Transient airflow structures and particle transport in a sequentially branching lung airway model

Considering oscillatory laminar incompressible three-dimensional flow in triple planar and nonplanar bifurcations representing generations three to six of the human respiratory system, air flow fields and micron-particle transport have been simulated under normal breathing and high-frequency ventilation (HFV) conditions. A finite-volume code (CFX4.3 from AEA Technology, Pittsburgh, PA) and its user-enhanced FORTRAN programs were validated with experimental velocity data points for a single bifurcation. The airflow structures and micron-particle motion in the triple bifurcations were analyzed for a representative normal breathing cycle as well as HFV condition. While both the peak inspiratory and expiratory velocity profiles for the low Womersley case (α=0.93) agree well with those of instantaneously equivalent steady-state cases, some differences can be observed between flow acceleration and deceleration at off-peak periods or near flow reversal, especially during inspiratory flow. Similarly, the basic fe...

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