Nucleic acid structures and enzymes in the immunoglobulin class switch recombination mechanism.
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[1] A. Fischer,et al. Human uracil–DNA glycosylase deficiency associated with profoundly impaired immunoglobulin class-switch recombination , 2003, Nature Immunology.
[2] A. Fischer,et al. AID mutant analyses indicate requirement for class-switch-specific cofactors , 2003, Nature Immunology.
[3] M. Goodman,et al. Processive AID-catalysed cytosine deamination on single-stranded DNA simulates somatic hypermutation , 2003, Nature.
[4] A. Fischer,et al. Hyper-IgM syndrome type 4 with a B lymphocyte-intrinsic selective deficiency in Ig class-switch recombination. , 2003, The Journal of clinical investigation.
[5] A. Bhagwat,et al. Human activation-induced cytidine deaminase causes transcription-dependent, strand-biased C to U deaminations. , 2003, Nucleic acids research.
[6] F. Papavasiliou,et al. AID Mediates Hypermutation by Deaminating Single Stranded DNA , 2003, The Journal of experimental medicine.
[7] C. E. Schrader,et al. Mlh1 Can Function in Antibody Class Switch Recombination Independently of Msh2 , 2003, The Journal of experimental medicine.
[8] F. Alt,et al. The influence of transcriptional orientation on endogenous switch region function , 2003, Nature Immunology.
[9] M. Nussenzweig,et al. Transcription enhances AID-mediated cytidine deamination by exposing single-stranded DNA on the nontemplate strand , 2003, Nature Immunology.
[10] M. Lieber,et al. R-loops at immunoglobulin class switch regions in the chromosomes of stimulated B cells , 2003, Nature Immunology.
[11] F. Alt,et al. Transcription-targeted DNA deamination by the AID antibody diversification enzyme , 2003, Nature.
[12] M. Goodman,et al. Activation-induced cytidine deaminase deaminates deoxycytidine on single-stranded DNA but requires the action of RNase , 2003, Proceedings of the National Academy of Sciences of the United States of America.
[13] M. Radic,et al. DNA-dependent Protein Kinase Activity Is Not Required for Immunoglobulin Class Switching , 2002, The Journal of experimental medicine.
[14] D. Barnes,et al. Immunoglobulin Isotype Switching Is Inhibited and Somatic Hypermutation Perturbed in UNG-Deficient Mice , 2002, Current Biology.
[15] M. Neuberger,et al. Altering the pathway of immunoglobulin hypermutation by inhibiting uracil-DNA glycosylase , 2002, Nature.
[16] M. Neuberger,et al. AID mutates E. coli suggesting a DNA deamination mechanism for antibody diversification , 2002, Nature.
[17] F. Alt,et al. IgH class switch recombination to IgG1 in DNA-PKcs-deficient B cells. , 2002, Immunity.
[18] T. Honjo,et al. The AID enzyme induces class switch recombination in fibroblasts , 2002, Nature.
[19] M. Gellert. V(D)J recombination: RAG proteins, repair factors, and regulation. , 2002, Annual review of biochemistry.
[20] T. Honjo,et al. Quantitative Regulation of Class Switch Recombination by Switch Region Transcription , 2001, The Journal of experimental medicine.
[21] T. Honjo,et al. Palindromic but not G-rich sequences are targets of class switch recombination. , 2001, International immunology.
[22] U. Storb,et al. A Novel Cytidine Deaminase Affects Antibody Diversity , 2000, Cell.
[23] A. Fischer,et al. Activation-Induced Cytidine Deaminase (AID) Deficiency Causes the Autosomal Recessive Form of the Hyper-IgM Syndrome (HIGM2) , 2000, Cell.
[24] F. Alt,et al. Transcription-induced Cleavage of Immunoglobulin Switch Regions by Nucleotide Excision Repair Nucleases in Vitro* , 2000, The Journal of Biological Chemistry.
[25] T. Honjo,et al. Unique and unprecedented recombination mechanisms in class switching. , 2000, Current Opinion in Immunology.
[26] J. Stavnezer,et al. Switch recombination in a transfected plasmid occurs preferentially in a B cell line that undergoes switch recombination of its chromosomal Ig heavy chain genes. , 1999, Journal of immunology.
[27] R. Kucherlapati,et al. Reduced Isotype Switching in Splenic B Cells from Mice Deficient in Mismatch Repair Enzymes , 1999, The Journal of experimental medicine.
[28] T. Honjo,et al. Specific Expression of Activation-induced Cytidine Deaminase (AID), a Novel Member of the RNA-editing Deaminase Family in Germinal Center B Cells* , 1999, The Journal of Biological Chemistry.
[29] M. Neuberger,et al. Deficiency in Msh2 affects the efficiency and local sequence specificity of immunoglobulin class‐switch recombination: parallels with somatic hypermutation , 1999, The EMBO journal.
[30] N. Maizels,et al. G4 DNA Binding by LR1 and Its Subunits, Nucleolin and hnRNP D, A Role for G-G pairing in Immunoglobulin Switch Recombination* , 1999, The Journal of Biological Chemistry.
[31] Andreas Radbruch,et al. Processing of Switch Transcripts Is Required for Targeting of Antibody Class Switch Recombination , 1998, The Journal of experimental medicine.
[32] T. Honjo,et al. Target specificity of immunoglobulin class switch recombination is not determined by nucleotide sequences of S regions. , 1998, Immunity.
[33] Heikyung Suh,et al. Ku80 is required for immunoglobulin isotype switching , 1998, The EMBO journal.
[34] P. L. Bergsagel,et al. Promiscuous translocations into immunoglobulin heavy chain switch regions in multiple myeloma. , 1996, Proceedings of the National Academy of Sciences of the United States of America.
[35] A. Rolink,et al. The SCID but Not the RAG-2 Gene Product Is Required for Sμ–Sε Heavy Chain Class Switching , 1996 .
[36] M. Lieber,et al. Asymmetric mutation around the recombination break point of immunoglobulin class switch sequences on extrachromosomal substrates. , 1996, Nucleic acids research.
[37] J. Stavnezer. Antibody class switching. , 1996, Advances in immunology.
[38] Andreas Radbruch,et al. Switch transcripts in immunoglobulin class switching. , 1995, Science.
[39] T. Honjo,et al. Regulation of class switch recombination of the immunoglobulin heavy chain genes , 1995 .
[40] M. Lieber,et al. RNA:DNA complex formation upon transcription of immunoglobulin switch regions: implications for the mechanism and regulation of class switch recombination. , 1995, Nucleic acids research.
[41] R. Kumar,et al. Extrachromosomal eukaryotic DNA substrates for switch recombination: analysis of isotype and cell specificity. , 1994, DNA and cell biology.
[42] J. Lebowitz,et al. Transcription induces the formation of a stable RNA.DNA hybrid in the immunoglobulin alpha switch region. , 1994, The Journal of biological chemistry.
[43] F. Alt,et al. S region transcription per se promotes basal IgE class switch recombination but additional factors regulate the efficiency of the process. , 1994, The EMBO journal.
[44] N. Maizels,et al. Regulation and targeting of recombination in extrachromosomal substrates carrying immunoglobulin switch region sequences. , 1994, Molecular and cellular biology.
[45] F. Alt,et al. Replacement of germ-line epsilon promoter by gene targeting alters control of immunoglobulin heavy chain class switching. , 1993, Proceedings of the National Academy of Sciences of the United States of America.
[46] K. Rajewsky,et al. Shutdown of class switch recombination by deletion of a switch region control element , 1993, Science.
[47] G. Hertz,et al. DNA sequences at immunoglobulin switch region recombination sites. , 1993, Nucleic acids research.
[48] R. Coffman,et al. Mechanism and regulation of immunoglobulin isotype switching. , 1993, Advances in immunology.
[49] N. Maizels,et al. Transcriptional regulatory elements stimulate recombination in extrachromosomal substrates carrying immunoglobulin switch-region sequences. , 1992, Proceedings of the National Academy of Sciences of the United States of America.
[50] J. Stavnezer. Triple helix stabilization? , 1991, Nature.
[51] J. Griffin,et al. Induction of RNA-stabilized DMA conformers by transcription of an immunoglobulin switch region , 1990, Nature.
[52] H. Sakano,et al. Switch circular DNA formed in cytokine-treated mouse splenocytes: Evidence for intramolecular DNA deletion in immunoglobulin class switching , 1990, Cell.
[53] T. Honjo,et al. Circular DNA is excised by immunoglobulin class switch recombination , 1990, Cell.
[54] K. Marcu,et al. Molecular requirements for immunoglobulin heavy chain constant region gene switch-recombination revealed with switch-substrate retroviruses. , 1989, International immunology.
[55] Gritzmacher Ca. Molecular aspects of heavy-chain class switching. , 1989 .
[56] R. Wells,et al. Non-B right-handed DNA conformations of homopurine.homopyrimidine sequences in the murine immunoglobulin C alpha switch region. , 1988, The Journal of biological chemistry.
[57] F. Alt,et al. Structure and expression of germ line immunoglobulin gamma 2b transcripts , 1988, Molecular and cellular biology.
[58] F. Alt,et al. Immunoglobulin heavy chain switch region recombination within a retroviral vector in murine pre‐B cells. , 1987, The EMBO journal.
[59] F. Alt,et al. Secondary genomic rearrangement events in pre‐B cells: VHDJH replacement by a LINE‐1 sequence and directed class switching. , 1986, The EMBO journal.
[60] J. Petrini,et al. Complete nucleotide sequence of the murine gamma 3 switch region and analysis of switch recombination sites in two gamma 3-expressing hybridomas. , 1985, Journal of immunology.