Diabetes induces fibrotic changes in the lung through the activation of TGF-β signaling pathways

[1]  G. Sethi,et al.  The Role of Signal Transducer and Activator of Transcription 3 (STAT3) and Its Targeted Inhibition in Hematological Malignancies , 2018, Cancers.

[2]  S. Mohammed,et al.  Impact of microRNA‐375 and its target gene SMAD‐7 polymorphism on susceptibility of colorectal cancer , 2018, Journal of clinical laboratory analysis.

[3]  Gang Liu,et al.  MiR-5100 targets TOB2 to drive epithelial-mesenchymal transition associated with activating smad2/3 in lung epithelial cells. , 2017, American journal of translational research.

[4]  E. Khairy,et al.  MicroRNA-181a and its target Smad 7 as potential biomarkers for tracking child acute lymphoblastic leukemia. , 2017, Gene.

[5]  Xiaofei Li,et al.  SIRT3 is correlated with the malignancy of non-small cell lung cancer. , 2017, International journal of oncology.

[6]  S. Lev,et al.  MicroRNA-182 targets SMAD7 to potentiate TGFβ-induced epithelial-mesenchymal transition and metastasis of cancer cells , 2016, Nature Communications.

[7]  J. Shieh,et al.  Lung damage induced by hyperglycemia in diabetic rats: The role of signal transducer and activator of transcription 3 (STAT3). , 2016, Journal of diabetes and its complications.

[8]  G. Hoyle,et al.  Diabetic Microvascular Disease and Pulmonary Fibrosis: The Contribution of Platelets and Systemic Inflammation , 2016, International journal of molecular sciences.

[9]  Tiehong Zhang,et al.  The Effect of Diabetes Mellitus on Lung Cancer Prognosis , 2016, Medicine.

[10]  G. Wolf,et al.  Epithelial-to-Mesenchymal Transition in Diabetic Nephropathy: Fact or Fiction? , 2015, Cells.

[11]  J. Pollack,et al.  SIRT7 inactivation reverses metastatic phenotypes in epithelial and mesenchymal tumors , 2015, Scientific Reports.

[12]  Jian He,et al.  Metformin and lung cancer risk of patients with type 2 diabetes mellitus: A meta-analysis. , 2015, Biomedical reports.

[13]  M. Galsky,et al.  Survival of patients with stage IV lung cancer with diabetes treated with metformin. , 2015, American journal of respiratory and critical care medicine.

[14]  G. Rogler,et al.  Hallmarks of epithelial to mesenchymal transition are detectable in Crohn’s disease associated intestinal fibrosis , 2015, Clinical and Translational Medicine.

[15]  Shiyue Li,et al.  Reduced risk of lung cancer with metformin therapy in diabetic patients: a systematic review and meta-analysis. , 2014, American journal of epidemiology.

[16]  L. Cai,et al.  Type 1 Diabetes Mellitus is an Independent Risk Factor for Pulmonary Fibrosis , 2014, Cell Biochemistry and Biophysics.

[17]  Samy Lamouille,et al.  Molecular mechanisms of epithelial–mesenchymal transition , 2014, Nature Reviews Molecular Cell Biology.

[18]  S. Spiegler,et al.  Alterations in lung gene expression in streptozotocin-induced diabetic rats , 2014, BMC Endocrine Disorders.

[19]  A. Rashad,et al.  Pulmonary function changes in diabetic lung , 2013 .

[20]  Sang Min Park,et al.  Diabetes mellitus as an independent risk factor for lung cancer: a meta-analysis of observational studies. , 2013, European journal of cancer.

[21]  Xilin Yang,et al.  Diabetes mellitus and incidence and mortality of kidney cancer: a meta-analysis. , 2013, Journal of diabetes and its complications.

[22]  M. Malek,et al.  Alteration of pulmonary function in diabetic nephropathy , 2013, Journal of Diabetes & Metabolic Disorders.

[23]  Sang Min Park,et al.  Diabetes Mellitus and Ovarian Cancer Risk: A Systematic Review and Meta-Analysis of Observational Studies , 2013, International Journal of Gynecologic Cancer.

[24]  C. Heldin,et al.  Regulation of EMT by TGFβ in cancer , 2012, FEBS letters.

[25]  M. Maggiolini,et al.  Caveolin-1 silencing arrests the proliferation of metastatic lung cancer cells through the inhibition of STAT3 signaling. , 2012, Cellular signalling.

[26]  T. Wynn,et al.  Mechanisms of fibrosis: therapeutic translation for fibrotic disease , 2012, Nature Medicine.

[27]  F. Zaccardi,et al.  The diabetic lung--a new target organ? , 2012, The review of diabetic studies : RDS.

[28]  L. Cai,et al.  Pulmonary fibrosis: a possible diabetic complication , 2011, Diabetes/metabolism research and reviews.

[29]  R. Kalluri,et al.  Mechanistic connection between inflammation and fibrosis. , 2010, Kidney international. Supplement.

[30]  Hong Li,et al.  Recombinant Decorin Ameliorates the Pulmonary Structure Alterations by Down-Regulating Transforming Growth Factor-β1/SMADS Signaling in the Diabetic Rats , 2010, Endocrine research.

[31]  A. Ferrara,et al.  Patients Diagnosed With Diabetes Are at Increased Risk for Asthma, Chronic Obstructive Pulmonary Disease, Pulmonary Fibrosis, and Pneumonia but Not Lung Cancer , 2009, Diabetes Care.

[32]  K. Reidy,et al.  Epithelial-mesenchymal transition and podocyte loss in diabetic kidney disease. , 2009, American journal of kidney diseases : the official journal of the National Kidney Foundation.

[33]  G. Wolf,et al.  TGF-beta and fibrosis in different organs - molecular pathway imprints. , 2009, Biochimica et biophysica acta.

[34]  Raghu Kalluri,et al.  The basics of epithelial-mesenchymal transition. , 2009, The Journal of clinical investigation.

[35]  Sun-Hee Park,et al.  HGF and BMP-7 ameliorate high glucose-induced epithelial-to-mesenchymal transition of peritoneal mesothelium. , 2009, Journal of the American Society of Nephrology : JASN.

[36]  Samy Lamouille,et al.  TGF-β-induced epithelial to mesenchymal transition , 2009, Cell Research.

[37]  S. Twigg,et al.  Fibrosis in diabetes complications: Pathogenic mechanisms and circulating and urinary markers , 2008, Vascular health and risk management.

[38]  F. Schmidt.  Meta-Analysis , 2008 .

[39]  A. Riggs,et al.  Genome-wide Analysis of Histone Lysine Methylation Variations Caused by Diabetic Conditions in Human Monocytes* , 2007, Journal of Biological Chemistry.

[40]  R. Richards,et al.  Isolation, biochemical characterization, and culture of lung type II cells of the rat , 2007, Lung.

[41]  Hang Yuan,et al.  Enhanced Proatherogenic Responses in Macrophages and Vascular Smooth Muscle Cells Derived From Diabetic db/db Mice , 2006, Diabetes.

[42]  M. Kasper,et al.  The use of alveolar epithelial type I cell-selective markers to investigate lung injury and repair , 2004, European Respiratory Journal.

[43]  D. Groneberg,et al.  SMAD-signaling in chronic obstructive pulmonary disease: transcriptional down-regulation of inhibitory SMAD 6 and 7 by cigarette smoke , 2004, Biological chemistry.

[44]  R. Kemler,et al.  E-cadherin is a survival factor for the lactating mouse mammary gland , 2002, Mechanisms of Development.

[45]  M. Bitzer,et al.  Transforming Growth Factor-β in Renal Disease , 1998, Kidney and Blood Pressure Research.

[46]  P. Haber,et al.  Pulmonary dysfunction in type 1 diabetes in relation to metabolic long-term control and to incipient diabetic nephropathy. , 1996, Nephron.

[47]  J. Barbosa,et al.  Effect of Kidney Dysfunction on Lung Volume in Patients With Diabetes , 1991, Diabetes Care.