The cortical excitability profile of temporal lobe epilepsy

Transcranial magnetic stimulation (TMS) was used to characterize measurable changes of cortical excitability in patients who were undergoing medical and surgical management of temporal lobe epilepsy (TLE) to investigate whether these alterations depended on timing of achieving seizure control throughout the course of illness and method of management.

[1]  Andreas Schulze-Bonhage,et al.  Changes in intracortical excitability after successful epilepsy surgery , 2008, Epilepsy Research.

[2]  Samuel Wiebe,et al.  Surgical outcomes in lesional and non-lesional epilepsy: A systematic review and meta-analysis , 2010, Epilepsy Research.

[3]  Jacob Cohen Statistical Power Analysis for the Behavioral Sciences , 1969, The SAGE Encyclopedia of Research Design.

[4]  L. Cohen,et al.  Reproducibility of intracortical inhibition and facilitation using the paired‐pulse paradigm , 2000, Muscle & nerve.

[5]  W. Oertel,et al.  Motor cortex excitability in focal epilepsies not including the primary motor area--a TMS study. , 2005, Brain : a journal of neurology.

[6]  Ulf Ziemann,et al.  TMS and drugs , 2004, Clinical Neurophysiology.

[7]  Á. Pascual-Leone,et al.  Inter- and intra-individual variability of paired-pulse curves with transcranial magnetic stimulation (TMS) , 2002, Clinical Neurophysiology.

[8]  P. Kwan,et al.  Early identification of refractory epilepsy. , 2000, The New England journal of medicine.

[9]  Graeme D. Jackson,et al.  Inter-session repeatability of cortical excitability measurements in patients with epilepsy , 2012, Epilepsy Research.

[10]  Graeme D. Jackson,et al.  Cortical excitability and Refractory epilepsy: a Three-Year longitudinal Transcranial Magnetic Stimulation Study , 2013, Int. J. Neural Syst..

[11]  K. Mills,et al.  Corticomotor threshold to magnetic stimulation: Normal values and repeatability , 1997, Muscle & nerve.

[12]  Mark Newton,et al.  Changes in cortical excitability differentiate generalized and focal epilepsy , 2007, Annals of neurology.

[13]  S. Wiebe,et al.  Epidemiology of Temporal Lobe Epilepsy , 2000, Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques.

[14]  P. Rossini,et al.  Non-invasive electrical and magnetic stimulation of the brain, spinal cord and roots: basic principles and procedures for routine clinical application. Report of an IFCN committee. , 1994, Electroencephalography and clinical neurophysiology.

[15]  S Noachtar,et al.  Motor cortex excitability in patients with focal epilepsy , 2000, Epilepsy Research.

[16]  Ulf Ziemann,et al.  Pharmacology of TMS. , 2003, Supplements to Clinical neurophysiology.

[17]  G. Migliaretti,et al.  Cortical Excitability in Cryptogenic Localization‐Related Epilepsy: Interictal Transcranial Magnetic Stimulation Studies , 2000, Epilepsia.

[18]  Ulf Ziemann,et al.  Chapter 23 Pharmacology of TMS , 2003 .

[19]  W. Löscher,et al.  The clinical impact of pharmacogenetics on the treatment of epilepsy , 2009, Epilepsia.

[20]  Babak Boroojerdi,et al.  Pharmacologic Influences on TMS Effects , 2002, Journal of clinical neurophysiology : official publication of the American Electroencephalographic Society.

[21]  R. C. Oldfield THE ASSESSMENT AND ANALYSIS OF HANDEDNESS , 1971 .

[22]  Ulf Ziemann,et al.  Inhibitory circuits and the nature of their interactions in the human motor cortex – a pharmacological TMS study , 2008, The Journal of physiology.

[23]  Samuel Wiebe,et al.  Long-term seizure outcomes following epilepsy surgery: a systematic review and meta-analysis. , 2005, Brain : a journal of neurology.

[24]  R. C. Oldfield The assessment and analysis of handedness: the Edinburgh inventory. , 1971, Neuropsychologia.

[25]  M. Fujiki,et al.  The relationship between paired pulse magnetic MEP and surgical prognosis in patients with intractable epilepsy , 2007, Seizure.

[26]  M. Brodie,et al.  Definition of drug resistant epilepsy: Consensus proposal by the ad hoc Task Force of the ILAE Commission on Therapeutic Strategies , 2011 .

[27]  A. Schulze-Bonhage,et al.  Changes in interhemispheric inhibition following successful epilepsy surgery: a TMS study , 2010, Journal of Neurology.