Sinonasal cancer and exposure to styrene

We read with interest the recent article by Nissen et al ,1 which described a possible association of sinonasal adenocarcinoma with occupational exposure to styrene in the production of glass-reinforced plastics. Noting the limited statistical significance of their finding, and the potential for uncontrolled residual confounding by occupational exposure to wood dust, the authors called for further studies to confirm or refute the hazard. During the 1980s we …