Computational Biology of Cancer: Lecture Notes and Mathematical Modeling

Cancer and Somatic Evolution Mathematical Modeling of Tumorigenesis Cancer Initiation: One-Hit and Two-Hit Stochastic Models Microsatellite and Chromosomal Istability in Sporadic and Familial Cancers Cellular Origins of Cancer Costs and Benefits of Chromosomal Instability DNA Damage and Genetic Instability Tissue Aging and the Development of Cancer Basic Models of Tumor Inhibition and Promotion Mechanisms of Tumor Neovascularization Cancer and Immune Responses Therapeutic Approaches: Viruses as Anti-Tumor Weapons