Cloud enabled data analytics and visualization framework for health-shocks prediction

In this paper, we present a data analytics and visualization framework for health-shocks prediction based on large-scale health informatics dataset. The framework is developed using cloud computing services based on Amazon web services (AWS) integrated with geographical information systems (GIS) to facilitate big data capture, storage, index and visualization of data through smart devices for different stakeholders. In order to develop a predictive model for health-shocks, we have collected a unique data from 1000 households, in rural and remotely accessible regions of Pakistan, focusing on factors like health, social, economic, environment and accessibility to healthcare facilities. We have used the collected data to generate a predictive model of health-shock using a fuzzy rule summarization technique, which can provide stakeholders with interpretable linguistic rules to explain the causal factors affecting health-shocks. The evaluation of the proposed system in terms of the interpret-ability and accuracy of the generated data models for classifying health-shock shows promising results. The prediction accuracy of the fuzzy model based on a k-fold cross-validation of the data samples shows above 89% performance in predicting health-shocks based on the given factors. Cloud enabled framework for interactive data visualization, gathering, & analysis.Analysis of iron triangle under socioeconomic, cultural, and geographical norms.First publicly available data-set to understand health-shocks and its causes.

[1]  E. Bernad,et al.  Flexible Solution for Interoperable Cloud Healthcare Systems , 2012, MIE.

[2]  A. Fitzgibbons Uncertainty and Decisions , 2000 .

[3]  Nathan Regola,et al.  Storing and Using Health Data in a Virtual Private Cloud , 2013, Journal of medical Internet research.

[4]  John W. Creswell,et al.  Research Design: Qualitative, Quantitative, and Mixed Methods Approaches , 2010 .

[5]  Mark Schreiner,et al.  A Simple Poverty Scorecard for Pakistan , 2010 .

[6]  Adnan A Hyder,et al.  Non-communicable diseases and injuries in Pakistan: strategic priorities , 2013, The Lancet.

[7]  T. Murdoch,et al.  The inevitable application of big data to health care. , 2013, JAMA.

[8]  Peter Szolovits,et al.  Artificial intelligence in medical diagnosis. , 1988, Annals of internal medicine.

[9]  Han-Yu Lin,et al.  Secure PHR Access Control Scheme for Healthcare Application Clouds , 2013, 2013 42nd International Conference on Parallel Processing.

[10]  José Luís Oliveira,et al.  A PACS archive architecture supported on cloud services , 2012, International Journal of Computer Assisted Radiology and Surgery.

[11]  P. Gill,et al.  Methods of data collection in qualitative research: interviews and focus groups , 2008, BDJ.

[12]  Yan Bai,et al.  Design and Implementation of a Secure Healthcare Social Cloud System , 2012, 2012 12th IEEE/ACM International Symposium on Cluster, Cloud and Grid Computing (ccgrid 2012).

[13]  Robert LIN,et al.  NOTE ON FUZZY SETS , 2014 .

[14]  Graeme McFerren,et al.  Fuzzy expert systems and GIS for cholera health risk prediction in southern Africa , 2007, Environ. Model. Softw..

[15]  D. Eignor The standards for educational and psychological testing. , 2013 .

[16]  Arnon Rosenthal,et al.  Methodological Review: Cloud computing: A new business paradigm for biomedical information sharing , 2010 .

[17]  J. Piette,et al.  Hypertension management using mobile technology and home blood pressure monitoring: results of a randomized trial in two low/middle-income countries. , 2012, Telemedicine journal and e-health : the official journal of the American Telemedicine Association.

[18]  C-M Chiu,et al.  The dilemma of "to be or not to be": developing electronically e-health & cloud computing documents for overseas transplant patients from Taiwan organ transplant health professionals' perspective. , 2012, Transplantation proceedings.

[19]  J. Mattson Transportation, Distance, and Health Care Utilization for Older Adults in Rural and Small Urban Areas , 2011 .

[20]  Trevor Hastie,et al.  The Elements of Statistical Learning , 2001 .

[21]  Cristina Alcaraz,et al.  Wireless Sensor Networks and the Internet of Things: Do We Need a Complete Integration? , 2010, IWSEC 2010.

[22]  A. Kuo Opportunities and Challenges of Cloud Computing to Improve Health Care Services , 2011, Journal of medical Internet research.

[23]  Samaneh Sheikh-Nia,et al.  An Investigation of Standard and Ensemble Based Classification Techniques for the Prediction of Hospitalization Duration , 2012 .

[24]  M. Fieschi,et al.  Sharing knowledge in medicine: semantic and ontologic facets of medical concepts , 1999, IEEE SMC'99 Conference Proceedings. 1999 IEEE International Conference on Systems, Man, and Cybernetics (Cat. No.99CH37028).

[25]  Yi-Jun Chen,et al.  Cloud-Based Hospital Information System as a Service for Grassroots Healthcare Institutions , 2014, Journal of Medical Systems.

[26]  Hisao Ishibuchi,et al.  Rule weight specification in fuzzy rule-based classification systems , 2005, IEEE Transactions on Fuzzy Systems.

[27]  P. Shekelle,et al.  Systematic Review: Impact of Health Information Technology on Quality, Efficiency, and Costs of Medical Care , 2006, Annals of Internal Medicine.

[28]  Jennifer Urner Medicines Dilemmas Infinite Needs Versus Finite Resources , 2016 .

[29]  Paul G Nagy,et al.  Cloud computing in medical imaging. , 2013, Medical physics.

[30]  Rolf H. Weber,et al.  Accountability in the Internet of Things , 2011, Comput. Law Secur. Rev..

[31]  Zhanpeng Jin,et al.  Enabling Smart Personalized Healthcare: A Hybrid Mobile-Cloud Approach for ECG Telemonitoring , 2014, IEEE Journal of Biomedical and Health Informatics.

[32]  Jorge Werner,et al.  A Cloud Computing Solution for Patient's Data Collection in Health Care Institutions , 2010, 2010 Second International Conference on eHealth, Telemedicine, and Social Medicine.

[33]  Alan H. Karp,et al.  Fusion: Managing Healthcare Records at Cloud Scale , 2012, Computer.

[34]  Zhibo Pang,et al.  Intelligent packaging and intelligent medicine box for medication management towards the Internet-of-Things , 2014, 16th International Conference on Advanced Communication Technology.

[35]  Weiming Shen,et al.  A home mobile healthcare system for wheelchair users , 2014, Proceedings of the 2014 IEEE 18th International Conference on Computer Supported Cooperative Work in Design (CSCWD).

[36]  Wei Zhao,et al.  Medical application on Internet of Things , 2011 .

[37]  Swapnaja R. Hiray,et al.  Dental patient records maintenance on cloud computing using data protection model , 2012, CUBE.

[38]  Ajith Abraham,et al.  Hybrid Intelligent Systems Design - A Review of a Decade of Research , 2000 .

[39]  Fatos Xhafa,et al.  Implementation of a Medical Support System Considering P2P and IoT Technologies , 2014, 2014 Eighth International Conference on Complex, Intelligent and Software Intensive Systems.

[40]  Hiroyuki Yoshida,et al.  Scalable, high-performance 3D imaging software platform: System architecture and application to virtual colonoscopy , 2012, 2012 Annual International Conference of the IEEE Engineering in Medicine and Biology Society.

[41]  Gerhard Nussbaum People with Disabilities: Assistive Homes and Environments , 2006, ICCHP.

[42]  Raouf Boutaba,et al.  Cloud computing: state-of-the-art and research challenges , 2010, Journal of Internet Services and Applications.

[43]  Ning Zhang,et al.  An Open, Secure and Flexible Platform Based on Internet of Things and Cloud Computing for Ambient Aiding Living and Telemedicine , 2011, 2011 International Conference on Computer and Management (CAMAN).

[44]  Chris Elbers,et al.  Growth and Risk: Methodology and Micro Evidence , 2003 .

[45]  W. Mendoza,et al.  Gaps in policy-relevant information on burden of disease in children: a systematic review , 2005, The Lancet.

[46]  Heikki Mannila,et al.  Principles of Data Mining , 2001, Undergraduate Topics in Computer Science.

[47]  Abdul Hanan Abdullah,et al.  Smart Environment as a Service: Three Factor Cloud Based User Authentication for Telecare Medical Information System , 2013, Journal of Medical Systems.

[48]  Victor Chang,et al.  TEMPORARY REMOVAL: An overview, examples and impacts offered by Emerging Services and Analytics in Cloud Computing , 2015 .

[49]  Miguel López-Coronado,et al.  Analysis of the Security and Privacy Requirements of Cloud-Based Electronic Health Records Systems , 2013, Journal of medical Internet research.

[50]  Josip Car,et al.  mHealth series: New ideas for mHealth data collection implementation in low– and middle–income countries , 2013, Journal of global health.

[51]  Anne E. James,et al.  ARREST: From work practices to redesign for usability , 2011, Expert Syst. Appl..

[52]  Randy H. Katz,et al.  Above the Clouds: A Berkeley View of Cloud Computing , 2009 .

[53]  Martin Courtney Puzzling out big data [Information Technology Analytics] , 2013 .

[54]  Ralf Steinmetz,et al.  Wireless Sensor Networks and the Internet of Things: Selected Challenges , 2009 .

[55]  Pedro Castillejo,et al.  Integration of wearable devices in a wireless sensor network for an E-health application , 2013, IEEE Wireless Communications.

[56]  Muthu Ramachandran,et al.  Cloud Computing Adoption Framework – a security framework for business clouds , 2015 .

[57]  Ilias Maglogiannis,et al.  Bringing IoT and Cloud Computing towards Pervasive Healthcare , 2012, 2012 Sixth International Conference on Innovative Mobile and Internet Services in Ubiquitous Computing.

[58]  Benedict Tan,et al.  Short paper: Using BSN for tele-health application in upper limb rehabilitation , 2014, 2014 IEEE World Forum on Internet of Things (WF-IoT).

[59]  Zhibo Pang,et al.  Technologies and Architectures of the Internet-of-Things (IoT) for Health and Well-being , 2013 .

[60]  Ibrahim Khalil,et al.  Protection of electronic health records (EHRs) in cloud , 2013, 2013 35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC).

[61]  Marzyeh Ghassemi,et al.  Short-term Mortality Prediction for Elderly Patients Using Medicare Claims Data , 2015, International journal of machine learning and computing.

[62]  Alexandre Santos,et al.  Security architecture for mobile e-health applications in medication control , 2013, 2013 21st International Conference on Software, Telecommunications and Computer Networks - (SoftCOM 2013).

[63]  Miao Liu,et al.  Against conventional wisdom: when the public, the media, and medical practice collide , 2013, BMC Medical Informatics and Decision Making.

[64]  Benjamin Fabian,et al.  Secret Sharing for Health Data in Multi-provider Clouds , 2013, 2013 IEEE 15th Conference on Business Informatics.

[65]  Reihaneh Safavi-Naini,et al.  Privacy preserving EHR system using attribute-based infrastructure , 2010, CCSW '10.

[66]  Chunming Gao,et al.  CloudHealth: Developing a reliable cloud platform for healthcare applications , 2013, 2013 IEEE 10th Consumer Communications and Networking Conference (CCNC).

[67]  J. Bustamante,et al.  A mobile application for ambulatory electrocardiographic monitoring in clinical and domestic environments , 2013, 2013 Pan American Health Care Exchanges (PAHCE).

[68]  Thurasamy Ramayah,et al.  A Structural Equation Modeling Approach for the Adoption of Cloud Computing to Enhance the Malaysian Healthcare Sector , 2014, Journal of Medical Systems.

[69]  Sang-Joong Jung,et al.  A wireless sensor network compatible wearable u-healthcare monitoring system using integrated ECG, accelerometer and SpO2. , 2008, Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference.

[70]  Wei Li,et al.  An Immune Theory Based Health Monitoring and Risk Evaluation of Earthen Sites with Internet of Things , 2013, 2013 IEEE International Conference on Green Computing and Communications and IEEE Internet of Things and IEEE Cyber, Physical and Social Computing.

[71]  G. Tutz,et al.  An introduction to recursive partitioning: rationale, application, and characteristics of classification and regression trees, bagging, and random forests. , 2009, Psychological methods.

[72]  L. Khriji,et al.  Embedded gateway services for Internet of Things applications in ubiquitous healthcare , 2014, 2014 2nd International Conference on Information and Communication Technology (ICoICT).

[73]  Jianming Liu,et al.  Applications of Internet of Things on smart grid in China , 2011, 13th International Conference on Advanced Communication Technology (ICACT2011).

[74]  Waqas Hameed,et al.  Determining the factors associated with Unmet need for family planning: a cross-sectional survey in 49 districts of Pakistan , 2011 .

[75]  Ahmad-Reza Sadeghi,et al.  Securing the e-health cloud , 2010, IHI.

[76]  Khairul Anam,et al.  A Secured Cloud based Health Care Data Management System , 2012 .

[77]  Michele Ruta,et al.  CoAP-based healthcare sensor networks: A survey , 2014, Proceedings of 2014 11th International Bhurban Conference on Applied Sciences & Technology (IBCAST) Islamabad, Pakistan, 14th - 18th January, 2014.

[78]  Li-Xin Wang,et al.  The WM method completed: a flexible fuzzy system approach to data mining , 2003, IEEE Trans. Fuzzy Syst..

[79]  Manish Parashar,et al.  The analysis of image feature robustness using cometcloud , 2012, Journal of pathology informatics.

[80]  Changes in Health Care Financing and Organization Deriving Best Practice Models for the US Health Care Safety Net: A Cross-State Meta Analysis of Finance, Organization and Outcomes , 2003 .

[81]  Jeffrey E. Harris Fuchs' Who Shall Live? Health, Economics, and Social Choice , 1976 .

[82]  B. Walker I. Introduction , 2020 .

[83]  Ramjee Prasad,et al.  A cooperative Internet of Things (IoT) for rural healthcare monitoring and control , 2011, 2011 2nd International Conference on Wireless Communication, Vehicular Technology, Information Theory and Aerospace & Electronic Systems Technology (Wireless VITAE).

[84]  Zoltan Gal,et al.  eHealth solutions in the context of Internet of Things , 2014, 2014 IEEE International Conference on Automation, Quality and Testing, Robotics.

[85]  Vandana Pursnani Janeja,et al.  Predicting Hospital Length of Stay (PHLOS): A Multi-tiered Data Mining Approach , 2012, 2012 IEEE 12th International Conference on Data Mining Workshops.

[86]  J. V. Trapp,et al.  Radiotherapy Monte Carlo simulation using cloud computing technology , 2012, Australasian Physical & Engineering Sciences in Medicine.

[87]  Chris D. Nugent,et al.  Behavior Life Style Analysis for Mobile Sensory Data in Cloud Computing through MapReduce , 2014, Sensors.

[88]  Moneer Alam,et al.  Ageing, Socio-economic Disparities and Health Outcomes: Some Evidence from Rural India , 2009 .

[89]  Manuel de Buenaga Rodríguez,et al.  Integrating Internet of Things and Cloud Computing for Health Services Provisioning: The Virtual Cloud Carer Project , 2012, 2012 Sixth International Conference on Innovative Mobile and Internet Services in Ubiquitous Computing.

[90]  Ilias Maglogiannis,et al.  Mobile healthcare information management utilizing Cloud Computing and Android OS , 2010, 2010 Annual International Conference of the IEEE Engineering in Medicine and Biology.

[91]  Yu-Yi Chen,et al.  A Secure EHR System Based on Hybrid Clouds , 2012, Journal of Medical Systems.

[92]  Ruoyu Wu,et al.  Secure sharing of electronic health records in clouds , 2012, 8th International Conference on Collaborative Computing: Networking, Applications and Worksharing (CollaborateCom).

[93]  Robert S. H. Istepanian The potential of Internet of Things (IoT) for assisted living applications , 2011 .

[94]  R. Heltberg,et al.  Shocks, Coping, and Outcomes for Pakistan's Poor: Health Risks Predominate , 2008 .

[95]  M. Darianian,et al.  Smart Home Mobile RFID-Based Internet-of-Things Systems and Services , 2008, 2008 International Conference on Advanced Computer Theory and Engineering.

[96]  Nigel Collier,et al.  A framework for enhancing spatial and temporal granularity in report-based health surveillance systems , 2010, BMC Medical Informatics Decis. Mak..

[97]  Kyle Chard,et al.  A cloud-based approach to medical NLP. , 2011, AMIA ... Annual Symposium proceedings. AMIA Symposium.

[98]  Cem Ersoy,et al.  Wireless sensor networks for healthcare: A survey , 2010, Comput. Networks.

[99]  Luca Mainetti,et al.  Evolution of wireless sensor networks towards the Internet of Things: A survey , 2011, SoftCOM 2011, 19th International Conference on Software, Telecommunications and Computer Networks.

[100]  Muin J. Khoury,et al.  Application of support vector machine modeling for prediction of common diseases: the case of diabetes and pre-diabetes , 2010, BMC Medical Informatics Decis. Mak..

[101]  Pieter Van Gorp,et al.  Lifelong Personal Health Data and Application Software via Virtual Machines in the Cloud , 2014, IEEE Journal of Biomedical and Health Informatics.

[102]  Sylvain Arlot,et al.  A survey of cross-validation procedures for model selection , 2009, 0907.4728.

[103]  Shamsher Bahadur Patel,et al.  A Literature Review in Health Informatics Using Data Mining Techniques , 2014 .

[104]  Jerry M. Mendel,et al.  Linguistic summarization using IF-THEN rules , 2010, International Conference on Fuzzy Systems.

[105]  Pan Li,et al.  Towards auditable cloud-assisted access of encrypted health data , 2013, 2013 IEEE Conference on Communications and Network Security (CNS).

[106]  Lisandro Zambenedetti Granville,et al.  Internet of Things in healthcare: Interoperatibility and security issues , 2012, 2012 IEEE International Conference on Communications (ICC).

[107]  Birgitta Lindberg,et al.  Using Information and Communication Technology in Home Care for Communication between Patients, Family Members, and Healthcare Professionals: A Systematic Review , 2013, International journal of telemedicine and applications.

[108]  Sumeet Dua,et al.  Data Adaptive Rule-based Classification System for Alzheimer , 2013 .

[109]  Zhongtao Li,et al.  Artificial neural network models for prediction of cardiovascular autonomic dysfunction in general Chinese population , 2013, BMC Medical Informatics and Decision Making.

[110]  Dieter Hayn,et al.  The Internet of Things for Ambient Assisted Living , 2010, 2010 Seventh International Conference on Information Technology: New Generations.

[111]  Aparnaa Somanathan,et al.  Effect of payments for health care on poverty estimates in 11 countries in Asia: an analysis of household survey data , 2006, The Lancet.

[112]  H. Mcdonald,et al.  Effects of computerized clinical decision support systems on practitioner performance and patient outcomes: a systematic review. , 2005, JAMA.

[113]  Martha Ganser,et al.  A preliminary study of a cloud-computing model for chronic illness self-care support in an underdeveloped country. , 2011, American journal of preventive medicine.

[114]  Carmen C. Y. Poon,et al.  Big Data for Health , 2015, IEEE Journal of Biomedical and Health Informatics.

[115]  Oluwarotimi Williams Samuel,et al.  Enhanced Cloud based Model for Healthcare Delivery Organizations in Developing Countries , 2013 .

[116]  Antoine Bodin,et al.  Performance evaluation of a noninvasive hemoglobin monitoring device. , 2011, Annals of emergency medicine.

[117]  Marco Bazzani,et al.  Enabling the IoT Paradigm in E-health Solutions through the VIRTUS Middleware , 2012, 2012 IEEE 11th International Conference on Trust, Security and Privacy in Computing and Communications.

[118]  José Luís Oliveira,et al.  DICOM relay over the cloud , 2012, International Journal of Computer Assisted Radiology and Surgery.

[119]  Alexandre Santos,et al.  Internet of Things for Medication Control: E-Health Architecture and Service Implementation , 2013 .

[120]  Peter Szolovits Uncertainty and Decisions in Medical Informatics , 1995, Methods of Information in Medicine.

[121]  Victor I. Chang,et al.  A model to compare cloud and non-cloud storage of Big Data , 2016, Future Gener. Comput. Syst..

[122]  Randy H. Katz,et al.  A view of cloud computing , 2010, CACM.

[123]  Chao Li,et al.  SemanMedical: A kind of semantic medical monitoring system model based on the IoT sensors , 2012, 2012 IEEE 14th International Conference on e-Health Networking, Applications and Services (Healthcom).

[124]  X. Y Djam,et al.  A Fuzzy Expert System for the Management of Malaria , 2011 .

[125]  S. Nishtar,et al.  Pakistan's health system: performance and prospects after the 18th Constitutional Amendment , 2013, The Lancet.

[126]  Qiang Chen,et al.  A Health-IoT Platform Based on the Integration of Intelligent Packaging, Unobtrusive Bio-Sensor, and Intelligent Medicine Box , 2014, IEEE Transactions on Industrial Informatics.

[127]  Karthik Sundararaman,et al.  Dhatri - A Pervasive Cloud initiative for primary healthcare services , 2010, 2010 14th International Conference on Intelligence in Next Generation Networks.

[128]  Wan-Young Chung,et al.  Mobile Cloud-Computing-Based Healthcare Service by Noncontact ECG Monitoring , 2013, Sensors.

[129]  Sofiane Imadali,et al.  eHealth service support in IPv6 vehicular networks , 2012, 2012 IEEE 8th International Conference on Wireless and Mobile Computing, Networking and Communications (WiMob).

[130]  Hongming Cai,et al.  Ubiquitous Data Accessing Method in IoT-Based Information System for Emergency Medical Services , 2014, IEEE Transactions on Industrial Informatics.

[131]  F. Mekuria,et al.  Cloud Computing for Enhanced Mobile Health Applications , 2010, 2010 IEEE Second International Conference on Cloud Computing Technology and Science.

[132]  Kalai Anand Ratnam,et al.  Cloud services - Enhancing the Malaysian healthcare sector , 2012, 2012 International Conference on Computer & Information Science (ICCIS).

[133]  Hao Chen,et al.  Technical models and key technologies of E-Health Monitoring , 2012, 2012 IEEE 14th International Conference on e-Health Networking, Applications and Services (Healthcom).

[134]  Motohiro Nishimura,et al.  Development of the Regional EPR and PACS Sharing System on the Infrastructure of Cloud Computing Technology Controlled by Patient Identifier Cross Reference Manager , 2013, MedInfo.

[135]  Shaftab Ahmed,et al.  Tackling cloud security issues and forensics model , 2010, 7th International Symposium on High-capacity Optical Networks and Enabling Technologies.

[136]  J. Bryce,et al.  Measuring Coverage in MNCH: New Findings, New Strategies, and Recommendations for Action , 2013, PLoS medicine.

[137]  Chungui Liu,et al.  Community Medical Network (CMN): Architecture and implementation , 2011, 2011 Global Mobile Congress.

[138]  J. C. Dunn,et al.  A Fuzzy Relative of the ISODATA Process and Its Use in Detecting Compact Well-Separated Clusters , 1973 .

[139]  J Laufer,et al.  Secure Secondary Use of Clinical Data with Cloud-based NLP Services , 2014, Methods of Information in Medicine.

[140]  Borhanuddin Mohd Ali,et al.  A Network Mobility Solution Based on 6LoWPAN Hospital Wireless Sensor Network (NEMO-HWSN) , 2013, 2013 Seventh International Conference on Innovative Mobile and Internet Services in Ubiquitous Computing.

[141]  Hani Hagras,et al.  An Intelligent Fuzzy Agent Approach for Realising Ambient Intelligence in Intelligent Inhabited Environments , 2005 .

[142]  James L Robar,et al.  A Monte Carlo investigation of low-Z target image quality generated in a linear accelerator using Varian's VirtuaLinac. , 2014, Medical physics.

[143]  Peggy L. Peissig,et al.  Learning to Predict Post-Hospitalization VTE Risk from EHR Data , 2012, AMIA.

[144]  Igor Rudan,et al.  Care Seeking for Neonatal Illness in Low- and Middle-Income Countries: A Systematic Review , 2012, PLoS medicine.

[145]  Kashif Saeed,et al.  Rural Urban Food Consumption Analysis in Pakistan: Expenditure Elasticities Approach , 2015 .

[146]  Jiawei Han,et al.  Data Mining: Concepts and Techniques , 2000 .

[147]  V. Fuchs WHO SHALL LIVE? Health, Economics and Social Choice , 1976 .

[148]  Farid Kadri,et al.  PREDICTING HOSPITAL LENGTH OF STAY USING REGRESSION MODELS: APPLICATION TO EMERGENCY DEPARTMENT , 2014 .

[149]  David M Dror,et al.  Hardship financing of healthcare among rural poor in Orissa, India , 2011, BMC Health Services Research.

[150]  W. Hersh Medical informatics: improving health care through information. , 2002, JAMA.

[151]  Ilias Maglogiannis,et al.  Managing Wearable Sensor Data through Cloud Computing , 2011, 2011 IEEE Third International Conference on Cloud Computing Technology and Science.

[152]  Indrani Gupta and Deepa Sankar Health of the Elderly in India: A Multivariate Analysis , 2003 .

[153]  R. S. H. Istepanian,et al.  The potential of Internet of m-health Things “m-IoT” for non-invasive glucose level sensing , 2011, 2011 Annual International Conference of the IEEE Engineering in Medicine and Biology Society.

[154]  Leena Puustjärvi,et al.  Automating remote monitoring and information therapy: An opportunity to practice telemedicine in developing countries , 2011 .

[155]  Hans Schaffers,et al.  Smart Cities and the Future Internet: Towards Cooperation Frameworks for Open Innovation , 2011, Future Internet Assembly.

[156]  Adam Niewiadomski,et al.  A Type-2 Fuzzy Approach to Linguistic Summarization of Data , 2008, IEEE Transactions on Fuzzy Systems.

[157]  Chan Yeob Yeun,et al.  Framework of a national level electronic health record system , 2012, 2012 International Conference on Cloud Computing Technologies, Applications and Management (ICCCTAM).

[158]  Chinyao Low,et al.  Criteria for the Evaluation of a Cloud-Based Hospital Information System Outsourcing Provider , 2012, Journal of Medical Systems.

[159]  Ali Sunyaev,et al.  Privacy Engineering: Personal Health Records in Cloud Computing Environments , 2011, ICIS.

[160]  Vivek Ghosal,et al.  Adoption and Diffusion of Health Information Technology: The Case of Primary Care Clinics , 2012 .

[161]  Francisco Herrera,et al.  Interpretability of linguistic fuzzy rule-based systems: An overview of interpretability measures , 2011, Inf. Sci..

[162]  M. Baldwin,et al.  Gender Differences in Wage Losses from Impairments: Estimates from the Survey of Income and Program Participation , 1994 .

[163]  Yan Hu,et al.  A cloud computing solution for sharing healthcare information , 2012, 2012 International Conference for Internet Technology and Secured Transactions.

[164]  Ke Xu,et al.  Coping with out-of-pocket health payments: empirical evidence from 15 African countries. , 2008, Bulletin of the World Health Organization.

[165]  A. F. Chalmers,et al.  What Is This Thing Called Science , 1976 .

[166]  Rahat Iqbal,et al.  An intelligent framework for monitoring student performance using fuzzy rule-based Linguistic Summarisation , 2012, 2012 IEEE International Conference on Fuzzy Systems.

[167]  Rahat Iqbal,et al.  A fuzzy ambient intelligent agents approach for monitoring disease progression of dementia patients , 2012, Journal of Ambient Intelligence and Humanized Computing.

[168]  Lida Xu,et al.  IoT-Based Smart Rehabilitation System , 2014, IEEE Transactions on Industrial Informatics.

[169]  JeongGil Ko,et al.  Wireless Sensor Networks for Healthcare , 2010, Proceedings of the IEEE.

[170]  Ajay Mahal,et al.  Economic impacts of health shocks on households in low and middle income countries: a review of the literature , 2014, Globalization and Health.

[171]  Amit Kumar Manekar,et al.  Cloud Based Big Data Analytics a Review , 2015 .

[172]  Paul Watson,et al.  Developing cloud applications using the e-Science Central platform , 2013, Philosophical Transactions of the Royal Society A: Mathematical, Physical and Engineering Sciences.

[173]  Jimeng Sun,et al.  Big data analytics for healthcare , 2013, KDD.

[174]  Prashant Pandey,et al.  Cloud computing , 2010, ICWET.

[175]  Seymour Sudman,et al.  Measurement errors in surveys , 1993 .

[176]  Elizabeth Martin,et al.  METHODS FOR TESTING AND EVALUATING SURVEY QUESTIONS , 2004 .

[177]  Li Yang,et al.  Application of Internet of Things in the Community Security Management , 2011, 2011 Third International Conference on Computational Intelligence, Communication Systems and Networks.

[178]  Eugene J. Schweitzer,et al.  Reconciliation of the cloud computing model with US federal electronic health record regulations , 2012, J. Am. Medical Informatics Assoc..

[179]  Ling Liu,et al.  Security Models and Requirements for Healthcare Application Clouds , 2010, 2010 IEEE 3rd International Conference on Cloud Computing.

[180]  Weihua Wang,et al.  The internet of things for resident health information service platform research , 2011 .

[181]  J. Ross Quinlan,et al.  Simplifying Decision Trees , 1987, Int. J. Man Mach. Stud..

[182]  Nathaniel D Osgood,et al.  Selecting a dynamic simulation modeling method for health care delivery research-part 2: report of the ISPOR Dynamic Simulation Modeling Emerging Good Practices Task Force. , 2015, Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research.

[183]  Vittorio Miori,et al.  Anticipating Health Hazards through an Ontology-Based, IoT Domotic Environment , 2012, 2012 Sixth International Conference on Innovative Mobile and Internet Services in Ubiquitous Computing.

[184]  James P. Smith,et al.  Consequences and Predictors of New Health Events , 2003 .

[185]  James G. Anderson,et al.  Clearing the way for physicians' use of clinical information systems , 1997, CACM.

[186]  Joel L. Horowitz,et al.  Binary Response Models: Logits, Probits and Semiparametrics , 2001 .

[187]  L. Smircich,et al.  The Case for Qualitative Research , 1980 .

[188]  Eduardo Massad,et al.  Fuzzy Logic in Action: Applications in Epidemiology and Beyond , 2010, Studies in Fuzziness and Soft Computing.

[189]  Contributions from M. Walpole The Millennium Development Goals Report , 2008 .

[190]  Jianmin Wang,et al.  A cloud-based watermarking method for health data security , 2012, 2012 International Conference on High Performance Computing & Simulation (HPCS).

[191]  Hani Hagras,et al.  A fuzzy embedded agent-based approach for realizing ambient intelligence in intelligent inhabited environments , 2005, IEEE Transactions on Systems, Man, and Cybernetics - Part A: Systems and Humans.

[192]  Mark Atwood,et al.  Cost of venous thromboembolism in hospitalized medically ill patients. , 2006, American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists.

[193]  Ning Yang,et al.  A non-contact health monitoring model based on the Internet of things , 2012, 2012 8th International Conference on Natural Computation.

[194]  Todd H. Stokes,et al.  caREMOTE: The design of a cancer reporting and monitoring telemedicine system for domestic care , 2011, 2011 Annual International Conference of the IEEE Engineering in Medicine and Biology Society.

[195]  W. Kissick Medicine's Dilemmas: Infinite Needs versus Finite Resources , 1994 .

[196]  Tai-Hsi Wu,et al.  Using data mining techniques to predict hospitalization of hemodialysis patients , 2011, Decis. Support Syst..

[197]  Sania Nishtar,et al.  Choked pipes--reforming Pakistan's mixed health system. , 2010, JPMA. The Journal of the Pakistan Medical Association.

[198]  J. Mendel Uncertain Rule-Based Fuzzy Logic Systems: Introduction and New Directions , 2001 .

[199]  Adam Wagstaff,et al.  Catastrophe and impoverishment in paying for health care: with applications to Vietnam 1993-1998. , 2003, Health economics.

[200]  Eric C. Larson,et al.  SpiroSmart: using a microphone to measure lung function on a mobile phone , 2012, UbiComp.

[201]  Ondrej Topolcan,et al.  Monitoring of circulating tumor cells in patients undergoing surgery for hepatic metastases from colorectal cancer. , 2013, Anticancer research.

[202]  Antonio Iera,et al.  The Internet of Things: A survey , 2010, Comput. Networks.

[203]  Robert Ivor John,et al.  Computer aided fuzzy medical diagnosis , 2004, Inf. Sci..

[204]  Martin McKee,et al.  The contribution of health to the economy in the European Union. , 2006, Public health.

[205]  Rahat Iqbal,et al.  Type-2 fuzzy sets applied to multivariable self-organizing fuzzy logic controllers for regulating anesthesia , 2016, Appl. Soft Comput..

[206]  Vladimir Shusterman,et al.  Novel technical solutions for wireless ECG transmission & analysis in the age of the internet cloud. , 2013, Journal of electrocardiology.

[207]  André Calero Valdez,et al.  From cloud computing to mobile Internet, from user focus to culture and hedonism: The crucible of mobile health care and Wellness applications , 2010, 5th International Conference on Pervasive Computing and Applications.

[208]  Chia-Ping Shen,et al.  A Data-Mining Framework for Transnational Healthcare System , 2012, Journal of Medical Systems.

[209]  Hans-Ulrich Prokosch,et al.  Visions and strategies to improve evaluation of health information systems: Reflections and lessons based on the HIS-EVAL workshop in Innsbruck , 2004, Int. J. Medical Informatics.

[210]  Richard V. Burkhauser,et al.  The Economic Consequences of Disability , 1994 .

[211]  Qian Zhu,et al.  IOT Gateway: BridgingWireless Sensor Networks into Internet of Things , 2010, 2010 IEEE/IFIP International Conference on Embedded and Ubiquitous Computing.

[212]  Jinan Fiaidhi,et al.  Developing a Secure Distributed OSGi Cloud Computing Infrastructure for Sharing Health Records , 2011, AIS.

[213]  Doan B. Hoang,et al.  Novel Data Protection Model in Healthcare Cloud , 2011, 2011 IEEE International Conference on High Performance Computing and Communications.

[214]  Manas Ranjan Patra,et al.  CRHIS: cloud based rural healthcare information system , 2012, ICEGOV.

[215]  Manuel Rodríguez-Martínez,et al.  MedBook: A Cloud-Based Healthcare Billing and Record Management System , 2012, 2012 IEEE Fifth International Conference on Cloud Computing.

[216]  Bernadette Bouchon-Meunier,et al.  Fuzzy linguistic summaries: Where are we, where can we go? , 2012, 2012 IEEE Conference on Computational Intelligence for Financial Engineering & Economics (CIFEr).

[217]  S. Pal,et al.  Understanding Poverty among the Elderly in India: Implications for Social Pension Policy , 2011, SSRN Electronic Journal.

[218]  Steve G. Langer,et al.  Challenges for Data Storage in Medical Imaging Research , 2011, Journal of Digital Imaging.

[219]  I. Gronbaek Architecture for the Internet of Things (IoT): API and Interconnect , 2008, 2008 Second International Conference on Sensor Technologies and Applications (sensorcomm 2008).

[220]  Robert C. Amland,et al.  Clinical Decision Support for Early Recognition of Sepsis , 2014, American journal of medical quality : the official journal of the American College of Medical Quality.

[221]  Kimberly A. Neuendorf,et al.  The Content Analysis Guidebook , 2001 .

[222]  S. Nishtar,et al.  Health reform in Pakistan: a call to action , 2013, The Lancet.

[223]  Philip E. T. Lewis,et al.  Research Methods for Business Students , 2006 .

[224]  Rodrigo Roman,et al.  Securing the Internet of Things , 2017, Smart Cards, Tokens, Security and Applications, 2nd Ed..

[225]  Abdüsselam Altunkaynak,et al.  Water Consumption Prediction of Istanbul City by Using Fuzzy Logic Approach , 2005 .

[226]  Jie Huang,et al.  A Hierarchical Framework for Secure and Scalable EHR Sharing and Access Control in Multi-cloud , 2012, 2012 41st International Conference on Parallel Processing Workshops.

[227]  G. Vassilacopoulos,et al.  Ubiquitous access to cloud emergency medical services , 2010, Proceedings of the 10th IEEE International Conference on Information Technology and Applications in Biomedicine.

[228]  Viktor Mayer-Schnberger,et al.  Big Data: A Revolution That Will Transform How We Live, Work, and Think , 2013 .

[229]  J. Church Human Development Report , 2001 .