Efficacy and tolerability of a double‐conjugated retinoid cream vs 1.0% retinol cream or 0.025% tretinoin cream in subjects with mild to severe photoaging

Topical retinoids are used to treat the visible signs of photoaging. While efficacious, they are irritating.

[1]  M. Casey,et al.  Development of Halo Nevi in a Lung Cancer Patient: A Novel Immune-Related Cutaneous Event from Atezolizumab. , 2017, Journal of drugs in dermatology : JDD.

[2]  A. Friedman,et al.  Skin Barrier Health: Regulation and Repair of the Stratum Corneum and the Role of Over-the-Counter Skin Care. , 2016, Journal of drugs in dermatology : JDD.

[3]  Z. Draelos,et al.  Novel retinoid ester in combination with salicylic acid for the treatment of acne , 2016, Journal of cosmetic dermatology.

[4]  A. Pellegrino,et al.  The Tolerability and Efficacy of a Three-product Anti-aging Treatment Regimen in Subjects with Moderate-to-severe Photodamage. , 2015, The Journal of clinical and aesthetic dermatology.

[5]  M. Lebwohl,et al.  A consensus approach to improving patient adherence and persistence with topical treatment for actinic keratosis , 2015, International journal of dermatology.

[6]  Z. Draelos,et al.  The skin health and beauty pyramid: a clinically based guide to selecting topical skincare products. , 2014, Journal of drugs in dermatology : JDD.

[7]  Jaishree Sharad Glycolic acid peel therapy – a current review , 2013, Clinical, cosmetic and investigational dermatology.

[8]  C. Cervellati,et al.  Annals of the New York Academy of Sciences Cutaneous Responses to Environmental Stressors , 2022 .

[9]  Fan Yang,et al.  Intracellular Proton-mediated Activation of TRPV3 Channels Accounts for the Exfoliation Effect of α-Hydroxyl Acids on Keratinocytes* , 2012, The Journal of Biological Chemistry.

[10]  R. Mehta,et al.  A randomized, double-blind, controlled comparative trial of the anti-aging properties of non-prescription tri-retinol 1.1% vs. prescription tretinoin 0.025%. , 2012, Journal of drugs in dermatology : JDD.

[11]  M. Kawashima,et al.  Acne Management in Japan: Study of Patient Adherence , 2011, Dermatology.

[12]  S. Feldman,et al.  Simplifying regimens promotes greater adherence and outcomes with topical acne medications: a randomized controlled trial. , 2010, Cutis.

[13]  M. Rendon,et al.  Evidence and considerations in the application of chemical peels in skin disorders and aesthetic resurfacing. , 2010, The Journal of clinical and aesthetic dermatology.

[14]  S. Bruce Cosmeceuticals for the attenuation of extrinsic and intrinsic dermal aging. , 2008, Journal of drugs in dermatology : JDD.

[15]  V. Patravale,et al.  Retinoids in the treatment of skin aging: an overview of clinical efficacy and safety , 2006, Clinical interventions in aging.

[16]  A. Rawlings,et al.  Effect of lactic acid isomers on keratinocyte ceramide synthesis, stratum corneum lipid levels and stratum corneum barrier function , 1996, Archives of Dermatological Research.

[17]  J. Saurat,et al.  Pharmacology of RALGA, a Mixture of Retinaldehyde and Glycolic Acid , 2005, Dermatology.

[18]  G. Grove,et al.  An evaluation of the moisturizing and anti-itch effects of a lactic acid and pramoxine hydrochloride cream. , 2004, Cutis.

[19]  S. Kang,et al.  Photoaging and tretinoin. , 1998, Dermatologic clinics.

[20]  W. Smith Epidermal and dermal effects of topical lactic acid. , 1996, Journal of the American Academy of Dermatology.

[21]  T. Hamilton,et al.  Two concentrations of topical tretinoin (retinoic acid) cause similar improvement of photoaging but different degrees of irritation. A double-blind, vehicle-controlled comparison of 0.1% and 0.025% tretinoin creams. , 1995, Archives of dermatology.

[22]  A M Kligman,et al.  Topical tretinoin for photoaged skin. , 1986, Journal of the American Academy of Dermatology.

[23]  Arnold Schwarzenegger The aging skin. , 1986, Dermatologic clinics.

[24]  A. Kligman,et al.  Topical retinoic acid enhances the repair of ultraviolet damaged dermal connective tissue. , 1984, Connective tissue research.

[25]  S. Fredricks AMERICAN SOCIETY FOR AESTHETIC PLASTIC SURGERY , 1970 .