JPO1/CDCA7, a novel transcription factor E2F1-induced protein, possesses intrinsic transcriptional regulator activity.

[1]  C. Dang,et al.  The Myc target gene JPO1/CDCA7 is frequently overexpressed in human tumors and has limited transforming activity in vivo. , 2005, Cancer research.

[2]  C. Hawkins,et al.  Identification of a novel c-Myc protein interactor, JPO2, with transforming activity in medulloblastoma cells. , 2005, Cancer Research.

[3]  N. Dyson,et al.  The E2F transcriptional network: old acquaintances with new faces , 2005, Oncogene.

[4]  M. Kirschner,et al.  Sororin, a substrate of the anaphase-promoting complex, is required for sister chromatid cohesion in vertebrates. , 2005, Molecular cell.

[5]  S. Choi,et al.  R1, a Novel Repressor of the Human Monoamine Oxidase A* , 2005, Journal of Biological Chemistry.

[6]  K. Helin,et al.  The E2F family: specific functions and overlapping interests , 2004, The EMBO journal.

[7]  Ituro Inoue,et al.  Expression of MCM10 and TopBP1 is regulated by cell proliferation and UV irradiation via the E2F transcription factor , 2004, Oncogene.

[8]  William C Earnshaw,et al.  Borealin: a novel chromosomal passenger required for stability of the bipolar mitotic spindle. , 2004, The Journal of cell biology.

[9]  Ituro Inoue,et al.  Regulation of Geminin and Cdt1 expression by E2F transcription factors , 2004, Oncogene.

[10]  N. Dyson,et al.  Molecular mechanisms of E2F-dependent activation and pRB-mediated repression , 2004, Journal of Cell Science.

[11]  B. Aguda,et al.  A Structural Analysis of the Qualitative Networks Regulating the Cell Cycle and Apoptosis , 2003, Cell cycle.

[12]  H. Hermeking,et al.  The MYC oncogene as a cancer drug target. , 2003, Current cancer drug targets.

[13]  Itaru Matsumura,et al.  E2F1 and c-Myc in Cell Growth and Death , 2003, Cell cycle.

[14]  Chi V. Dang,et al.  A strategy for identifying transcription factor binding sites reveals two classes of genomic c-Myc target sites , 2003, Proceedings of the National Academy of Sciences of the United States of America.

[15]  N. L. La Thangue,et al.  E2F and cell cycle control: a double-edged sword. , 2003, Archives of biochemistry and biophysics.

[16]  S. Gygi,et al.  Tome-1, a Trigger of Mitotic Entry, Is Degraded during G1 via the APC , 2003, Cell.

[17]  H. Cam,et al.  Emerging roles for E2F: beyond the G1/S transition and DNA replication. , 2003, Cancer cell.

[18]  E. Salmon,et al.  hNuf2 inhibition blocks stable kinetochore–microtubule attachment and induces mitotic cell death in HeLa cells , 2002, The Journal of cell biology.

[19]  Stella Pelengaris,et al.  c-MYC: more than just a matter of life and death , 2002, Nature Reviews Cancer.

[20]  J. Bartek,et al.  E2F activity is essential for survival of Myc-overexpressing human cancer cells , 2002, Oncogene.

[21]  C. Albanese,et al.  E2F1 and c-Myc potentiate apoptosis through inhibition of NF-kappaB activity that facilitates MnSOD-mediated ROS elimination. , 2002, Molecular cell.

[22]  M. Eilers,et al.  Contributions of Myc to tumorigenesis. , 2002, Biochimica et biophysica acta.

[23]  C. Dang,et al.  A Novel c-Myc-responsive Gene, JPO1, Participates in Neoplastic Transformation* , 2001, The Journal of Biological Chemistry.

[24]  J. Cleveland,et al.  Bcl-2 is an apoptotic target suppressed by both c-Myc and E2F-1 , 2001, Oncogene.

[25]  M E Greenberg,et al.  Myc requires distinct E2F activities to induce S phase and apoptosis. , 2001, Molecular cell.

[26]  M. Walker.  Drug target discovery by gene expression analysis: cell cycle genes. , 2001, Current cancer drug targets.

[27]  J. Nevins,et al.  The Rb/E2F pathway and cancer. , 2001, Human molecular genetics.

[28]  J. Bartek,et al.  Pathways governing G1/S transition and their response to DNA damage , 2001, FEBS letters.

[29]  J. Harbour,et al.  The Rb/E2F pathway: expanding roles and emerging paradigms. , 2000, Genes & development.

[30]  N. Mailand,et al.  Involvement of Myc Activity in a G1/S-Promoting Mechanism Parallel to the pRb/E2F Pathway , 2000, Molecular and Cellular Biology.

[31]  K. Helin,et al.  CDC25A Phosphatase Is a Target of E2F and Is Required for Efficient E2F-Induced S Phase , 1999, Molecular and Cellular Biology.

[32]  J. Sedivy,et al.  Mysterious liaisons: the relationship between c-Myc and the cell cycle , 1999, Oncogene.

[33]  M. Cole,et al.  The Myc oncoprotein: a critical evaluation of transactivation and target gene regulation , 1999, Oncogene.

[34]  Chi V. Dang,et al.  c-Myc Target Genes Involved in Cell Growth, Apoptosis, and Metabolism , 1999, Molecular and Cellular Biology.

[35]  M. Cole,et al.  The Novel ATM-Related Protein TRRAP Is an Essential Cofactor for the c-Myc and E2F Oncoproteins , 1998, Cell.

[36]  N. Dyson.  The regulation of E2F by pRB-family proteins. , 1998, Genes & development.

[37]  J. Nevins,et al.  Toward an understanding of the functional complexity of the E2F and retinoblastoma families. , 1998, Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research.

[38]  B. Amati,et al.  Myc and the cell cycle. , 1998, Frontiers in bioscience : a journal and virtual library.

[39]  J. Nevins,et al.  Distinct roles for E2F proteins in cell growth control and apoptosis. , 1997, Proceedings of the National Academy of Sciences of the United States of America.

[40]  Andreas Sewing,et al.  Myc activation of cyclin E/Cdk2 kinase involves induction of cyclin E gene transcription and inhibition of p27Kip1 binding to newly formed complexes , 1997, Oncogene.

[41]  R. Eisenman,et al.  Myc target genes. , 1997, Trends in biochemical sciences.

[42]  D. Beach,et al.  Cdc25 cell-cycle phosphatase as a target of c-myc , 1996, Nature.

[43]  J. Bartek,et al.  Deregulated expression of E2F family members induces S-phase entry and overcomes p16INK4A-mediated growth suppression , 1996, Molecular and cellular biology.

[44]  J. Nevins,et al.  Regulation of the cyclin E gene by transcription factor E2F1. , 1995, Proceedings of the National Academy of Sciences of the United States of America.

[45]  W. Kaelin,et al.  Transcriptional control by E2F. , 1995, Seminars in cancer biology.

[46]  P. Silver,et al.  Nuf2, a spindle pole body-associated protein required for nuclear division in yeast , 1994, The Journal of cell biology.

[47]  J. Nevins,et al.  Expression of transcription factor E2F1 induces quiescent cells to enter S phase , 1993, Nature.

[48]  H. Weintraub,et al.  Sequence-specific DNA binding by the c-Myc protein. , 1990, Science.

[49]  Jeffrey M. Trimarchi,et al.  Transcription: Sibling rivalry in the E2F family , 2002, Nature Reviews Molecular Cell Biology.

[50]  R. Eisenman,et al.  The Myc/Max/Mad network and the transcriptional control of cell behavior. , 2000, Annual review of cell and developmental biology.

[51]  P. Farnham,et al.  Introduction to the E2F family: protein structure and gene regulation. , 1996, Current topics in microbiology and immunology.