Apicoplast fatty acid synthesis is essential for organelle biogenesis and parasite survival in Toxoplasma gondii
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B. Striepen | Boris Striepen | J. Mazumdar | Jolly Mazumdar | Emma H Wilson | Kate Masek | Christopher A Hunter | K. Masek | Emma H Wilson | Christopher A Hunter
[1] Joachim Schachtner,et al. Toxoplasma gondii scavenges host‐derived lipoic acid despite its de novo synthesis in the apicoplast , 2006, The EMBO journal.
[2] Timm Maier,et al. Architecture of Mammalian Fatty Acid Synthase at 4.5 Å Resolution , 2006, Science.
[3] E. Maréchal,et al. Toxoplasma gondii acyl-lipid metabolism: de novo synthesis from apicoplast-generated fatty acids versus scavenging of host cell precursors. , 2006, The Biochemical journal.
[4] I. Coppens. Contribution of host lipids to Toxoplasma pathogenesis , 2006, Cellular microbiology.
[5] J. Hyde,et al. A glycine-cleavage complex as part of the folate one-carbon metabolism of Plasmodium falciparum. , 2005, Trends in parasitology.
[6] G. McFadden,et al. The malaria parasite Plasmodium falciparum has only one pyruvate dehydrogenase complex, which is located in the apicoplast , 2004, Molecular microbiology.
[7] T. Ramya,et al. 'FAS't inhibition of malaria. , 2004, The Biochemical journal.
[8] P. T. Englund,et al. Multiple Triclosan Targets in Trypanosoma brucei , 2004, Eukaryotic Cell.
[9] S. Müller,et al. The human malaria parasite Plasmodium falciparum has distinct organelle‐specific lipoylation pathways , 2004, Molecular microbiology.
[10] G. Zhu,et al. Current Progress in the Fatty Acid Metabolism in Cryptosporidium parvum1 , 2004, The Journal of eukaryotic microbiology.
[11] J. Keithly,et al. Expression and functional characterization of a giant Type I fatty acid synthase (CpFAS1) gene from Cryptosporidium parvum. , 2004, Molecular and biochemical parasitology.
[12] Christopher J. Tonkin,et al. Tropical infectious diseases: Metabolic maps and functions of the Plasmodium falciparum apicoplast , 2004, Nature Reviews Microbiology.
[13] J. Schachtner,et al. Apicomplexan parasites contain a single lipoic acid synthase located in the plastid , 2003, FEBS letters.
[14] Catherine Li,et al. High-Throughput Growth Assay for Toxoplasma gondii Using Yellow Fluorescent Protein , 2003, Antimicrobial Agents and Chemotherapy.
[15] S. Ralph,et al. A Type II Pathway for Fatty Acid Biosynthesis Presents Drug Targets in Plasmodium falciparum , 2003, Antimicrobial Agents and Chemotherapy.
[16] D. Soldati,et al. Role of Toxoplasma gondii Myosin A in Powering Parasite Gliding and Host Cell Invasion , 2002, Science.
[17] L. Sibley,et al. Host cells: mobilizable lipid resources for the intracellular parasite Toxoplasma gondii. , 2002, Journal of cell science.
[18] J. Logsdon,et al. Genetic complementation in apicomplexan parasites , 2002, Proceedings of the National Academy of Sciences of the United States of America.
[19] H. Bujard,et al. Modulation of myosin A expression by a newly established tetracycline repressor-based inducible system in Toxoplasma gondii. , 2001, Nucleic acids research.
[20] R J Heath,et al. Lipid biosynthesis as a target for antibacterial agents. , 2001, Progress in lipid research.
[21] D. Roos,et al. Targeting of soluble proteins to the rhoptries and micronemes in Toxoplasma gondii. , 2001, Molecular and biochemical parasitology.
[22] R. Lyons,et al. Triclosan inhibits the growth of Plasmodium falciparum and Toxoplasma gondii by inhibition of apicomplexan Fab I. , 2001, International journal for parasitology.
[23] D. Roos,et al. A plastid segregation defect in the protozoan parasite Toxoplasma gondii , 2001, The EMBO journal.
[24] N. Surolia,et al. Triclosan offers protection against blood stages of malaria by inhibiting enoyl-ACP reductase of Plasmodium falciparum , 2001, Nature Medicine.
[25] D. Roos,et al. The Plastid of Toxoplasma gondii Is Divided by Association with the Centrosomes , 2000, The Journal of cell biology.
[26] M. Parsons,et al. Analysis of targeting sequences demonstrates that trafficking to the Toxoplasma gondii plastid branches off the secretory system. , 2000, Journal of cell science.
[27] Yikun He,et al. Deficiency in Fatty Acid Synthase Leads to Premature Cell Death and Dramatic Alterations in Plant Morphology , 2000, Plant Cell.
[28] M. Jaquinod,et al. Fatty Acid and Lipoic Acid Biosynthesis in Higher Plant Mitochondria* , 2000, The Journal of Biological Chemistry.
[29] D. Roos,et al. Apicomplexan plastids as drug targets. , 1999, Trends in microbiology.
[30] R. Coppel,et al. Monoclonal antibodies to mitochondrial E2 components define autoepitopes in primary biliary cirrhosis. , 1998, Journal of immunology.
[31] D. Roos,et al. Nuclear-encoded proteins target to the plastid in Toxoplasma gondii and Plasmodium falciparum. , 1998, Proceedings of the National Academy of Sciences of the United States of America.
[32] Hsou-min Li,et al. A mutant deficient in the plastid lipid DGD is defective in protein import into chloroplasts. , 1998, The Plant journal : for cell and molecular biology.
[33] David S. Roos,et al. A plastid organelle as a drug target in apicomplexan parasites , 1997, Nature.
[34] J. Palmer,et al. A Plastid of Probable Green Algal Origin in Apicomplexan Parasites , 1997, Science.
[35] Geoffrey I. McFadden,et al. Plastid in human parasites , 1996, Nature.
[36] C. Hunter,et al. Cytokine mRNA in the central nervous system of SCID mice infected with Toxoplasma gondii: importance of T-cell-independent regulation of resistance to T. gondii , 1993, Infection and immunity.
[37] C. Rock,et al. Regulation of fatty acid biosynthesis in Escherichia coli. , 1993, Microbiological reviews.
[38] T. Roche,et al. Critical role of a lipoyl cofactor of the dihydrolipoyl acetyltransferase in the binding and enhanced function of the pyruvate dehydrogenase kinase. , 1993, Biochemical and biophysical research communications.
[39] G. Högenauer,et al. envM genes of Salmonella typhimurium and Escherichia coli , 1989, Journal of bacteriology.
[40] R. Schreiber,et al. Interferon-gamma: the major mediator of resistance against Toxoplasma gondii. , 1988, Science.
[41] S. Ōmura. The antibiotic cerulenin, a novel tool for biochemistry as an inhibitor of fatty acid synthesis. , 1976, Bacteriological reviews.
[42] E. Pfefferkorn,et al. Toxoplasma gondii: isolation and preliminary characterization of temperature-sensitive mutants. , 1976, Experimental parasitology.
[43] A. Fosbrooke,et al. A modified method for the preparation of methyl esters of a mixture of medium-chain and long-chain fatty acids. Application to the determination of serum triglyceride and non-esterified fatty acid composition and concentration by gas-liquid chromatography. , 1968, Clinica chimica acta; international journal of clinical chemistry.
[44] J. Folch,et al. A simple method for the isolation and purification of total lipides from animal tissues. , 1957, The Journal of biological chemistry.