论文信息 - Implementation of genomic medicine in a health care delivery system: A value proposition?

Implementation of genomic medicine in a health care delivery system: A value proposition?

The United States health care system is undergoing significant change and is seeking innovations in care delivery and reimbursement models that will lead to improved value for patients, providers, payers, and employers. Genomic medicine has the potential to be a disruptive innovation that if implemented intelligently can improve value. The article presents the perspective of the leaders of a large integrated healthcare delivery system regarding the decision to invest in implementation of genomic medicine. © 2014 Wiley Periodicals, Inc.

[1] W. Strodel,et al. Next-Generation Sequence Analysis of Genes Associated with Obesity and Nonalcoholic Fatty Liver Disease-Related Cirrhosis in Extreme Obesity , 2013, Human Heredity.

[2] D. Brooten. Methodological issues linking costs and outcomes. , 1997, Medical care.

[3] Clayton M. Christensen,et al. The Innovator's Prescription: A Disruptive Solution for Health Care , 2008 .

[4] Dan M. Roden,et al. Implementing genomic medicine in the clinic: the future is here , 2013, Genetics in Medicine.

[5] D. Carey,et al. High Allelic Burden of Four Obesity SNPs Is Associated With Poorer Weight Loss Outcomes Following Gastric Bypass Surgery , 2011, Obesity.

[6] Marc S. Williams,et al. Genomic medicine implementation: Learning by example , 2014, American journal of medical genetics. Part C, Seminars in medical genetics.

[7] P. Barnett,et al. Cost analysis in the Department of Veterans Affairs: consensus and future directions. , 1999, Medical care.

[8] R. McCARTER,et al. Association of Ghrelin Receptor Promoter Polymorphisms with Weight Loss Following Roux-en-Y Gastric Bypass Surgery , 2012, Obesity Surgery.

[9] J Lyle Bootman,et al. Value in health care. , 2006, Managed care interface.

[10] Melissa A. Basford,et al. The Electronic Medical Records and Genomics (eMERGE) Network: past, present, and future , 2013, Genetics in Medicine.