Small-conductance Ca2+-activated K+ channels: insights into their roles in cardiovascular disease

[1]  S. P. Oh,et al.  CXCL12-CXCR4 signalling plays an essential role in proper patterning of aortic arch and pulmonary arteries , 2017, Cardiovascular research.

[2]  J. Svendsen,et al.  Termination of Vernakalant-Resistant Atrial Fibrillation by Inhibition of Small-Conductance Ca2+-Activated K+ Channels in Pigs , 2017, Circulation. Arrhythmia and electrophysiology.

[3]  U. Ravens,et al.  Atrial fibrillation: Therapeutic potential of atrial K+ channel blockers. , 2017, Pharmacology & therapeutics.

[4]  Hannah A. Ledford,et al.  Distinct subcellular mechanisms for the enhancement of the surface membrane expression of SK2 channel by its interacting proteins, α‐actinin2 and filamin A , 2017, The Journal of physiology.

[5]  Tae Yun Kim,et al.  SK channel enhancers attenuate Ca2+-dependent arrhythmia in hypertrophic hearts by regulating mito-ROS-dependent oxidation and activity of RyR , 2017, Cardiovascular research.

[6]  T. Dieckmann,et al.  Structural Consequences of Calmodulin EF Hand Mutations. , 2017, Biochemistry.

[7]  M. Amalric,et al.  Changes in SK channel expression in the basal ganglia after partial nigrostriatal dopamine lesions in rats: Functional consequences , 2017, Neuropharmacology.

[8]  G. Thiel,et al.  The small neurotoxin apamin blocks not only small conductance Ca2+ activated K+ channels (SK type) but also the voltage dependent Kv1.3 channel , 2017, European Biophysics Journal.

[9]  G. Thiel,et al.  The small neurotoxin apamin blocks not only small conductance Ca2+ activated K+ channels (SK type) but also the voltage dependent Kv1.3 channel , 2017, European Biophysics Journal.

[10]  E. Lambe,et al.  Chronic social isolation reduces 5-HT neuronal activity via upregulated SK3 calcium-activated potassium channels , 2016, eLife.

[11]  H. Hashitani,et al.  Effects of K(+) channel openers on spontaneous action potentials in detrusor smooth muscle of the guinea-pig urinary bladder. , 2016, European journal of pharmacology.

[12]  T. Jespersen,et al.  Antiarrhythmic effect of the Ca2+-activated K+ (SK) channel inhibitor ICA combined with either amiodarone or dofetilide in an isolated heart model of atrial fibrillation , 2016, Pflügers Archiv - European Journal of Physiology.

[13]  Lia Crotti,et al.  Novel calmodulin mutations associated with congenital long QT syndrome affect calcium current in human cardiomyocytes. , 2016, Heart rhythm.

[14]  P. Barrett,et al.  Small-Conductance Ca2+-Activated Potassium Channels Negatively Regulate Aldosterone Secretion in Human Adrenocortical Cells , 2016, Hypertension.

[15]  Wen-Chin Tsai,et al.  Arrhythmogenic calmodulin mutations impede activation of small-conductance calcium-activated potassium current. , 2016, Heart rhythm.

[16]  Chi-Ling Chen,et al.  KCNN2 polymorphisms and cardiac tachyarrhythmias , 2016, Medicine.

[17]  Peng-Sheng Chen,et al.  Small conductance calcium-activated potassium current and the mechanism of atrial arrhythmia in mice with dysfunctional melanocyte-like cells. , 2016, Heart rhythm.

[18]  T. Jespersen,et al.  Antiarrhythmic effect of the Ca(2+)-activated K(+) (SK) channel inhibitor ICA combined with either amiodarone or dofetilide in an isolated heart model of atrial fibrillation , 2016 .

[19]  U. Sørensen,et al.  Role of Calcium-activated Potassium Channels in Atrial Fibrillation Pathophysiology and Therapy , 2015, Journal of cardiovascular pharmacology.

[20]  Junaid Kashir,et al.  Distinctive malfunctions of calmodulin mutations associated with heart RyR2-mediated arrhythmic disease. , 2015, Biochimica et biophysica acta.

[21]  Børge G Nordestgaard,et al.  P-wave duration and the risk of atrial fibrillation: Results from the Copenhagen ECG Study. , 2015, Heart rhythm.

[22]  W. Chazin,et al.  Arrhythmogenic Calmodulin Mutations Affect the Activation and Termination of Cardiac Ryanodine Receptor-mediated Ca2+ Release* , 2015, The Journal of Biological Chemistry.

[23]  T. Jespersen,et al.  Antiarrhythmic Mechanisms of SK Channel Inhibition in the Rat Atrium , 2015, Journal of cardiovascular pharmacology.

[24]  Po-Cheng Chang,et al.  SK channels and ventricular arrhythmias in heart failure. , 2015, Trends in cardiovascular medicine.

[25]  D. Lieu,et al.  Small-conductance Ca2+ -activated K+ channels and cardiac arrhythmias. , 2015, Heart rhythm.

[26]  T. Jespersen,et al.  Synergistic antiarrhythmic effect of combining inhibition of Ca²⁺-activated K⁺ (SK) channels and voltage-gated Na⁺ channels in an isolated heart model of atrial fibrillation. , 2015, Heart rhythm.

[27]  W. Shen,et al.  Down-regulation of the Small Conductance Calcium-activated Potassium Channels in Diabetic Mouse Atria* , 2015, The Journal of Biological Chemistry.

[28]  D. Lieu,et al.  Small-conductance Ca 2þ -activated K þ channels and cardiac arrhythmias , 2015 .

[29]  Jennifer Taylor Anatomical intelligence is helping cardiologists with interventions and diagnoses. , 2014, European heart journal.

[30]  Jennifer Taylor Leadless pacing debate: current issues in pacing. , 2014, European heart journal.

[31]  P. Binkley,et al.  Calcium-Activated Potassium Current Modulates Ventricular Repolarization in Chronic Heart Failure , 2014, PloS one.

[32]  S. Mahida Expanding role of SK channels in cardiac electrophysiology. , 2014, Heart rhythm.

[33]  Lei Yuan,et al.  Small-conductance calcium-activated potassium (SK) channels contribute to action potential repolarization in human atria. , 2014, Cardiovascular research.

[34]  V. Yarov-Yarovoy,et al.  Functional interaction with filamin A and intracellular Ca2+ enhance the surface membrane expression of a small-conductance Ca2+-activated K+ (SK2) channel , 2014, Proceedings of the National Academy of Sciences.

[35]  A. Feher,et al.  Age-related impairment of conducted dilation in human coronary arterioles. , 2014, American journal of physiology. Heart and circulatory physiology.

[36]  Peter J. Schwartz,et al.  Arrhythmogenic Calmodulin Mutations Disrupt Intracellular Cardiomyocyte Ca2+ Regulation by Distinct Mechanisms , 2014, Journal of the American Heart Association.

[37]  Niels Voigt,et al.  Cellular and Molecular Electrophysiology of Atrial Fibrillation Initiation, Maintenance, and Progression , 2014, Circulation research.

[38]  Stanley Nattel,et al.  The clinical profile and pathophysiology of atrial fibrillation: relationships among clinical features, epidemiology, and mechanisms. , 2014, Circulation research.

[39]  Qian Zhang,et al.  RyR2 Modulates a Ca2+-Activated K+ Current in Mouse Cardiac Myocytes , 2014, PloS one.

[40]  D. Terentyev,et al.  Sarcoplasmic reticulum Ca²⁺ release is both necessary and sufficient for SK channel activation in ventricular myocytes. , 2014, American journal of physiology. Heart and circulatory physiology.

[41]  Robert W. Mills,et al.  Overexpression of KCNN3 results in sudden cardiac death. , 2014, Cardiovascular research.

[42]  J. Weiss,et al.  Apamin‐Sensitive Calcium‐Activated Potassium Currents in Rabbit Ventricles with Chronic Myocardial Infarction , 2013, Journal of cardiovascular electrophysiology.

[43]  J. Weiss,et al.  Apamin induces early afterdepolarizations and torsades de pointes ventricular arrhythmia from failing rabbit ventricles exhibiting secondary rises in intracellular calcium. , 2013, Heart rhythm.

[44]  A. Ma,et al.  Bisoprolol reversed small conductance calcium-activated potassium channel (SK) remodeling in a volume-overload rat model , 2013, Molecular and Cellular Biochemistry.

[45]  J. Makielski,et al.  Channelopathies from mutations in the cardiac sodium channel protein complex. , 2013, Journal of molecular and cellular cardiology.

[46]  Jin Jen,et al.  Regulation of the SK3 channel by microRNA-499--potential role in atrial fibrillation. , 2013, Heart rhythm.

[47]  Jesper Hastrup Svendsen,et al.  J-shaped association between QTc interval duration and the risk of atrial fibrillation: results from the Copenhagen ECG study. , 2013, Journal of the American College of Cardiology.

[48]  Changyu Shen,et al.  Apamin-Sensitive Potassium Current Modulates Action Potential Duration Restitution and Arrhythmogenesis of Failing Rabbit Ventricles , 2013, Circulation. Arrhythmia and electrophysiology.

[49]  A. Gadicherla,et al.  Protection against cardiac injury by small Ca(2+)-sensitive K(+) channels identified in guinea pig cardiac inner mitochondrial membrane. , 2013, Biochimica et biophysica acta.

[50]  B. Nguyen,et al.  Heterogeneous Upregulation of Apamin‐Sensitive Potassium Currents in Failing Human Ventricles , 2013, Journal of the American Heart Association.

[51]  Po-Cheng Chang,et al.  Proarrhythmic effect of blocking the small conductance calcium activated potassium channel in isolated canine left atrium. , 2012, Heart rhythm.

[52]  Gregory A. Nelson,et al.  Functional Consequences of , 2013 .

[53]  D. Dobrev,et al.  New directions in antiarrhythmic drug therapy for atrial fibrillation. , 2013, Future cardiology.

[54]  P. Sah,et al.  Small-conductance Ca2+-activated K+ channels: form and function. , 2012, Annual review of physiology.

[55]  Dennis C Harrison Form and function , 2012, Canadian Medical Association Journal.

[56]  J. Weiss,et al.  Small-Conductance Calcium-Activated Potassium Channel and Recurrent Ventricular Fibrillation in Failing Rabbit Ventricles , 2010, Circulation research.

[57]  D. Jane,et al.  Small conductance calcium-activated potassium channels: From structure to function , 2010, Progress in Neurobiology.

[58]  Thomas Meitinger,et al.  Common Variants in KCNN3 are Associated with Lone Atrial Fibrillation , 2010, Nature Genetics.

[59]  Zhao Zhang,et al.  Ablation of a Ca2+‐activated K+ channel (SK2 channel) results in action potential prolongation in atrial myocytes and atrial fibrillation , 2009, The Journal of physiology.

[60]  Elisabetta Cerbai,et al.  Role of potassium currents in cardiac arrhythmias. , 2008, Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology.

[61]  Masanori Hirose,et al.  Early electrical remodeling in rabbit pulmonary vein results from trafficking of intracellular SK2 channels to membrane sites. , 2007, Cardiovascular research.

[62]  Ling Lu,et al.  Molecular Coupling of a Ca2+-Activated K+ Channel to L-Type Ca2+ Channels via α-Actinin2 , 2007 .

[63]  Ling Lu,et al.  Molecular coupling of a Ca2+-activated K+ channel to L-type Ca2+ channels via alpha-actinin2. , 2007, Circulation research.

[64]  Ling Lu,et al.  Molecular Coupling of a Ca 2-Activated K Channel to L-Type Ca 2 Channels via-Actinin 2 , 2006 .

[65]  Ling Lu,et al.  Differential expression of small-conductance Ca2+-activated K+ channels SK1, SK2, and SK3 in mouse atrial and ventricular myocytes. , 2005, American journal of physiology. Heart and circulatory physiology.

[66]  Yi Zhang,et al.  Molecular Identification and Functional Roles of a Ca2+-activated K+ Channel in Human and Mouse Hearts* , 2003, Journal of Biological Chemistry.

[67]  J. Adelman,et al.  Structure of the gating domain of a Ca2+-activated K+ channel complexed with Ca2+/calmodulin , 2001, Nature.