Financial and financial engineering considerations in supply chain and product development pipeline management

Enterprise-wide decision problems are receiving increasing attention in the process systems engineering literature. In particular, the supply chain and product development pipeline management components of this general class of problems have been subjects of intensive research in both their deterministic and their stochastic forms. The supply chain management (SCM) problem has seen work largely focused on the process operations and logistics components while for the product development pipeline management (PDPM) problem much of the attention has been on MILP formulations addressing the consequences of product failure during its development. In their full realization, both are recognized as challenging stochastic multi-stage decision problems. In this paper we discuss three important aspects of these problems that require further research: the realistic representation of the financial components and appropriate criteria for this class of problems, strategic management of supplier and customer relationships through inventory management and option contracts, and innovative approaches to suitably value and integrate a broader range of decisions available to management. We highlight and extend relevant contributions and case examples drawn from the recent literature that are emerging on these topics and use this work to point out further challenges.

[1]  Shannon P. Pratt,et al.  Cost of Capital: Estimation and Applications , 1998 .

[2]  Gintaras V. Reklaitis,et al.  A framework for addressing stochastic and combinatorial aspects of scheduling and resource allocation in pharmaceutical R&D pipelines , 2008, Comput. Chem. Eng..

[3]  Gintaras V. Reklaitis,et al.  Impact of tactical and operational policies in the selection of a new product portfolio , 2008, Comput. Chem. Eng..

[4]  Yair E. Orgler An Unequal-Period Model for Cash Management Decisions , 1969 .

[5]  G. Fandel,et al.  A general model for extended strategic supply chain management with emphasis on product life cycles including development and recycling , 2004 .

[6]  José Miguel Laínez,et al.  Capturing dynamics in integrated supply chain management , 2008, Comput. Chem. Eng..

[7]  Gintaras V. Reklaitis,et al.  Optimal design of batch‐storage network considering exchange rates and taxes , 2007 .

[8]  D. Teichroew,et al.  Optimal Short Term Financing Decision , 1965 .

[9]  Luis Puigjaner,et al.  Planning, scheduling and budgeting value-added chains , 2004, Comput. Chem. Eng..

[10]  William J. Baumol,et al.  The Transactions Demand for Cash: An Inventory Theoretic Approach , 1952 .

[11]  William S. Lovejoy,et al.  Quantity Flexibility Contracts and Supply Chain Performance , 1999, Manuf. Serv. Oper. Manag..

[12]  Yehuda Bassok,et al.  Analysis of supply contracts with commitments and flexibility , 2008 .

[13]  Lazaros G. Papageorgiou,et al.  A hierarchical solution approach for multi-site capacity planning under uncertainty in the pharmaceutical industry , 2004, Comput. Chem. Eng..

[14]  Vijayanand Subramanian A computational framework for studying decentralized supply chain dynamics , 2004 .

[15]  G. Reklaitis,et al.  A simulation based optimization approach to supply chain management under demand uncertainty , 2004, Comput. Chem. Eng..

[16]  N. Shah,et al.  Transfer Prices for Multienterprise Supply Chain Optimization , 2001 .

[17]  Christos T. Maravelias,et al.  A stochastic programming approach for clinical trial planning in new drug development , 2008, Comput. Chem. Eng..

[18]  Hau L. Lee,et al.  Material Management in Decentralized Supply Chains , 1993, Oper. Res..

[19]  J. Pekny,et al.  Managing a Portfolio of Interdependent New Product Candidates in the Pharmaceutical Industry , 2004 .

[20]  Gérard P. Cachon,et al.  Supply Chain Coordination with Revenue-Sharing Contracts: Strengths and Limitations , 2005, Manag. Sci..

[21]  J. Harsanyi Rational behavior and bargaining equilibrium in games and social situations: Frontmatter , 1977 .

[22]  Herbert E. Scarf,et al.  Optimal Policies for a Multi-Echelon Inventory Problem , 1960, Manag. Sci..

[23]  G. Guillén‐Gosálbez,et al.  Enhancing Corporate Value in the Optimal Design of Chemical Supply Chains , 2007 .

[24]  Cheng-Liang Chen,et al.  Multiobjective Optimization for a Multienterprise Supply Chain Network , 2003 .

[25]  Ravi Anupindi,et al.  Analysis of supply contracts with total minimum commitment , 1997 .

[26]  Merton H. Miller,et al.  A Model of the Demand for Money by Firms , 1966 .

[27]  Iftekhar A. Karimi,et al.  Planning in Pharmaceutical Supply Chains with Outsourcing and New Product Introductions , 2004 .

[28]  J. Nash THE BARGAINING PROBLEM , 1950, Classics in Game Theory.

[29]  Antonio Espuña Camarasa,et al.  Simultaneous optimization of process operations and financial decisions to enhance the integrated planning/scheduling of chemical supply chains , 2006, Comput. Chem. Eng..

[30]  Eugene M. Lerner Simulating a Cash Budget , 1968 .

[31]  Fredrik Weissenrieder,et al.  Value Based Management: Economic Value Added or Cash Value Added? , 1997 .

[32]  L. Puigjaner,et al.  Integrated on line production and financial scheduling with intelligent autonomous agent based information system , 1998 .

[33]  Paul Glasserman,et al.  Sensitivity Analysis for Base-Stock Levels in Multiechelon Production-Inventory Systems , 1995 .

[34]  N. Shah,et al.  Strategic Supply Chain Optimization for the Pharmaceutical Industries , 2001 .

[35]  Miller Upton,et al.  Introduction to Business Finance , 1953 .

[36]  Gintaras V. Reklaitis,et al.  Integrated safety stock management for multi-stage supply chains under production capacity constraints , 2008, Comput. Chem. Eng..

[37]  Sean P. Willems,et al.  Optimizing Strategic Safety Stock Placement in Supply Chains , 2000, Manuf. Serv. Oper. Manag..

[38]  Gintaras V. Reklaitis,et al.  Enterprise-wide modeling & optimization - An overview of emerging research challenges and opportunities , 2007, Comput. Chem. Eng..

[39]  V. Srinivasan,et al.  Deterministic cash flow management: State of the art and research directions , 1986 .

[40]  Juan Camilo Zapata,et al.  The multimode resource constrained multiproject scheduling problem: Alternative formulations , 2008 .

[41]  V. Srinivasan A Transshipment Model for Cash Management Decisions , 1974 .

[42]  I. Karimi,et al.  Regulatory Factors and Capacity-Expansion Planning in Global Chemical Supply Chains , 2004 .

[43]  Gintaras V. Reklaitis,et al.  Optimal design of batch‐storage network with financial transactions and cash flows , 2004 .

[44]  Evan L. Porteus,et al.  Chapter 7.( TGM) Supply Contracts with Quantity Commitments and Stochastic Demand by Ravi Annupindi & Yehuda Bassok Chapter 8. ( TGM) Supply Chain Contracting and Coordination with Stochastic Demand , 1996 .

[45]  I. Grossmann,et al.  Simultaneous Planning for New Product Development and Batch Manufacturing Facilities , 2001 .