Digital probes for three-dimensional microstructural analysis

The issue of function-property correlation studies in quantitative microstructure analysis is introduced. Modern digital stereological techniques are described and their role in such studies is discussed. Surface and volume estimation algorithms are presented in relation to the corresponding geometrical sampling probes utilized for analysis. The procedures are illustrated in both biomedical and metallurgical samples and the potential in further studies is discussed.

[1]  H. J. G. GUNDERSEN,et al.  Some new, simple and efficient stereological methods and their use in pathological research and diagnosis , 1988, APMIS : acta pathologica, microbiologica, et immunologica Scandinavica.

[2]  H. Gundersen,et al.  Stereological estimation of the volume‐weighted mean volume of arbitrary particles observed on random sections * , 1985, Journal of microscopy.

[3]  R. Fullman.  Measurement of Particle Sizes in Opaque Bodies , 1953 .

[4]  L M Cruz-Orive,et al.  Estimation of surface area from vertical sections , 1986, Journal of microscopy.

[5]  H. J. G. Gundersen,et al.  The impact of recent stereological advances on quantitative studies of the nervous system , 1986, Journal of Neuroscience Methods.

[6]  E B Hunziker,et al.  Stereology for anisotropic cells: Application to growth cartilage * , 1986, Journal of microscopy.

[7]  H J Gundersen,et al.  The efficiency of systematic sampling in stereology and its prediction * , 1987, Journal of microscopy.

[8]  石坂 昭三.  Science on form : 3D dynamic morphometry for bridge between structure and function : proceedings of the Second International Symposium for Science on Form, University of Tsukuba, Japan, October 19-21, 1988 , 1990 .

[9]  L. Santaló.  Integral geometry and geometric probability , 1976 .

[10]  H. J. G. Gundersen,et al.  The new stereological tools: Disector, fractionator, nucleator and point sampled intercepts and their use in pathological research and diagnosis , 1988, APMIS : acta pathologica, microbiologica, et immunologica Scandinavica.

[11]  E R Weibel,et al.  Measuring through the microscope: Development and evolution of stereological methods , 1989, Journal of microscopy.