Potential roles for diatomists in nanotechnology.

Diatoms produce diverse three-dimensional structures that, due to their exponential rate of growth, may be of use in the manufacture of components for nanotechnology as an alternative to present linear lithographic techniques. Vapor replacement of the silicon permits the conversion of diatom silica valves and other structures to metal/ceramics, with no loss of structure. The literature on diatom nanotechnology is reviewed, along with suggestions on how diatomists might enhance this emerging technology. There is a need for a systematics based catalog of parts (via genomics technologies), improved diatom culture techniques, better understanding of the mechanisms of diatom morphogenesis and motility, and genetic manipulation, mutagenesis, and selection, as via the chemostat-like compustat. Given the self-motility of raphid diatoms, they could form the basis for industrially useful nanobots.

[1]  A. Grossman,et al.  Stable nuclear transformation of the diatomPhaeodactylum tricornutum , 1996, Molecular and General Genetics MGG.

[2]  Matthew B. Dickerson,et al.  Novel, Bioclastic Route to Self‐Assembled, 3D, Chemically Tailored Meso/Nanostructures: Shape‐Preserving Reactive Conversion of Biosilica (Diatom) Microshells , 2002 .

[3]  M. Hildebrand,et al.  Characterization of a silicon transporter gene family in Cylindrotheca fusiformis: sequences, expression analysis, and identification of homologs in other diatoms , 1998, Molecular and General Genetics MGG.

[4]  P. Mulvaney,et al.  THE STRUCTURE AND NANOMECHANICAL PROPERTIES OF THE ADHESIVE MUCILAGE THAT MEDIATES DIATOM‐SUBSTRATUM ADHESION AND MOTILITY 1 , 2003 .

[5]  L. Medlin,et al.  Evolution of the diatoms (Bacillariophyta). IV. A reconstruction of their age from small subunit rRNA coding regions and the fossil record. , 1996, Molecular phylogenetics and evolution.

[6]  R. Gordon,et al.  Beyond micromachining: the potential of diatoms. , 1999, Trends in biotechnology.

[7]  E. Cox.  MUCILAGE TUBE MORPHOLOGY OF THREE TUBE‐DWELLING DIATOMS AND ITS DIAGNOSTIC VALUE 1 , 1981 .

[8]  C. Zurzolo,et al.  Exploring bioinorganic pattern formation in diatoms. A story of polarized trafficking. , 2001, Plant physiology.

[9]  Chris Bowler,et al.  Revealing the molecular secrets of marine diatoms. , 2002, Annual review of plant biology.

[10]  R. Rappaport,et al.  Cytokinesis in animal cells. , 1996, International Review of Cytology.

[11]  Harald Fischer,et al.  TARGETING AND COVALENT MODIFICATION OF CELL WALL AND MEMBRANE PROTEINS HETEROLOGOUSLY EXPRESSED IN THE DIATOM CYLINDROTHECA FUSIFORMIS (BACILLARIOPHYCEAE) , 1999 .

[12]  C. Bowler,et al.  Molecular insights into the novel aspects of diatom biology , 2001, Cellular and Molecular Life Sciences CMLS.

[13]  M. Highley,et al.  Nanotechnology in bio/clinical analysis. , 2000, Journal of chromatography. B, Biomedical sciences and applications.

[14]  E. Jarvis,et al.  GENETIC TRANSFORMATION OF THE DIATOMS CYCLOTELLA CRYPTICA AND NAVICULA SAPROPHILA , 1995 .

[15]  L Boddy,et al.  Pattern recognition in flow cytometry. , 2001, Cytometry.

[16]  R. Gordon,et al.  Centric diatom morphogenesis: a model based on a DLA algorithm investigating the potential role of microtubules. , 1999, Biochimica et biophysica acta.

[17]  K. Cooksey,et al.  Chemical signal-response in diatoms of the genus Amphora , 1988 .

[18]  Matthew M. Ferris,et al.  Quantitative intercomparison of transmission electron microscopy, flow cytometry, and epifluorescence microscopy for nanometric particle analysis. , 2002, Analytical biochemistry.

[19]  Rajesh R Naik,et al.  Silica-precipitating peptides isolated from a combinatorial phage display peptide library. , 2002, Journal of nanoscience and nanotechnology.

[20]  C. Bowler,et al.  Diatomics: toward diatom functional genomics. , 2005, Journal of nanoscience and nanotechnology.

[21]  N. Kröger,et al.  Silica-precipitating Peptides from Diatoms , 2001, The Journal of Biological Chemistry.

[22]  T. Coradin,et al.  Interactions of amino-containing peptides with sodium silicate and colloidal silica: A biomimetic approach of silicification , 2002 .

[23]  H. Morowitz.  The Emergence of Everything: How the World Became Complex , 2002 .

[24]  R. Gordon,et al.  On square holes in pennate diatoms , 1990 .

[25]  Nicholas H. Putnam,et al.  The Genome of the Diatom Thalassiosira Pseudonana: Ecology, Evolution, and Metabolism , 2004, Science.

[26]  A. Kerlavage,et al.  Complementary DNA sequencing: expressed sequence tags and human genome project , 1991, Science.

[27]  J. Harper,et al.  Measurements of diatom adhesion and their relationship with movement , 1967 .

[28]  A. Estes,et al.  VALVE ABNORMALITIES IN DIATOM CLONES MAINTAINED IN LONG-TERM CULTURE , 1994 .

[29]  J Philip McCoy,et al.  Basic principles of flow cytometry. , 2002, Hematology/oncology clinics of North America.

[30]  R. Gordon.  A retaliatory role for algal projectiles, with implications for the mechanochemistry of diatom gliding motility* , 1987 .

[31]  M. Gretz,et al.  Extracellular matrix assembly in diatoms (Bacillariophyceae). iv. ultrastructure of Achnanthes longipes and Cymbella cistula as revealed by high‐pressure freezing/freeze substituton and cryo‐field emission scanning electron microscopy  , 2000 .

[32]  Thomas Scheper,et al.  Flow cytometry in biotechnology , 2001, Applied Microbiology and Biotechnology.

[33]  N. Kröger,et al.  Species-specific polyamines from diatoms control silica morphology. , 2000, Proceedings of the National Academy of Sciences of the United States of America.

[34]  K. M. Entwistle.  Basic principles of the finite element method , 1999 .

[35]  J M Rhodes.  Colorectal cancer screening in the UK: Joint Position Statement by the British Society of Gastroenterology, the Royal College of Physicians, and the Association of Coloproctology of Great Britain and Ireland , 2000, Gut.

[36]  C. Lowe,et al.  Nanobiotechnology: the fabrication and applications of chemical and biological nanostructures. , 2000, Current opinion in structural biology.

[37]  David W. Tomlin,et al.  Ultrafast holographic nanopatterning of biocatalytically formed silica , 2001, Nature.

[38]  R. Gordon,et al.  Diatom morphogenesis: natural fractal fabrication of a complex microstructure , 1988, Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society.

[39]  A. Falciatore,et al.  Transformation of Nonselectable Reporter Genes in Marine Diatoms , 1999, Marine Biotechnology.

[40]  H. D. Buf,et al.  Automatic diatom identification , 2002 .

[41]  E. G. Vrieling,et al.  Growth and silica content of the diatoms Thalassiosira weissflogii and Navicula salinarum at different salinities and enrichments with aluminium , 1999 .

[42]  P. Demers,et al.  Radiographic evidence of silicosis risk in the diatomaceous earth industry. , 1998, American journal of respiratory and critical care medicine.

[43]  Victor Smetacek,et al.  Architecture and material properties of diatom shells provide effective mechanical protection , 2003, Nature.

[44]  K. Cooksey,et al.  Can diatoms sense surfaces? State of our knowledge , 1992 .

[45]  J. Parkinson,et al.  400000 nematode ESTs on the Net. , 2003, Trends in parasitology.

[46]  E. G. Vrieling,et al.  SILICON DEPOSITION IN DIATOMS: CONTROL BY THE pH INSIDE THE SILICON DEPOSITION VESICLE , 1999 .

[47]  A. Kamatani,et al.  Resting spore formation and phosphorus composition of the marine diatom Chaetoceros pseudocurvisetus under various nutrient conditions , 1995 .

[48]  G. Ozin,et al.  Large-scale synthesis of a silicon photonic crystal with a complete three-dimensional bandgap near 1.5 micrometres , 2000, Nature.

[49]  N. Kröger,et al.  Polycationic peptides from diatom biosilica that direct silica nanosphere formation. , 1999, Science.

[50]  M. Gretz,et al.  EFFECTS OF BROMIDE AND IODIDE ON STALK SECRETION IN THE BIOFOULING DIATOM ACHNANTHES LONGIPES (BACILLARIOPHYCEAE) 1 , 1995 .

[51]  Jean-Christophe Olivo-Marin,et al.  Active contours applied to the shape and motion analysis of amoeba , 2001, SPIE Optics + Photonics.

[52]  Robert J Olson,et al.  Flow cytometric determination of size and complex refractive index for marine particles: comparison with independent and bulk estimates. , 2003, Applied optics.

[53]  H. Kling.  Asterionella formosa Ralfs: the process of rapid size reduction and its possible ecological significance , 1993 .

[54]  N. Hampp,et al.  Nanostructure of Diatom Silica Surfaces and of Biomimetic Analogues , 2002 .

[55]  Mark Hildebrand,et al.  A gene family of silicon transporters , 1997, Nature.

[56]  Marina G. Potapova,et al.  THE NATURAL LIFE CYCLE IN WILD POPULATIONS OF DIATOMA MONILIFORMIS (BACILLARIOPHYCEAE) AND ITS DISRUPTION IN AN ABERRANT ENVIRONMENT 1 , 1997 .

[57]  C. S. Chen,et al.  Geometric control of cell life and death. , 1997, Science.

[58]  R. W. Drum.  Petrifaction of Plant Tissue in the Laboratory , 1968, Nature.

[59]  R. Rachel,et al.  Characterization of a 200-kDa diatom protein that is specifically associated with a silica-based substructure of the cell wall. , 1997, European journal of biochemistry.

[60]  R. Gordon,et al.  MAKING WAVES: THE PARADIGMS OF DEVELOPMENTAL BIOLOGY AND THEIR IMPACT ON ARTIFICIAL LIFE AND EMBRYONICS , 2001, Cybern. Syst..

[61]  Engel G. Vrieling,et al.  LOCATION AND EXPRESSION OF FRUSTULINS IN THE PENNATE DIATOMS CYLINDROTHECA FUSIFORMIS, NAVICULA PELLICULOSA, AND NAVICULA SALINARUM (BACILLARIOPHYCEAE) , 1999 .

[62]  A. Daar,et al.  ‘Mind the gap’: science and ethics in nanotechnology , 2003, The Ethics of Nanotechnology, Geoengineering and Clean Energy.

[63]  V. Chepurnov,et al.  A STUDY OF VARIATION IN VALVE MORPHOLOGY OF THE DIATOM CYCLOTELLA MENEGHINIANA IN MONOCLONAL CULTURES: EFFECT OF AUXOSPORE FORMATION AND DIFFERENT SALINITY CONDITIONS , 1999 .

[64]  Mark Hildebrand,et al.  SILICON METABOLISM IN DIATOMS: IMPLICATIONS FOR GROWTH  , 2000 .

[65]  N. Kröger,et al.  Frustulins: domain conservation in a protein family associated with diatom cell walls. , 1996, European journal of biochemistry.

[66]  A. Grossman,et al.  Transformation of the diatom Phaeodactylum tricornutum (Bacillariophyceae) with a variety of selectable marker and reporter genes , 2000 .

[67]  P. Harber,et al.  Radiographic and spirometric findings in diatomaceous earth workers. , 1998, Journal of occupational and environmental medicine.

[68]  M. Hildebrand,et al.  Silicon-responsive cDNA clones isolated from the marine diatom Cylindrotheca fusiformis. , 1993, Gene.

[69]  M. Madou.  Fundamentals of microfabrication : the science of miniaturization , 2002 .

[70]  Mohammad A. Karim,et al.  Optical Computing: An Introduction , 1992 .

[71]  N. C. MacDonald,et al.  Optimal shape design of an electrostatic comb drive in microelectromechanical systems , 1998 .

[72]  M. Sipper,et al.  Toward robust integrated circuits: The embryonics approach , 2000, Proceedings of the IEEE.

[73]  C. Hamm,et al.  The evolution of advanced mechanical defenses and potential technological applications of diatom shells. , 2005, Journal of nanoscience and nanotechnology.

[74]  H. Claustre,et al.  Effects of temperature, nitrogen, and light limitation on the optical properties of the marine diatom Thalassiosira pseudonana , 2002 .

[75]  P. Roessler.  More tools for diatom molecular biology research , 2000 .

[76]  N. Chaffey,et al.  The cytoskeleton facilitates a three-dimensional symplasmic continuum in the long-lived ray and axial parenchyma cells of angiosperm trees , 2001, Planta.

[77]  R. Gordon,et al.  A capillarity mechanism for diatom gliding locomotion. , 1970, Proceedings of the National Academy of Sciences of the United States of America.

[78]  T. Okita,et al.  Role of silicon on diatom metabolism. IX. Differential synthesis of DNA polymerases and DNA-binding proteins during silicate starvation and recovery in Cylindrotheca fusiformis. , 1978, Biochimica et biophysica acta.