Therapeutic potential of RNA interference.
暂无分享,去创建一个
[1] R. Bernards,et al. Stable suppression of tumorigenicity by virus-mediated RNA interference. , 2002, Cancer cell.
[2] S. Barik,et al. Phenotypic silencing of cytoplasmic genes using sequence-specific double-stranded short interfering RNA and its application in the reverse genetics of wild type negative-strand RNA viruses , 2001, BMC Microbiology.
[3] R. Plasterk,et al. Dicers at RISC The Mechanism of RNAi , 2004, Cell.
[4] C. Napoli,et al. Introduction of a Chimeric Chalcone Synthase Gene into Petunia Results in Reversible Co-Suppression of Homologous Genes in trans. , 1990, The Plant cell.
[5] M. Amarzguioui,et al. Positional effects of short interfering RNAs targeting the human coagulation trigger Tissue Factor. , 2002, Nucleic acids research.
[6] J. García,et al. Human influenza virus NS1 protein enhances viral pathogenicity and acts as an RNA silencing suppressor in plants. , 2004, The Journal of general virology.
[7] E. Ullu,et al. RNA interference in protozoan parasites , 2004, Cellular microbiology.
[8] B. Cullen,et al. Potent and Specific Inhibition of Human Immunodeficiency Virus Type 1 Replication by RNA Interference , 2002, Journal of Virology.
[9] Kaoru Saigo,et al. Short-Interfering-RNA-Mediated Gene Silencing in Mammalian Cells Requires Dicer and eIF2C Translation Initiation Factors , 2003, Current Biology.
[10] Wesley I. Sundquist,et al. Tsg101 and the Vacuolar Protein Sorting Pathway Are Essential for HIV-1 Budding , 2001, Cell.
[11] D. Dykxhoorn,et al. Killing the messenger: short RNAs that silence gene expression , 2003, Nature Reviews Molecular Cell Biology.
[12] H. Lage,et al. Modulation of the classical multidrug resistance (MDR) phenotype by RNA interference (RNAi) , 2003, FEBS letters.
[13] V. Ambros,et al. An Extensive Class of Small RNAs in Caenorhabditis elegans , 2001, Science.
[14] L. Lim,et al. An Abundant Class of Tiny RNAs with Probable Regulatory Roles in Caenorhabditis elegans , 2001, Science.
[15] T. Tuschl,et al. Identification of Novel Genes Coding for Small Expressed RNAs , 2001, Science.
[16] P. Zamore. Plant RNAi: How aViral Silencing Suppressor Inactivates siRNA , 2004, Current Biology.
[17] T. Tuschl,et al. Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells , 2001, Nature.
[18] Ali Ehsani,et al. Expression of small interfering RNAs targeted against HIV-1 rev transcripts in human cells , 2002, Nature Biotechnology.
[19] Shou-Wei Ding,et al. Interferon antagonist proteins of influenza and vaccinia viruses are suppressors of RNA silencing. , 2004, Proceedings of the National Academy of Sciences of the United States of America.
[20] R. Surabhi,et al. RNA Interference Directed against Viral and Cellular Targets Inhibits Human Immunodeficiency Virus Type 1 Replication , 2002, Journal of Virology.
[21] C. M. Owens,et al. The cytoplasmic body component TRIM5α restricts HIV-1 infection in Old World monkeys , 2004, Nature.
[22] F. Bushman,et al. Inhibition of Retroviral Pathogenesis by RNA Interference , 2002, Current Biology.
[23] A. Caudy,et al. Role for a bidentate ribonuclease in the initiation step of RNA interference , 2001 .
[24] J. Lieberman,et al. siRNA-directed inhibition of HIV-1 infection , 2002, Nature Medicine.
[25] Mario Stevenson,et al. Dissecting HIV-1 through RNA interference , 2003, Nature Reviews Immunology.
[26] M. Cornish,et al. A randomized controlled clinical trial of intravitreous fomivirsen for treatment of newly diagnosed peripheral cytomegalovirus retinitis in patients with AIDS. , 2002, American journal of ophthalmology.
[27] L. Verplank,et al. Tsg101, a homologue of ubiquitin-conjugating (E2) enzymes, binds the L domain in HIV type 1 Pr55Gag , 2001, Proceedings of the National Academy of Sciences of the United States of America.
[28] A. Ganser,et al. Specific inhibition of bcr-abl gene expression by small interfering RNA. , 2003, Blood.
[29] M. Manns,et al. Caspase 8 small interfering RNA prevents acute liver failure in mice , 2003, Proceedings of the National Academy of Sciences of the United States of America.
[30] S. Ding,et al. Induction and Suppression of RNA Silencing by an Animal Virus , 2002, Science.
[31] W. Dougherty,et al. Untranslatable transcripts of the tobacco etch virus coat protein gene sequence can interfere with tobacco etch virus replication in transgenic plants and protoplasts. , 1992, Virology.
[32] B. Cullen,et al. RNA interference in human cells is restricted to the cytoplasm. , 2002, RNA.
[33] A. Fire,et al. Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans , 1998, Nature.
[34] H. Vornlocher,et al. Inhibition of bcr-abl gene expression by small interfering RNA sensitizes for imatinib mesylate (STI571). , 2003, Blood.
[35] S. Hammond,et al. An RNA-directed nuclease mediates post-transcriptional gene silencing in Drosophila cells , 2000, Nature.
[36] A. Caudy,et al. Argonaute2, a Link Between Genetic and Biochemical Analyses of RNAi , 2001, Science.
[37] A. Borkhardt,et al. Killing of leukemic cells with a BCR/ABL fusion gene by RNA interference (RNAi) , 2002, Oncogene.
[38] E. Bucher,et al. The influenza A virus NS1 protein binds small interfering RNAs and suppresses RNA silencing in plants. , 2004, The Journal of general virology.
[39] D. Baulcombe,et al. Consistent gene silencing in transgenic plants expressing a replicating potato virus X RNA , 1997, The EMBO journal.
[40] Michael T. McManus,et al. Small Interfering RNA-Mediated Gene Silencing in T Lymphocytes1 , 2002, The Journal of Immunology.
[41] G. Hannon,et al. RNAi: an ever-growing puzzle. , 2003, Trends in biochemical sciences.
[42] Robert H. Silverman,et al. Activation of the interferon system by short-interfering RNAs , 2003, Nature Cell Biology.
[43] R. Iggo,et al. Induction of an interferon response by RNAi vectors in mammalian cells , 2003, Nature Genetics.
[44] T. Tuschl,et al. Functional anatomy of siRNAs for mediating efficient RNAi in Drosophila melanogaster embryo lysate , 2001, The EMBO journal.
[45] Judy Lieberman,et al. RNA interference targeting Fas protects mice from fulminant hepatitis , 2003, Nature Medicine.
[46] R. Andino,et al. Short interfering RNA confers intracellular antiviral immunity in human cells , 2002, Nature.
[47] K. Kemphues,et al. par-1, a gene required for establishing polarity in C. elegans embryos, encodes a putative Ser/Thr kinase that is asymmetrically distributed , 1995, Cell.