M. Barr,et al.  The atRA‐responsive gene neuron navigator 2 functions in neurite outgrowth and axonal elongation , 2008, Developmental neurobiology.

[26]  Guojun Sheng,et al.  RhoA and microtubule dynamics control cell–basement membrane interaction in EMT during gastrulation , 2008, Nature Cell Biology.

[27]  A. Belayew,et al.  The Helicase-Like Transcription Factor and its implication in cancer progression , 2008, Cellular and Molecular Life Sciences.

[28]  J. Condeelis,et al.  EGF-induced PIP2 hydrolysis releases and activates cofilin locally in carcinoma cells , 2007, The Journal of cell biology.

[29]  H. Malik,et al.  Predictors of early disease recurrence following hepatic resection for colorectal cancer metastasis. , 2007, European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology.

[30]  R. Labianca,et al.  Endpoints in adjuvant treatment trials: a systematic review of the literature in colon cancer and proposed definitions for future trials. , 2007, Journal of the National Cancer Institute.

[31]  Alissa M. Weaver,et al.  Cortactin is an essential regulator of matrix metalloproteinase secretion and extracellular matrix degradation in invadopodia. , 2007, Cancer research.

[32]  F. Prall Tumour budding in colorectal carcinoma , 2007, Histopathology.

[33]  H. Ueno,et al.  Differential Prognostic Significance of Morphologic Invasive Markers in Colorectal Cancer: Tumor Budding and Cytoplasmic Podia , 2006, Diseases of the colon and rectum.

[34]  T. Uemura,et al.  A pathway of neuregulin-induced activation of cofilin-phosphatase Slingshot and cofilin in lamellipodia , 2004, The Journal of cell biology.

[35]  S. Mocellin,et al.  Treatment options for liver metastases from colorectal cancer. , 2003, Journal of experimental & clinical cancer research : CR.

[36]  Yasuyuki Shima,et al.  Differential activities, subcellular distribution and tissue expression patterns of three members of Slingshot family phosphatases that dephosphorylate cofilin , 2003, Genes to cells : devoted to molecular & cellular mechanisms.

[37]  Yusuke Nakamura,et al.  Isolation of HELAD1, a novel human helicase gene up-regulated in colorectal carcinomas , 2002, Oncogene.

[38]  J. Vandekerckhove,et al.  unc-53 controls longitudinal migration in C. elegans. , 2002, Development.

[39]  C. Buesa,et al.  Neuron navigator: a human gene family with homology to unc-53, a cell guidance gene from Caenorhabditis elegans. , 2002, Genomics.

[40]  R. Merrill,et al.  A mammalian homolog of unc-53 is regulated by all-trans retinoic acid in neuroblastoma cells and embryos , 2002, Proceedings of the National Academy of Sciences of the United States of America.

[41]  W. Dinjens,et al.  A comparative evaluation of various invasion assays testing colon carcinoma cell lines , 1999, British Journal of Cancer.

[42]  J. Bamburg Proteins of the ADF/cofilin family: essential regulators of actin dynamics. , 1999, Annual review of cell and developmental biology.

[43]  A. Jemal,et al.  Global cancer statistics , 2011, CA: a cancer journal for clinicians.