Linking secondary metabolites to biosynthesis genes in the fungal endophyte Cyanodermella asteris: The anti-cancer bisanthraquinone skyrin.

[1]  Jian Ni,et al.  Aloe‐emodin: A review of its pharmacology, toxicity, and pharmacokinetics , 2019, Phytotherapy research : PTR.

[2]  T. Weber,et al.  Cyanodermella asteris sp. nov. (Ostropales) from the inflorescence axis of Aster tataricus , 2017 .

[3]  Susumu Goto,et al.  Type III Polyketide Synthases: Functional Classification and Phylogenomics , 2017, Chembiochem : a European journal of chemical biology.

[4]  Anil Kumar,et al.  Molecular Approaches to Screen Bioactive Compounds from Endophytic Fungi , 2016, Front. Microbiol..

[5]  J. Gloer,et al.  Biologically Active Secondary Metabolites from the Fungi , 2016, Microbiology spectrum.

[6]  C. Müller,et al.  Anthraquinones As Pharmacological Tools and Drugs , 2016, Medicinal research reviews.

[7]  Yedukondalu Nalli,et al.  Antimicrobial Potential of Thiodiketopiperazine Derivatives Produced by Phoma sp., an Endophyte of Glycyrrhiza glabra Linn. , 2016, Microbial Ecology.

[8]  In-Jung Lee,et al.  Sorokiniol: a new enzymes inhibitory metabolite from fungal endophyte Bipolaris sorokiniana LK12 , 2016, BMC Microbiology.

[9]  R. Cox,et al.  Elucidation of cladofulvin biosynthesis reveals a cytochrome P450 monooxygenase required for anthraquinone dimerization , 2016, Proceedings of the National Academy of Sciences.

[10]  Jian Ni,et al.  Emodin: A Review of its Pharmacology, Toxicity and Pharmacokinetics , 2016, Phytotherapy research : PTR.

[11]  R. Buonfiglio,et al.  Secondary metabolites from cetrarioid lichens: Chemotaxonomy, biological activities and pharmaceutical potential. , 2016, Phytomedicine : international journal of phytotherapy and phytopharmacology.

[12]  Qiao-yan Zhang,et al.  New cytotoxic compounds of endophytic fungus Alternaria sp. isolated from Broussonetia papyrifera (L.) Vent. , 2016, Fitoterapia.

[13]  Marnix H Medema,et al.  Comprehensive curation and analysis of fungal biosynthetic gene clusters of published natural products. , 2016, Fungal genetics and biology : FG & B.

[14]  L. Dufossé,et al.  Anthraquinones and Derivatives from Marine-Derived Fungi: Structural Diversity and Selected Biological Activities , 2016, Marine drugs.

[15]  J. Blom,et al.  Genome analysis of the sugar beet pathogen Rhizoctonia solani AG2-2IIIB revealed high numbers in secreted proteins and cell wall degrading enzymes , 2016, BMC Genomics.

[16]  J. Boustie,et al.  Xanthones of Lichen Source: A 2016 Update , 2016, Molecules.

[17]  P. R. Sharma,et al.  Secondary Metabolites from Endophytic Fungus Penicillium pinophilum Induce ROS-Mediated Apoptosis through Mitochondrial Pathway in Pancreatic Cancer Cells , 2016, Planta Medica.

[18]  Shao-Hua Wu,et al.  A new dimeric anthraquinone from endophytic Talaromyces sp. YE3016 , 2016, Natural product research.

[19]  Y. Ni,et al.  Synthesis and Evaluation of 131I-Skyrin as a Necrosis Avid Agent for Potential Targeted Radionuclide Therapy of Solid Tumors. , 2016, Molecular pharmaceutics.

[20]  P. Akilandeswari,et al.  Exploration of industrially important pigments from soil fungi , 2015, Applied Microbiology and Biotechnology.

[21]  Kai Blin,et al.  antiSMASH 3.0—a comprehensive resource for the genome mining of biosynthetic gene clusters , 2015, Nucleic Acids Res..

[22]  Nowsheen Shameem,et al.  Fungal endophytes as prolific source of phytochemicals and other bioactive natural products: A review. , 2015, Microbial pathogenesis.

[23]  Mian Zhang,et al.  Expectorant, antitussive, anti-inflammatory activities and compositional analysis of Aster tataricus. , 2015, Journal of ethnopharmacology.

[24]  J. Frisvad,et al.  Polyphasic taxonomy of the genus Talaromyces , 2014, Studies in mycology.

[25]  L. Dufossé,et al.  Filamentous fungi are large-scale producers of pigments and colorants for the food industry. , 2014, Current opinion in biotechnology.

[26]  Matthew Fraser,et al.  InterProScan 5: genome-scale protein function classification , 2014, Bioinform..

[27]  R. Cox,et al.  Secondary Metabolism and Biotrophic Lifestyle in the Tomato Pathogen Cladosporium fulvum , 2014, PloS one.

[28]  A. Goesmann,et al.  Construction of a Public CHO Cell Line Transcript Database Using Versatile Bioinformatics Analysis Pipelines , 2014, PloS one.

[29]  A. Taher,et al.  Synthesis of novel bis-anthraquinone derivatives and their biological evaluation as antitumor agents , 2013, Archives of pharmacal research.

[30]  Fungal anthraquinones , 2013, Applied Biochemistry and Microbiology.

[31]  T. J. Simpson.  Genetic and Biosynthetic Studies of the Fungal Prenylated Xanthone Shamixanthone and Related Metabolites in Aspergillus spp. Revisited , 2012, Chembiochem : a European journal of chemical biology.

[32]  N. Keller,et al.  Genome-Based Cluster Deletion Reveals an Endocrocin Biosynthetic Pathway in Aspergillus fumigatus , 2012, Applied and Environmental Microbiology.

[33]  U. Güldener,et al.  Endophytic Life Strategies Decoded by Genome and Transcriptome Analyses of the Mutualistic Root Symbiont Piriformospora indica , 2011, PLoS pathogens.

[34]  C. Townsend,et al.  New insights into the formation of fungal aromatic polyketides , 2010, Nature Reviews Microbiology.

[35]  Yanran Li,et al.  Classification, prediction, and verification of the regioselectivity of fungal polyketide synthase product template domains. , 2010, The Journal of biological chemistry.

[36]  Clay C C Wang,et al.  Characterization of the Aspergillus nidulans Monodictyphenone Gene Cluster , 2010, Applied and Environmental Microbiology.

[37]  Jason W. Labonte,et al.  Structural basis for biosynthetic programming of fungal aromatic polyketide cyclization , 2009, Nature.

[38]  S. Horinouchi,et al.  Physically discrete beta-lactamase-type thioesterase catalyzes product release in atrochrysone synthesis by iterative type I polyketide synthase. , 2009, Chemistry & biology.

[39]  C. Hertweck,et al.  The biosynthetic logic of polyketide diversity. , 2009, Angewandte Chemie.

[40]  Clay C C Wang,et al.  Identification and Characterization of the Asperthecin Gene Cluster of Aspergillus nidulans , 2008, Applied and Environmental Microbiology.

[41]  Elfie Stocker-Woergoetter.  Metabolic Diversity of Lichen‐Forming Ascomycetous Fungi: Culturing, Polyketide and Shikimate Metabolite Production, and PKS Genes , 2008 .

[42]  E. Stocker-Wörgötter.  Metabolic diversity of lichen-forming ascomycetous fungi: culturing, polyketide and shikimate metabolite production, and PKS genes. , 2008, Natural product reports.

[43]  Daniel W. Udwary,et al.  Identification of a starter unit acyl-carrier protein transacylase domain in an iterative type I polyketide synthase , 2006, Proceedings of the National Academy of Sciences.

[44]  Burkhard Morgenstern,et al.  Gene prediction in eukaryotes with a generalized hidden Markov model that uses hints from external sources , 2006, BMC Bioinformatics.

[45]  John E. Linz,et al.  Clustered Pathway Genes in Aflatoxin Biosynthesis , 2004, Applied and Environmental Microbiology.

[46]  Zhengtao Wang,et al.  Antioxidant activity of compounds from the medicinal herb Aster tataricus. , 2003, Comparative biochemistry and physiology. Toxicology & pharmacology : CBP.

[47]  R. Giegerich,et al.  GenDB--an open source genome annotation system for prokaryote genomes. , 2003, Nucleic acids research.

[48]  J. Clardy,et al.  Cytoskyrins A and B, new BIA active bisanthraquinones isolated from an endophytic fungus. , 2000, Organic letters.

[49]  H. Sandermann,et al.  A simple and efficient protocol for isolation of high molecular weight DNA from filamentous fungi, fruit bodies, and infected plant tissues. , 1992, Nucleic acids research.

[50]  B. Franck,et al.  Pilzinhaltstoffe, 32. Nachweis einer bicyclischen Zwischenstufe der Anthrachinon‐Biosynthese , 1981 .

[51]  U. Sankawa,et al.  Biosynthetic incorporation of emodin and emodinanthrone into the anthraquinonoids of and . , 1973 .

[52]  L. Vining,et al.  STUDIES IN THE BIOCHEMISTRY OF MICROORGANISMS: PART 117. SEPEDONIN, A TROPOLONE METABOLITE OF SEPEDONIUM CHRYSOSPERMUM FRIES , 1965 .

[53]  S. Shibata,et al.  Metabolic products of fungi. XIII. The structure of oxyskyrin. , 1957, Pharmaceutical bulletin.

[54]  H. Raistrick,et al.  Studies in the biochemistry of micro-organisms. 91. The colouring matters of Penicillium islandicum Sopp. 3. Skyrin and flavoskyrin. , 1954, The Biochemical journal.