The Ion Channel ASIC2 Is Required for Baroreceptor and Autonomic Control of the Circulation

[1]  A. Burden,et al.  Is Impaired Baroreflex Sensitivity a Predictor or Cause of Sudden Death in Insulin‐dependent Diabetes Mellitus? , 1997, Diabetic medicine : a journal of the British Diabetic Association.

[2]  F. Abboud,et al.  Differential Baroreflex Control of Heart Rate and Vascular Resistance in Rabbits: Relative Role of Carotid, Aortic, and Cardiopulmonary Baroreceptors , 1982, Circulation research.

[3]  A J Camm,et al.  Baroreflex Sensitivity and Heart Rate Variability in the Identification of Patients at Risk for Life-Threatening Arrhythmias: Implications for Clinical Trials , 2001, Circulation.

[4]  F Sachs,et al.  Stretch‐activated single ion channel currents in tissue‐cultured embryonic chick skeletal muscle. , 1984, The Journal of physiology.

[5]  T. Brennan,et al.  The mammalian sodium channel BNC1 is required for normal touch sensation , 2000, Nature.

[6]  M. Frischer,et al.  Sex surveys and drug users , 1993, Nature.

[7]  A Pedotti,et al.  Evaluation of baroreceptor reflex by blood pressure monitoring in unanesthetized cats. , 1988, The American journal of physiology.

[8]  M. Schaefer Homo- and heteromeric assembly of TRP channel subunits , 2005, Pflügers Archiv.

[9]  D. Benos,et al.  Heteromeric Assembly of Acid-sensitive Ion Channel and Epithelial Sodium Channel Subunits* , 2007, Journal of Biological Chemistry.

[10]  M. Welsh,et al.  Cloning and Expression of a Novel Human Brain Na Channel (*) , 1996, The Journal of Biological Chemistry.

[11]  M. Subramanyam,et al.  Regulation of the Epithelial Na+ Channel by Membrane Tension , 1998, The Journal of general physiology.

[12]  F. Abboud,et al.  The Prostacyclin Analogue Carbacyclin Inhibits Ca2+‐Activated K+ Current in Aortic Baroreceptor Neurones of Rats , 1997, The Journal of physiology.

[13]  Peter G. Gillespie,et al.  Molecular basis of mechanosensory transduction , 2001, Nature.

[14]  M. Lazdunski,et al.  ASIC2b-dependent Regulation of ASIC3, an Essential Acid-sensing Ion Channel Subunit in Sensory Neurons via the Partner Protein PICK-1* , 2004, Journal of Biological Chemistry.

[15]  E. Braunwald,et al.  Treatment of angina pectoris by electrical stimulation of the carotid-sinus nerves. , 1970, The New England journal of medicine.

[16]  H. Drummond,et al.  Degenerin/Epithelial Na+ Channel Proteins: Components of a Vascular Mechanosensor , 2004, Hypertension.

[17]  S. Landgren,et al.  On the excitation mechanism of the carotid baroceptors. , 1952, Acta physiologica Scandinavica.

[18]  F. Abboud,et al.  Impaired central mediation of the arterial baroreflex in chronic renal hypertension. , 1984, The American journal of physiology.

[19]  F. Abboud,et al.  Mechanosensitive currents in putative aortic baroreceptor neurons in vitro. , 1995, Journal of neurophysiology.

[20]  D. Clapham,et al.  TRP channels and mice deficient in TRP channels , 2005, Pflügers Archiv.

[21]  Andrew S. Wechsler,et al.  Relief of Angina Pectoris by Electrical Stimulation of the Carotid-Sinus Nerves , 1967 .

[22]  D. Cockayne,et al.  Acid‐sensing ion channels ASIC2 and ASIC3 do not contribute to mechanically activated currents in mammalian sensory neurones , 2004, The Journal of physiology.

[23]  Patricia A. Glazebrook,et al.  TRPC channels as signal transducers , 2005, Pflügers Archiv.

[24]  Miriam B Goodman,et al.  Transducing touch in Caenorhabditis elegans. , 2003, Annual review of physiology.

[25]  M. Chalfie,et al.  Degenerin similarities , 1993, Nature.

[26]  F. Abboud,et al.  Non-voltage-gated Ca2+ influx through mechanosensitive ion channels in aortic baroreceptor neurons. , 1997, Circulation research.

[27]  C HEYMANS,et al.  Reflexogenic Areas of the Cardiovascular System , 2015, Perspectives in biology and medicine.

[28]  M. Lazdunski,et al.  A proton-gated cation channel involved in acid-sensing , 1997, Nature.

[29]  Nektarios Tavernarakis,et al.  unc-8, a DEG/ENaC Family Member, Encodes a Subunit of a Candidate Mechanically Gated Channel That Modulates C. elegans Locomotion , 1997, Neuron.

[30]  M. Driscoll,et al.  Epithelial Na+ channels and stomatin are expressed in rat trigeminal mechanosensory neurons , 2000, Cell and Tissue Research.

[31]  J. Bigger,et al.  Baroreflex sensitivity and heart-rate variability in prediction of total cardiac mortality after myocardial infarction , 1998, The Lancet.

[32]  G. Gebhart,et al.  The Mechanosensitivity of Mouse Colon Afferent Fibers and Their Sensitization by Inflammatory Mediators Require Transient Receptor Potential Vanilloid 1 and Acid-Sensing Ion Channel 3 , 2005, The Journal of Neuroscience.

[33]  F. Abboud,et al.  Mechanical stimulation of neurites generates an inward current in putative aortic baroreceptor neurons in vitro , 1997, Brain Research.

[34]  Darrell R. Abernethy,et al.  International Union of Pharmacology: Approaches to the Nomenclature of Voltage-Gated Ion Channels , 2003, Pharmacological Reviews.

[35]  F. Abboud,et al.  A Molecular Component of the Arterial Baroreceptor Mechanotransducer , 1998, Neuron.

[36]  R. Iturriaga,et al.  Contribution of carotid body chemoreceptors and carotid sinus baroreceptors to the ventilatory and circulatory reflexes produced by common carotid occlusion. , 1988, Acta physiologica et pharmacologica latinoamericana : organo de la Asociacion Latinoamericana de Ciencias Fisiologicas y de la Asociacion Latinoamericana de Farmacologia.

[37]  F. Abboud,et al.  Arterial Baroreflexes in Renal Hypertensive Rabbits: Selectivity and Redundancy of Baroreceptor Influence on Heart Rate, Vascular Resistance, and Lumbar Sympathetic Nerve Activity , 1983, Circulation research.

[38]  R. Davisson,et al.  Long-term telemetric measurement of cardiovascular parameters in awake mice: a physiological genomics tool. , 2001, Physiological genomics.

[39]  M. Lazdunski,et al.  Knockout of the ASIC2 channel in mice does not impair cutaneous mechanosensation, visceral mechanonociception and hearing , 2004, The Journal of physiology.

[40]  M. Welsh,et al.  Heteromultimers of DEG/ENaC subunits form H+-gated channels in mouse sensory neurons , 2002, Proceedings of the National Academy of Sciences of the United States of America.

[41]  S. Sheng,et al.  Epithelial Na+ Channels Are Activated by Laminar Shear Stress* , 2004, Journal of Biological Chemistry.

[42]  Ronney B Panerai,et al.  Cardiac Baroreceptor Sensitivity Predicts Long-Term Outcome After Acute Ischemic Stroke , 2003, Stroke.

[43]  Craig Montell,et al.  International Union of Pharmacology. XLIII. Compendium of Voltage-Gated Ion Channels: Transient Receptor Potential Channels , 2003, Pharmacological Reviews.

[44]  J. Wemmie,et al.  Different contributions of ASIC channels 1a, 2, and 3 in gastrointestinal mechanosensory function , 2005, Gut.

[45]  D. Corey,et al.  Transport and Localization of the DEG/ENaC Ion Channel BNaC1α to Peripheral Mechanosensory Terminals of Dorsal Root Ganglia Neurons , 2001, The Journal of Neuroscience.

[46]  M. Chalfie,et al.  The MEC-4 DEG/ENaC channel of Caenorhabditis elegans touch receptor neurons transduces mechanical signals , 2005, Nature Neuroscience.

[47]  Stefan Heller,et al.  The mechanosensitive nature of TRPV channels , 2005, Pflügers Archiv.

[48]  Véronique Baudrie,et al.  Applicability of recent methods used to estimate spontaneous baroreflex sensitivity to resting mice. , 2008, American journal of physiology. Regulatory, integrative and comparative physiology.

[49]  M. Chalfie,et al.  The mec-4 gene is a member of a family of Caenorhabditis elegans genes that can mutate to induce neuronal degeneration , 1991, Nature.

[50]  F. Abboud,et al.  Mechano‐ and chemosensitivity of rat nodose neurones – selective excitatory effects of prostacyclin , 2007, The Journal of physiology.

[51]  Martin Chalfie,et al.  Gene interactions affecting mechanosensory transduction in Caenorhabditis elegans , 1994, Nature.

[52]  Masaru Sugimachi,et al.  Vagal Nerve Stimulation Markedly Improves Long-Term Survival After Chronic Heart Failure in Rats , 2003, Circulation.

[53]  F. Abboud,et al.  Gadolinium inhibits mechanoelectrical transduction in rabbit carotid baroreceptors. Implication of stretch-activated channels. , 1994, The Journal of clinical investigation.

[54]  E. Irwin,et al.  Chronic Baroreceptor Activation Enhances Survival in Dogs With Pacing-Induced Heart Failure , 2007, Hypertension.

[55]  F. Abboud,et al.  Arterial Baroreflexes in Renal Hypertensive Rabbits , 2005 .

[56]  D P Corey,et al.  Mechanosensation and the DEG/ENaC Ion Channels , 1996, Science.

[57]  J. Filippone,et al.  Baroreflex stimulation in the treatment of hypertension , 2007, Current opinion in nephrology and hypertension.

[58]  E. Braunwald,et al.  Treatment of Angina Pectoris by Electrical Stimulation of the Carotid-Sinus Nerves: Results in 17 Patients with Severe Angina , 1969 .

[59]  G D Pinna,et al.  Arterial baroreflex modulation of heart rate in chronic heart failure: clinical and hemodynamic correlates and prognostic implications. , 1997, Circulation.

[60]  John A Wemmie,et al.  Overexpression of acid-sensing ion channel 1a in transgenic mice increases acquired fear-related behavior. , 2004, Proceedings of the National Academy of Sciences of the United States of America.

[61]  F. Abboud,et al.  Analysis of afferent, central, and efferent components of the baroreceptor reflex in mice. , 2002, American journal of physiology. Regulatory, integrative and comparative physiology.