Variation of force amplitude and its effects on local fatigue

Trends in industry are leaning toward stereotyped jobs with low workloads. Physical variation is an intervention to reduce fatigue and potentially musculoskeletal disorders in such jobs. Controlled laboratory studies have provided some insight into the effectiveness of physical variation, but very few have been devoted to force variation without muscular rest as a component. This study was undertaken to determine multiple physiological responses to five isometric elbow extension protocols with the same mean amplitude (15 % maximum voluntary contraction, MVC), cycle time (6 s), and duty cycle (50 %). Sustained (15 %Sus) and intermittent contractions including zero force (0–30 %Int) differed significantly in 19 of 27 response variables. Contractions varying by half the mean force (7.5–22.5 %Int) led to 8 and 7 measured responses that were significantly different from 0–30 %Int and 15 %Sus, respectively. A sinusoidal condition (0–30 %Sine) resulted in 2 variables that were significantly different from 0–30 %Int, and 16 different from 15 %Sus. Finally, ten response variables suggested that varying forces with 1 % as the lower contraction level was significantly less fatiguing than 15 %Sus, while no responses were significantly different from 0–30 %Int. Sustained contractions led to decreased twitch force 24-h post-exercise, whereas recovery was complete within 60 min after intermittent contractions. This suggests that time-varying force may be a useful intervention to reduce local fatigue in workers performing low-load tasks, and also that rest per se did not seem to cause any extraordinary effects beyond those predictable from the force variation amplitude.

[1]  Svend Erik Mathiassen,et al.  Changes in physical workload with implementation of mouse-based information technology in air traffic control , 2006 .

[2]  G. Hagg,et al.  Static work loads and occupational myalgia a new explanation model , 1991 .

[3]  Benjamin C Amick,et al.  Effect of Office Ergonomics Intervention on Reducing Musculoskeletal Symptoms , 2003, Spine.

[4]  J. Winkel,et al.  Occupational and individual risk factors for shoulder-neck complaints: Part II — The scientific basis (literature review) for the guide , 1992 .

[5]  H. Westerblad,et al.  High temperature does not alter fatigability in intact mouse skeletal muscle fibres , 2009, The Journal of physiology.

[6]  G. Borg,et al.  Exercise performance and perceived exertion in patients with coronary insufficiency, arterial hypertension and vasoregulatory asthenia. , 2009, Acta medica Scandinavica.

[7]  Jean-Luc Anton,et al.  Awareness of muscular force during movement production: an fMRI study , 2004, NeuroImage.

[8]  Richard P Wells,et al.  The effects of job rotation on the risk of reporting low back pain , 2003, Ergonomics.

[9]  Kurt Jørgensen,et al.  Electromyography and fatigue during prolonged, low-level static contractions , 2004, European Journal of Applied Physiology and Occupational Physiology.

[10]  R. Fitts,et al.  The cross-bridge cycle and skeletal muscle fatigue. , 2008, Journal of applied physiology.

[11]  J Winkel,et al.  Can occupational guidelines for work-rest schedules be based on endurance time data? , 1992, Ergonomics.

[12]  M. Nussbaum,et al.  Muscle fatigue and endurance during repetitive intermittent static efforts: development of prediction models , 2006, Ergonomics.

[13]  D. Warburton,et al.  Muscle deoxygenation of upper-limb muscles during progressive arm-cranking exercise. , 2008, Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme.

[14]  M A Nussbaum,et al.  Fatigue and endurance limits during intermittent overhead work. , 2001, AIHAJ : a journal for the science of occupational and environmental health and safety.

[15]  Mikael Forsman,et al.  Low-threshold motor unit activity during a 1-h static contraction in the trapezius muscle , 2002 .

[16]  Blossom Yen-Ju Lin,et al.  The Influence of Job Characteristics on Job Outcomes of Pharmacists in Hospital, Clinic, and Community Pharmacies , 2007, Journal of Medical Systems.

[17]  R Kadefors,et al.  EMG mean power frequency: Obtaining a reference value. , 1994, Clinical biomechanics.

[18]  F. Lötters,et al.  Are changes in mechanical exposure and musculoskeletal health good performance indicators for primary interventions? , 2002, International archives of occupational and environmental health.

[19]  Roger M Enoka,et al.  Accessory muscle activity contributes to the variation in time to task failure for different arm postures and loads. , 2007, Journal of applied physiology.

[20]  Bert R. Meijboom,et al.  Review and Evaluation , 1987 .

[21]  E. Chin,et al.  The role of elevations in intracellular [Ca2+] in the development of low frequency fatigue in mouse single muscle fibres. , 1996, The Journal of physiology.

[22]  A. R. Tupling The sarcoplasmic reticulum in muscle fatigue and disease: role of the sarco(endo)plasmic reticulum Ca2+-ATPase. , 2004, Canadian journal of applied physiology = Revue canadienne de physiologie appliquee.

[23]  Svend Erik Mathiassen,et al.  Efficient one-day sampling of mechanical job exposure data--a study based on upper trapezius activity in cleaners and office workers. , 2003, AIHA journal : a journal for the science of occupational and environmental health and safety.

[24]  Richard Wells,et al.  Effect of cycle time and duty cycle on psychophysically determined acceptable levels in a highly repetitive task , 2005, Ergonomics.

[25]  S H Snook,et al.  Perceived exertion and discomfort associated with driving screws at various work locations and at different work frequencies. , 1993, Ergonomics.

[26]  G. I. Zahalak,et al.  Myoelectric response of the human triceps brachii to displacement-controlled oscillations of the forearm , 2004, Experimental Brain Research.

[27]  Daniel Imbeau,et al.  Percentile values for determining maximum endurance times for static muscular work , 2006 .

[28]  K. Ebersole,et al.  Mechanomyographic and electromyographic responses to repeated concentric muscle actions of the quadriceps femoris. , 2006, Journal of electromyography and kinesiology : official journal of the International Society of Electrophysiological Kinesiology.

[29]  M W Weiner,et al.  Slow force recovery after long-duration exercise: metabolic and activation factors in muscle fatigue. , 1993, Journal of applied physiology.

[30]  B. Bigland-ritchie,et al.  Fatigue of intermittent submaximal voluntary contractions: central and peripheral factors. , 1986, Journal of applied physiology.

[31]  L. Forcier,et al.  Work related musculoskeletal disorders (WMSDs) : a reference book for prevention , 1995 .

[32]  R. Wells,et al.  The time variation pattern of mechanical exposure and the reporting of low back pain , 2008 .

[33]  Roger M Enoka,et al.  Net excitation of the motor unit pool varies with load type during fatiguing contractions , 2005, Muscle & nerve.

[34]  A Mital,et al.  Physical Fatigue in High and Very High Frequency Manual Materials Handling: Perceived Exertion and Physiological Indicators , 1994, Human factors.

[35]  Raymond W. McGorry,et al.  Oxygenation kinetics of forearm muscles as a function of handle diameter during a repetitive power grip force task , 2009 .

[36]  J. Potvin Effects of muscle kinematics on surface EMG amplitude and frequency during fatiguing dynamic contractions. , 1997, Journal of applied physiology.

[37]  K. Pyke,et al.  Rapid vasoregulatory mechanisms in exercising human skeletal muscle: dynamic response to repeated changes in contraction intensity. , 2006, American journal of physiology. Heart and circulatory physiology.

[38]  J Moxham,et al.  Changes in EMG power spectrum (high-to-low ratio) with force fatigue in humans. , 1982, Journal of applied physiology: respiratory, environmental and exercise physiology.

[39]  C. Rice,et al.  Perceived exertion is elevated in old age during an isometric fatigue task , 2003, European Journal of Applied Physiology.

[40]  Å. Kilbom,et al.  Physiological response in the forearm during and after isometric intermittent handgrip , 1991, European Journal of Applied Physiology and Occupational Physiology.

[41]  A. R. Lind,et al.  Sympathetic control of the forearm blood flow in man during brief isometric contractions , 2006, European Journal of Applied Physiology and Occupational Physiology.

[42]  K. Hansen,et al.  Trapezius muscle load as a risk indicator for occupational shoulder-neck complaints , 1993, International archives of occupational and environmental health.

[43]  C. Gielen,et al.  The relative activation of elbow-flexor muscles in isometric flexion and in flexion/extension movements. , 1997, Journal of biomechanics.

[44]  P. Dolan,et al.  Fatigue of the Erector Spinae Muscles: A Quantitative Assessment Using “Frequency Banding” of the Surface Electromyography Signal , 1995, Spine.

[45]  M. Hagberg,et al.  The effects of different pause types on neck and shoulder EMG activity during VDU work. , 1989, Ergonomics.

[46]  Kai Way Li,et al.  Ergonomic design and evaluation of wire-tying hand tools , 2002 .

[47]  M Hagberg,et al.  Muscular endurance and surface electromyogram in isometric and dynamic exercise. , 1981, Journal of applied physiology: respiratory, environmental and exercise physiology.

[48]  Anna Jaskólska,et al.  EMG and MMG activities of agonist and antagonist muscles in Parkinson's disease patients during absolute submaximal load holding. , 2009, Journal of electromyography and kinesiology : official journal of the International Society of Electrophysiological Kinesiology.

[49]  J. Fridén,et al.  Wrist Extensor Muscle Pathology in Lateral Epicondylitis , 1999, Journal of hand surgery.

[50]  G. Hägg Human muscle fibre abnormalities related to occupational load , 2000, European Journal of Applied Physiology.

[51]  Daniel Imbeau,et al.  Comparison of rest allowance models for static muscular work , 2009 .

[52]  T. Läubli,et al.  Continuous, intermitted and sporadic motor unit activity in the trapezius muscle during prolonged computer work. , 2003, Journal of electromyography and kinesiology : official journal of the International Society of Electrophysiological Kinesiology.

[53]  T. W. Van Weerden,et al.  Relationship between average muscle fibre conduction velocity and EMG power spectra during isometric contraction, recovery and applied ischemia , 2004, European Journal of Applied Physiology and Occupational Physiology.

[54]  Arend W A Van Gemmert,et al.  Forearm EMG response activity during motor performance in individuals prone to increased stress reactivity. , 2002, American journal of industrial medicine.

[55]  Bente Schibye,et al.  Shoulder muscle load and muscle fatigue among industrial sewing-machine operators , 2004, European Journal of Applied Physiology and Occupational Physiology.

[56]  Low-frequency fatigue, post-tetanic potentiation and their interaction at different muscle lengths following eccentric exercise , 2005, Journal of Experimental Biology.

[57]  B. Bigland-ritchie,et al.  Conduction velocity and EMG power spectrum changes in fatigue of sustained maximal efforts. , 1981, Journal of applied physiology: respiratory, environmental and exercise physiology.

[58]  T. Moritani,et al.  Assessment of lower-back muscle fatigue using electromyography, mechanomyography, and near-infrared spectroscopy , 2001, European Journal of Applied Physiology.

[59]  G Sjøgaard,et al.  Intramuscular pressure, EMG and blood flow during low-level prolonged static contraction in man. , 1986, Acta physiologica Scandinavica.

[60]  A. Spaepen,et al.  Muscle fatigue of the elbow flexor muscles during two intermittent exercise protocols with equal mean muscle loading. , 2004, Clinical biomechanics.

[61]  Allison Stephens,et al.  Maximal acceptable forces for manual insertions using a pulp pinch, oblique grasp and finger press , 2006 .

[62]  D G Stuart,et al.  Neurobiology of muscle fatigue. , 1992, Journal of applied physiology.

[63]  G. Sjøgaard,et al.  Assessment of postexercise muscle soreness by electromyography and mechanomyography. , 2002, The journal of pain : official journal of the American Pain Society.

[64]  Jack P. Callaghan,et al.  The role of load magnitude as a modifier of the cumulative load tolerance of porcine cervical spinal units: progress towards a force weighting approach , 2007 .

[65]  Roger Bartlett,et al.  Is movement variability important for sports biomechanists? , 2007, Sports biomechanics.

[66]  M. Bilodeau Central fatigue in continuous and intermittent contractions of triceps brachii , 2006, Muscle & nerve.

[67]  R. Westgaard Measurement and evaluation of postural load in occupational work situations , 2004, European Journal of Applied Physiology and Occupational Physiology.

[68]  Karen Søgaard,et al.  The effect of physical and psychosocial loads on the trapezius muscle activity during computer keying tasks and rest periods , 2004, European Journal of Applied Physiology.

[69]  Svend Erik Mathiassen,et al.  Job enlargement and mechanical exposure variability in cyclic assembly work , 2004, Ergonomics.

[70]  A. K. Blangsted,et al.  Interstitial muscle lactate, pyruvate and potassium dynamics in the trapezius muscle during repetitive low-force arm movements, measured with microdialysis. , 2004, Acta physiologica Scandinavica.

[71]  D. Pincivero,et al.  Gender differences in perceived exertion during fatiguing knee extensions. , 2004, Medicine and science in sports and exercise.

[72]  T J Housh,et al.  Mean power frequency and amplitude of the mechanomyographic and electromyographic signals during incremental cycle ergometry. , 2001, Journal of electromyography and kinesiology : official journal of the International Society of Electrophysiological Kinesiology.

[73]  D. Sale Postactivation potentiation: role in performance , 2004, British Journal of Sports Medicine.

[74]  Thomas M Hemmerling,et al.  Comparison of phonomyography, kinemyography and mechanomyography for neuromuscular monitoring , 2006, Canadian journal of anaesthesia = Journal canadien d'anesthesie.

[75]  N. Vøllestad,et al.  Motor Unit Recruitment , 1987 .

[76]  J. Kuk,et al.  Do vasoregulatory mechanisms in exercising human muscle compensate for changes in arterial perfusion pressure? , 2007, American journal of physiology. Heart and circulatory physiology.

[77]  R H Westgaard,et al.  Pattern of muscle activity during stereotyped work and its relation to muscle pain , 1990, International archives of occupational and environmental health.

[78]  G M Hägg,et al.  Normalization of surface EMG amplitude from the upper trapezius muscle in ergonomic studies - A review. , 1995, Journal of electromyography and kinesiology : official journal of the International Society of Electrophysiological Kinesiology.

[79]  G. Allison,et al.  The relationship between EMG median frequency and low frequency band amplitude changes at different levels of muscle capacity. , 2002, Clinical biomechanics.

[80]  Annika Åström,et al.  Load pattern and pressure pain threshold in the upper trapezius muscle and psychosocial factors in medical secretaries with and without shoulder/neck disorders , 1997, International archives of occupational and environmental health.

[81]  Svend Erik Mathiassen,et al.  Time--a key issue for musculoskeletal health and manufacturing. , 2007, Applied ergonomics.

[82]  Shrawan Kumar,et al.  Work-Related Musculoskeletal Disorders: Design as a Prevention Strategy. A Review , 2001, Journal of Occupational Rehabilitation.

[83]  M. Mador,et al.  Comparison of potentiated and unpotentiated twitches as an index of muscle fatigue , 2002, Muscle & nerve.

[84]  C. Orizio,et al.  Surface mechanomyogram amplitude is not attenuated by intramuscular pressure , 2004, European Journal of Applied Physiology.

[85]  Roger M Enoka,et al.  Task differences with the same load torque alter the endurance time of submaximal fatiguing contractions in humans. , 2002, Journal of neurophysiology.

[86]  Roger M Enoka,et al.  Changes in muscle activation can prolong the endurance time of a submaximal isometric contraction in humans. , 2003, Journal of applied physiology.

[87]  A. Fuglevand,et al.  Re‐Evaluation of Muscle Wisdom in the Human Adductor Pollicis using Physiological Rates of Stimulation , 2003, The Journal of physiology.

[88]  Patrick Gaydecki,et al.  Within-day and between-days reliability of quadriceps isometric muscle fatigue using mechanomyography on healthy subjects. , 2009, Journal of electromyography and kinesiology : official journal of the International Society of Electrophysiological Kinesiology.

[89]  W Rohmert,et al.  Problems in determining rest allowances Part 1: use of modern methods to evaluate stress and strain in static muscular work. , 1973, Applied ergonomics.

[90]  H. A. Dahl,et al.  Effect of training with different intensities and volumes on muscle fibre enzyme activity and cross sectional area in the m. triceps brachii , 2008, European Journal of Applied Physiology.

[91]  M. A. Sandrey Effects of Acute and Chronic Pathomechanics on the Normal Histology and Biomechanics of Tendons: A Review , 2000 .

[92]  R. Larsson,et al.  Changes of trapezius muscle blood flow and electromyography in chronic neck pain due to trapezius myalgia , 1999, Pain.

[93]  Jack P Callaghan,et al.  Effects of prolonged sitting on the passive flexion stiffness of the in vivo lumbar spine. , 2005, The spine journal : official journal of the North American Spine Society.

[94]  J. Basmajian,et al.  Agonist and antagonist activity during voluntary upper-limb movement in patients with stroke. , 1992, Physical therapy.

[95]  P Asterland,et al.  Muscular rest and gap frequency as EMG measures of physical exposure: the impact of work tasks and individual related , 2000, Ergonomics.

[96]  Effects of activation frequency and force on low-frequency fatigue in human skeletal muscle. , 1999, Journal of applied physiology.

[97]  Bart Visser,et al.  Pathophysiology of upper extremity muscle disorders. , 2006, Journal of electromyography and kinesiology : official journal of the International Society of Electrophysiological Kinesiology.

[98]  D. Gravel,et al.  EMG power spectra of elbow extensors during ramp and step isometric contractions , 2004, European Journal of Applied Physiology and Occupational Physiology.

[99]  M. Nussbaum,et al.  Muscular load characterization during isometric shoulder abductions with varying force. , 2008, Journal of electromyography and kinesiology : official journal of the International Society of Electrophysiological Kinesiology.

[100]  A Naito,et al.  Electromyographic study of the elbow flexors and extensors in a motion of forearm pronation/supination while maintaining elbow flexion in humans. , 1998, The Tohoku journal of experimental medicine.

[101]  L. Griffin,et al.  Fatigue in high- versus low-force voluntary and evoked contractions , 2008, Experimental Brain Research.

[102]  T. Noakes,et al.  Linear relationship between the perception of effort and the duration of constant load exercise that remains. , 2004, Journal of applied physiology.

[103]  P. Clifford,et al.  Blood flow response to muscle contractions is more closely related to metabolic rate than contractile work. , 2005, Journal of applied physiology.

[104]  S. Mathiassen,et al.  Physiological effects of micropauses in isometric handgrip exercise , 2004, European Journal of Applied Physiology and Occupational Physiology.

[105]  R. Cutlip,et al.  Injury and adaptive mechanisms in skeletal muscle. , 2009, Journal of electromyography and kinesiology : official journal of the International Society of Electrophysiological Kinesiology.

[106]  K. Avin,et al.  Endurance time is joint-specific: A modelling and meta-analysis investigation , 2010, Ergonomics.

[107]  D. Allen,et al.  Changes of myoplasmic calcium concentration during fatigue in single mouse muscle fibers , 1991, The Journal of general physiology.

[108]  J Tanji,et al.  Recruitment of motor units in voluntary contraction of a finger muscle in man. , 1973, Experimental neurology.

[109]  Tao-Ming Cheng,et al.  A model used in creating a work-rest schedule for laborers , 2009 .

[110]  S H Snook,et al.  Psychophysical study of six hand movements , 2001, Ergonomics.

[111]  C. Orizio,et al.  The surface mechanomyogram as a tool to describe the influence of fatigue on biceps brachii motor unit activation strategy. Historical basis and novel evidence , 2003, European Journal of Applied Physiology.

[112]  Anne E. Moore,et al.  Effect of Cycle Time and Duty Cycle on Muscle Activity during a Repetitive Manual Task , 2000 .

[113]  J. Basmajian Muscles Alive—their functions revealed by electromyography , 1963 .

[114]  Marco Ferrari,et al.  Biceps brachii myoelectric and oxygenation changes during static and sinusoidal isometric exercises. , 2009, Journal of electromyography and kinesiology : official journal of the International Society of Electrophysiological Kinesiology.

[115]  R H Westgaard,et al.  Motor unit substitution in long-duration contractions of the human trapezius muscle. , 1999, Journal of neurophysiology.

[116]  H. Freund,et al.  The relationship between the rate of rise of isometric tension and motor unit recruitment in a human forearm muscle , 1976, Pflügers Archiv.

[117]  J R Potvin,et al.  A validation of techniques using surface EMG signals from dynamic contractions to quantify muscle fatigue during repetitive tasks. , 1997, Journal of electromyography and kinesiology : official journal of the International Society of Electrophysiological Kinesiology.

[118]  Y. Bhambhani,et al.  A Brief Review of the Use of Near Infrared Spectroscopy with Particular Interest in Resistance Exercise , 2007, Sports medicine.

[119]  Allard J. van der Beek,et al.  Effect of Job Rotation on Work Demands, Workload, and Recovery of Refuse Truck Drivers and Collectors , 2004, Hum. Factors.

[120]  W Rohmert,et al.  Problems of determination of rest allowances Part 2: determining rest allowances in different human tasks. , 1973, Applied ergonomics.

[121]  L. Griffin,et al.  Blood flow in the triceps brachii muscle in humans during sustained submaximal isometric contractions , 2001, European Journal of Applied Physiology.

[122]  K. Jørgensen,et al.  Modification of myo-electric power spectrum in fatigue from 15% maximal voluntary contraction of human elbow flexor muscles, to limit of endurance: reflection of conduction velocity variation and/or centrally mediated mechanisms? , 2004, European Journal of Applied Physiology and Occupational Physiology.

[123]  S. Konz Work/rest: Part II – The scientific basis (knowledge base) for the guide1 , 2000 .

[124]  P Madeleine,et al.  On functional motor adaptations: from the quantification of motor strategies to the prevention of musculoskeletal disorders in the neck–shoulder region , 2010, Acta physiologica.

[125]  Dario Farina,et al.  Periodic increases in force during sustained contraction reduce fatigue and facilitate spatial redistribution of trapezius muscle activity , 2007, Experimental Brain Research.

[126]  Dario Farina,et al.  Cross-comparison of time- and frequency-domain methods for monitoring the myoelectric signal during a cyclic, force-varying, fatiguing hand-grip task. , 2005, Journal of electromyography and kinesiology : official journal of the International Society of Electrophysiological Kinesiology.

[127]  T. Eriksson,et al.  The Adoption of Job Rotation: Testing the Theories , 2006 .

[128]  R. Hughson,et al.  Dependence of muscle VO2 on blood flow dynamics at onset of forearm exercise. , 1996, Journal of applied physiology.

[129]  V. Valencic,et al.  Evaluation of the ability to make non-invasive estimation of muscle contractile properties on the basis of the muscle belly response , 2006, Medical and Biological Engineering and Computing.

[130]  Tim Bosch,et al.  Manifestations of shoulder fatigue in prolonged activities involving low-force contractions , 2009, Ergonomics.

[131]  Exercise proves effective in a systematic review of work-related complaints of the arm, neck, or shoulder. , 2007, Journal of clinical epidemiology.

[132]  T. F. Reardon,et al.  Time to fatigue is increased in mouse muscle at 37°C; the role of iron and reactive oxygen species , 2009, The Journal of physiology.

[133]  LW O'Sullivan,et al.  Forearm torque strengths and discomfort profiles in pronation and supination , 2005, Ergonomics.

[134]  Mahmut Eksioglu,et al.  Optimal work–rest cycles for an isometric intermittent gripping task as a function of force, posture and grip span , 2006, Ergonomics.

[135]  J. Frank,et al.  Twitch potentiation after fatiguing exercise in man , 2004, European Journal of Applied Physiology and Occupational Physiology.

[136]  Hongming Cai,et al.  Effects of psychophysiological stress on trapezius muscles blood flow and electromyography during static load , 2004, European Journal of Applied Physiology and Occupational Physiology.

[137]  G. Hagg,et al.  Interpretation of EMG spectral alterations and alteration indexes at sustained contraction. , 1992 .

[138]  L. Zhang,et al.  Moment distribution among human elbow extensor muscles during isometric and submaximal extension. , 2000, Journal of biomechanics.

[139]  J Winkel,et al.  Guidelines for occupational musculoskeletal load as a basis for intervention: a critical review. , 1996, Applied ergonomics.

[140]  L. Lindberg,et al.  Muscle blood flow in response to concentric muscular activity vs passive venous compression. , 2004, Acta physiologica Scandinavica.

[141]  B Jonsson,et al.  Endurance limit of force in long-term intermittent static contractions. , 1977, Scandinavian journal of work, environment & health.

[142]  Elisabeth Fernström,et al.  Alterations in shoulder muscle activity due to changes in data entry organisation , 1999 .

[143]  Michael J. Mueller,et al.  Tissue adaptation to physical stress: a proposed "Physical Stress Theory" to guide physical therapist practice, education, and research. , 2002, Physical therapy.

[144]  R M Enoka,et al.  Mechanisms of muscle fatigue: Central factors and task dependency. , 1995, Journal of electromyography and kinesiology : official journal of the International Society of Electrophysiological Kinesiology.

[145]  R. Enoka,et al.  Activation among the elbow flexor muscles differs when maintaining arm position during a fatiguing contraction. , 2003, Journal of applied physiology.

[146]  C Fransson-Hall,et al.  Acceptability of Intermittent Handgrip Contractions Based on Physiological Response , 1994, Human factors.

[147]  K Jørgensen,et al.  Blood pressure, heart rate and EMG in low level static contractions. , 1985, Acta physiologica Scandinavica.

[148]  Minoru Shinohara,et al.  Mechanomyography for Studying Force Fluctuations and Muscle Fatigue , 2006, Exercise and sport sciences reviews.

[149]  David A. Winter,et al.  Biomechanics and Motor Control of Human Movement , 1990 .

[150]  Maury A Nussbaum,et al.  Utility of traditional and alternative EMG-based measures of fatigue during low-moderate level isometric efforts. , 2008, Journal of electromyography and kinesiology : official journal of the International Society of Electrophysiological Kinesiology.

[151]  J. D. Mis,et al.  Effects of a stress field on boron ion implantation damage in silicon , 1993 .

[152]  L. Wolf,et al.  Reduction in injury rates in nursing personnel through introduction of mechanical lifts in the workplace. , 2003, American journal of industrial medicine.

[153]  C. J. Luca,et al.  Motor unit recruitment and derecruitment induced by brief increase in contraction amplitude of the human trapezius muscle , 2003, The Journal of physiology.

[154]  Svend Erik Mathiassen,et al.  Prediction of shoulder flexion endurance from personal factors , 1999 .

[155]  D. Rempel,et al.  Workplace interventions to prevent musculoskeletal and visual symptoms and disorders among computer users: A systematic review , 2006, Journal of Occupational Rehabilitation.

[156]  B J Martin,et al.  Please Scroll down for Article Ergonomics Low Mean Level Sustained and Intermittent Grip Exertions: Influence of Age on Fatigue and Recovery Low Mean Level Sustained and Intermittent Grip Exertions: Influence of Age on Fatigue and Recovery , 2022 .

[157]  Bengt Jonsson,et al.  The static load component in muscle work , 2004, European Journal of Applied Physiology and Occupational Physiology.

[158]  N. Vøllestad,et al.  Mechanical behavior of skeletal muscle during intermittent voluntary isometric contractions in humans. , 1997, Journal of applied physiology.

[159]  S H Snook,et al.  Psychophysical studies of repetitive wrist flexion and extension. , 1995, Ergonomics.

[160]  J. Olesen,et al.  In vivo evidence of altered skeletal muscle blood flow in chronic tension-type headache. , 2002, Brain : a journal of neurology.

[161]  P Cordo,et al.  Proprioceptive coordination of movement sequences: role of velocity and position information. , 1994, Journal of neurophysiology.

[162]  Heecheon You,et al.  A survey of repetitiveness assessment methodologies for hand-intensive tasks , 2005 .

[163]  Claudio Orizio,et al.  Muscle tissue oxygenation, pressure, electrical, and mechanical responses during dynamic and static voluntary contractions , 2004, European Journal of Applied Physiology.

[164]  S N MacKinnon,et al.  Relating heart rate and rate of perceived exertion in two simulated occupational tasks. , 1999, Ergonomics.

[165]  Bente R Jensen,et al.  Physiological responses to four hours of low-level repetitive work. , 2003, Scandinavian journal of work, environment & health.

[166]  Maury A Nussbaum,et al.  Fatigue during prolonged intermittent overhead work: reliability of measures and effects of working height , 2007, Ergonomics.

[167]  P Madeleine,et al.  Mechanomyography and electromyography during and after fatiguing shoulder eccentric contractions in males and females , 2006, Scandinavian journal of medicine & science in sports.

[168]  S. McGill The biomechanics of low back injury: implications on current practice in industry and the clinic. , 1997, Journal of biomechanics.

[169]  P Madeleine,et al.  Evidence of long term muscle fatigue following prolonged intermittent contractions based on mechano- and electromyograms. , 2003, Journal of electromyography and kinesiology : official journal of the International Society of Electrophysiological Kinesiology.

[170]  A. Mannion,et al.  Muscle fibre size and type distribution in thoracic and lumbar regions of erector spinae in healthy subjects without low back pain: normal values and sex differences , 1997, Journal of anatomy.

[171]  K. Pyke,et al.  Dynamic response characteristics of local muscle blood flow regulatory mechanisms in human forearm exercise. , 2005, Journal of applied physiology.

[172]  Svend Erik Mathiassen,et al.  Increased physical work loads in modern work – a necessity for better health and performance? , 2009, Ergonomics.

[173]  Åsa Kilbom,et al.  Physiological response in the forearm during and after isometric intermittent handgrip , 1991 .

[174]  Jane A. Kent-Braun,et al.  Central and peripheral contributions to muscle fatigue in humans during sustained maximal effort , 1999, European Journal of Applied Physiology and Occupational Physiology.

[175]  P A Merton,et al.  Fatigue of long duration in human skeletal muscle after exercise. , 1977, The Journal of physiology.

[176]  T. Moritani,et al.  Selective fatigue of fast motor units after electrically elicited muscle contractions. , 2004, Journal of electromyography and kinesiology : official journal of the International Society of Electrophysiological Kinesiology.

[177]  N. Thompson,et al.  Review and evaluation , 1996 .

[178]  David Bonauto,et al.  Rotator Cuff Syndrome: Personal, Work-Related Psychosocial and Physical Load Factors , 2008, Journal of occupational and environmental medicine.

[179]  Theodore F. Towse,et al.  Human skeletal muscle responses vary with age and gender during fatigue due to incremental isometric exercise. , 2002, Journal of applied physiology.

[180]  Philippe Gorce,et al.  Upper limb muscle forces during a simple reach-to-grasp movement: a comparative study , 2009, Medical & Biological Engineering & Computing.

[181]  K Iwanaga,et al.  Endurance time and fatigue in static contractions. , 1984, Journal of human ergology.

[182]  Karen Søgaard,et al.  Work Design and the Labouring Body: Examining the Impacts of Work Organization on Danish Cleaners’ Health , 2006 .

[183]  Kermit Davis,et al.  Characteristics of job rotation in the Midwest US manufacturing sector , 2005, Ergonomics.

[184]  A. de Haan,et al.  Sex differences in contractile properties and fatigue resistance of human skeletal muscle , 2008, Experimental physiology.

[185]  M. Price,et al.  The effects of work:rest duration on physiological and perceptual responses during intermittent exercise and performance , 2007, Journal of sports sciences.

[186]  Ramaratnam R Bishu,et al.  Review and evaluation of techniques for determining fatigue allowances , 1991 .

[187]  G. Sjøgaard,et al.  Development of muscle fatigue as assessed by electromyography and mechanomyography during continuous and intermittent low-force contractions: effects of the feedback mode , 2002, European Journal of Applied Physiology.

[188]  Å. Kilbom,et al.  Repetitive work of the upper extremity: Part I—Guidelines for the practitioner , 1994 .

[189]  Joseph P. Weir,et al.  Mechanomyographic and electromyographic responses during fatigue in humans: influence of muscle length , 2000, European Journal of Applied Physiology.

[190]  R. Westgaard,et al.  Electromyographic evaluation of muscular work pattern as a predictor of trapezius myalgia. , 1993, Scandinavian journal of work, environment & health.

[191]  T J Armstrong,et al.  Hand wrist cumulative trauma disorders in industry. , 1986, British journal of industrial medicine.

[192]  L. Thornell,et al.  Fiber type composition of the human female trapezius muscle: enzyme-histochemical characteristics. , 1991, The American journal of anatomy.

[193]  Troy V. Mumford,et al.  Work redesign: Eight obstacles and opportunities , 2005 .

[194]  Effects of 30 versus 60 min of low-load work on intramuscular lactate, pyruvate, glutamate, prostaglandin E2 and oxygenation in the trapezius muscle of healthy females , 2006, European Journal of Applied Physiology.

[195]  J. Marusiak,et al.  Similar response of agonist and antagonist muscles after eccentric exercise revealed by electromyography and mechanomyography. , 2007, Journal of electromyography and kinesiology : official journal of the International Society of Electrophysiological Kinesiology.

[196]  Stephan Konz,et al.  Work/rest: Part II The scientific basis (knowledge base) for the guide 1 The recommendations provi , 1998 .

[197]  Richard Wells,et al.  Characterizing the intensity of changes made to reduce mechanical exposure. , 2009, Work.

[198]  Roland Kadefors,et al.  Motor-unit recruitment in the trapezius muscle during arm movements and in VDU precision work , 1999 .

[199]  R. L. Linscheid,et al.  Muscles across the elbow joint: a biomechanical analysis. , 1981, Journal of biomechanics.

[200]  M. A. Frens,et al.  Differences in muscle load between computer and non-computer work among office workers , 2009, Ergonomics.

[201]  Pascal Madeleine,et al.  Voluntary low-force contraction elicits prolonged low-frequency fatigue and changes in surface electromyography and mechanomyography. , 2005, Journal of electromyography and kinesiology : official journal of the International Society of Electrophysiological Kinesiology.

[202]  Alwin Luttmann,et al.  Electromyographical indication of muscular fatigue in occupational field studies , 2000 .

[203]  L. R. Altimari,et al.  The relationship between rating of perceived exertion and muscle activity during exhaustive constant-load cycling. , 2010, International journal of sports medicine.

[204]  J. Taylor,et al.  Autonomic mediation of the pressor responses to isometric exercise in humans. , 1988, Journal of applied physiology.

[205]  Dianne A. C. M. Commissaris,et al.  Recommendations for sufficient physical activity at work : promoting physical activity in low intensity static jobs , 2006 .

[206]  Richard Wells,et al.  Mechanical exposure concepts using force as the agent. , 2004, Scandinavian journal of work, environment & health.

[207]  M. Pozzo,et al.  Relationship between perceived exertion and mean power frequency of the EMG signal from the upper trapezius muscle during isometric shoulder elevation , 2005, European Journal of Applied Physiology.

[208]  Svend Erik Mathiassen,et al.  Diversity and variation in biomechanical exposure: what is it, and why would we like to know? , 2006, Applied ergonomics.

[209]  E. Hultman,et al.  ATP utilization and force during intermittent and continuous muscle contractions. , 1987, Journal of applied physiology.

[210]  Timothy J. Gallwey,et al.  Upper limb discomfort profile due to intermittent isometric pronation torque at different postural combinations of the shoulder-arm system , 2009, Ergonomics.

[211]  E. Hultman,et al.  Glycogen degradation during isometric exercise at low contraction force , 2004, European Journal of Applied Physiology and Occupational Physiology.

[212]  A Kossev,et al.  Discharge pattern of human motor units during dynamic concentric and eccentric contractions. , 1998, Electroencephalography and clinical neurophysiology.

[213]  H. J. Coury,et al.  Evaluation of musculoskeletal health outcomes in the context of job rotation and multifunctional jobs. , 2009, Applied ergonomics.

[214]  MUSCLE BLOOD FLOW , 1962 .

[215]  G. Somjen,et al.  Excitability and inhibitability of motoneurons of different sizes. , 1965, Journal of neurophysiology.

[216]  N. Vøllestad Measurement of human muscle fatigue , 1997, Journal of Neuroscience Methods.

[217]  A Eriksson,et al.  Fiber type composition of the human male trapezius muscle: enzyme-histochemical characteristics. , 1990, The American journal of anatomy.

[218]  Svend Erik Mathiassen The influence of exercise/rest schedule on the physiological and psychophysical response to isometric shoulder-neck exercise , 2004, European Journal of Applied Physiology and Occupational Physiology.

[219]  N. Jones,et al.  Exercise limitation in health and disease. , 2000, The New England journal of medicine.

[220]  A. Burdorf,et al.  Workplace interventions , 2004, Occupational and Environmental Medicine.