Reducing Effect of IL-32α in the Development of Stroke Through Blocking of NF-κB, but Enhancement of STAT3 Pathways
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D. Yoon | J. Hong | Dong Hun Lee | Hyung-Mun Yun | S. Han | D. Choi | K. Oh | N. Y. Yoon | Y. Jung | Jin-Yi Han | C. J. Hwang | Hyun Ok Seo
[1] E. Isenovic,et al. Link Between Oxidative Stress and Acute Brain Ischemia , 2014, Angiology.
[2] A. Nadeem,et al. Glutathione modulation during sensitization as well as challenge phase regulates airway reactivity and inflammation in mouse model of allergic asthma. , 2014, Biochimie.
[3] F. Liu,et al. Propofol Protects Against Focal Cerebral Ischemia via Inhibition of Microglia-Mediated Proinflammatory Cytokines in a Rat Model of Experimental Stroke , 2013, PloS one.
[4] G. Marsicano,et al. Activation of STAT3 is involved in neuroprotection by electroacupuncture pretreatment via cannabinoid CB1 receptors in rats , 2013, Brain Research.
[5] Chunhua Zhu,et al. Parthenolide Is Neuroprotective in Rat Experimental Stroke Model: Downregulating NF-κB, Phospho-p38MAPK, and Caspase-1 and Ameliorating BBB Permeability , 2013, Mediators of inflammation.
[6] Jiumao Lin,et al. Electroacupuncture ameliorates cognitive impairment through inhibition of NF-κB-mediated neuronal cell apoptosis in cerebral ischemia-reperfusion injured rats. , 2013, Molecular medicine reports.
[7] G. Hu,et al. Paeoniflorin Protects against Ischemia-Induced Brain Damages in Rats via Inhibiting MAPKs/NF-κB-Mediated Inflammatory Responses , 2012, PloS one.
[8] H. Qiao,et al. Protective Effect of Luteolin in Experimental Ischemic Stroke: Upregulated SOD1, CAT, Bcl-2 and Claudin-5, Down-Regulated MDA and Bax Expression , 2012, Neurochemical Research.
[9] F. Islam,et al. Piperine suppresses cerebral ischemia–reperfusion-induced inflammation through the repression of COX-2, NOS-2, and NF-κB in middle cerebral artery occlusion rat model , 2012, Molecular and Cellular Biochemistry.
[10] R. Sultana,et al. Sex differences in brain proteomes of neuron‐specific STAT3‐null mice after cerebral ischemia/reperfusion , 2012, Journal of neurochemistry.
[11] L. Xiong,et al. Electroacupuncture Pretreatment as a Novel Avenue to Protect Brain against Ischemia and Reperfusion Injury , 2012, Evidence-based complementary and alternative medicine : eCAM.
[12] Xiaoling Zhang,et al. Luteolin downregulates TLR4, TLR5, NF-κB and p-p38MAPK expression, upregulates the p-ERK expression, and protects rat brains against focal ischemia , 2012, Brain Research.
[13] Gelin Xu,et al. Suppression of local inflammation contributes to the neuroprotective effect of ginsenoside Rb1 in rats with cerebral ischemia , 2012, Neuroscience.
[14] M. Beal,et al. Neuroprotective strategies involving ROS in Alzheimer disease. , 2011, Free radical biology & medicine.
[15] R. Giffard,et al. Astrocytes: targets for neuroprotection in stroke. , 2011, Central nervous system agents in medicinal chemistry.
[16] L. Xiong,et al. Reactive Oxygen Species Scavenger Inhibits STAT3 Activation After Transient Focal Cerebral Ischemia–Reperfusion Injury in Rats , 2011, Anesthesia and analgesia.
[17] H. J. Kim,et al. IL-32γ inhibits cancer cell growth through inactivation of NF-κB and STAT3 signals , 2011, Oncogene.
[18] R. Veerhuis. Histological and direct evidence for the role of complement in the neuroinflammation of AD. , 2011, Current Alzheimer research.
[19] C. Dinarello,et al. Paradoxical effects of constitutive human IL-32γ in transgenic mice during experimental colitis , 2010, Proceedings of the National Academy of Sciences.
[20] C. Rosen,et al. Age exaggerates proinflammatory cytokine signaling and truncates signal transducers and activators of transcription 3 signaling following ischemic stroke in the rat , 2010, Neuroscience.
[21] Wei Du,et al. Baicalein is neuroprotective in rat MCAO model: Role of 12/15-lipoxygenase, mitogen-activated protein kinase and cytosolic phospholipase A2 , 2010, Pharmacology Biochemistry and Behavior.
[22] G. Perry,et al. Oxidative stress in Alzheimer disease: A possibility for prevention , 2010, Neuropharmacology.
[23] Wei Du,et al. Tanshinone II A down-regulates HMGB1, RAGE, TLR4, NF-κB expression, ameliorates BBB permeability and endothelial cell function, and protects rat brains against focal ischemia , 2010, Brain Research.
[24] L. Edvinsson,et al. Cerebral ischemia induces microvascular pro-inflammatory cytokine expression via the MEK/ERK pathway , 2010, Journal of Neuroinflammation.
[25] V. Echeverria,et al. Sorafenib inhibits nuclear factor kappa B, decreases inducible nitric oxide synthase and cyclooxygenase-2 expression, and restores working memory in APPswe mice , 2009, Neuroscience.
[26] C. Kaltschmidt,et al. NF-kappaB in the nervous system. , 2009, Cold Spring Harbor perspectives in biology.
[27] D. Yoon,et al. A proinflammatory cytokine interleukin‐32β promotes the production of an anti‐inflammatory cytokine interleukin‐10 , 2009, Immunology.
[28] P. Vallet,et al. In vivo over‐expression of interleukin‐10 increases resistance to focal brain ischemia in mice , 2009, Journal of neurochemistry.
[29] Y. Liu,et al. Oxymatrine protects rat brains against permanent focal ischemia and downregulates NF-κB expression , 2009, Brain Research.
[30] Jongheop Yi,et al. Oxidative stress and apoptosis induced by titanium dioxide nanoparticles in cultured BEAS-2B cells. , 2008, Toxicology letters.
[31] Peng Huang,et al. Redox regulation of cell survival. , 2008, Antioxidants & redox signaling.
[32] S. Campbell,et al. Hepatic Nuclear Factor &kgr;B Regulates Neutrophil Recruitment to the Injured Brain , 2008, Journal of neuropathology and experimental neurology.
[33] Z. Qin,et al. Dual roles of NF-κB in cell survival and implications of NF-κB inhibitors in neuroprotective therapy , 2007, Acta Pharmacologica Sinica.
[34] S. Gerondakis,et al. Tissue-specific effects of the nuclear factor kappaB subunit p50 on myocardial ischemia-reperfusion injury. , 2007, The American journal of pathology.
[35] O. Rønnekleiv,et al. Role of Signal Transducer and Activator of Transcription-3 in Estradiol-Mediated Neuroprotection , 2007, The Journal of Neuroscience.
[36] N. Patel,et al. Inhibition of Aβ production by NF-κB inhibitors , 2007, Neuroscience Letters.
[37] M. Mattson,et al. NF-κB as a therapeutic target in neurodegenerative diseases , 2007 .
[38] Á. Chamorro,et al. Signalling pathways mediating inflammatory responses in brain ischaemia. , 2006, Biochemical Society transactions.
[39] A. Geronikaki,et al. Antioxidants and inflammatory disease: synthetic and natural antioxidants with anti-inflammatory activity. , 2006, Combinatorial chemistry & high throughput screening.
[40] David S. Park,et al. NFκB in neurons? The Uncertainty Principle in neurobiology , 2006 .
[41] M. Netea,et al. IL-32 synergizes with nucleotide oligomerization domain (NOD) 1 and NOD2 ligands for IL-1beta and IL-6 production through a caspase 1-dependent mechanism. , 2005, Proceedings of the National Academy of Sciences of the United States of America.
[42] C. Kaltschmidt,et al. Signaling via NF-?B in the nervous system , 2005 .
[43] R. Bolli,et al. Role of the Protein Kinase C-&egr;–Raf-1–MEK-1/2–p44/42 MAPK Signaling Cascade in the Activation of Signal Transducers and Activators of Transcription 1 and 3 and Induction of Cyclooxygenase-2 After Ischemic Preconditioning , 2005, Circulation.
[44] M. Moskowitz,et al. Neuroprotection by IL-10-producing MOG CD4+ T cells following ischemic stroke , 2005, Journal of the Neurological Sciences.
[45] N. Rothwell,et al. CNS injury: the role of the cytokine IL-1. , 2004, Veterinary journal.
[46] N. Greig,et al. Cholesterol and Alzheimer's disease: clinical and experimental models suggest interactions of different genetic, dietary and environmental risk factors. , 2004, Current drug targets.
[47] C. Sommer,et al. Effect of Brain-Derived Neurotrophic Factor Treatment and Forced Arm Use on Functional Motor Recovery After Small Cortical Ischemia , 2004, Stroke.
[48] M. Karjalainen‐Lindsberg,et al. Nuclear Factor- (cid:1) B Contributes to Infarction After Permanent Focal Ischemia , 2004 .
[49] Eng H. Lo,et al. Neurological diseases: Mechanisms, challenges and opportunities in stroke , 2003, Nature Reviews Neuroscience.
[50] T. Murphy,et al. Coordinate Regulation of Glutathione Biosynthesis and Release by Nrf2-Expressing Glia Potently Protects Neurons from Oxidative Stress , 2003, The Journal of Neuroscience.
[51] Gert Lubec,et al. Aberrant expression of peroxiredoxin subtypes in neurodegenerative disorders , 2003, Brain Research.
[52] B. Yoo,et al. Expression patterns of antioxidant proteins in brains of patients with sporadic Creutzfeldt‐Jacob disease , 2002, Electrophoresis.
[53] R. Bolli,et al. An essential role of the JAK-STAT pathway in ischemic preconditioning , 2001, Proceedings of the National Academy of Sciences of the United States of America.
[54] P. Chan. Reactive Oxygen Radicals in Signaling and Damage in the Ischemic Brain , 2001, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.
[55] S. Ghosh,et al. Molecular mechanisms of NF-κB activation induced by bacterial lipopolysaccharide through Toll-like receptors: , 2000 .
[56] E. Ongini,et al. Interleukin‐10 modulates neuronal threshold of vulnerability to ischaemic damage , 2000, The European journal of neuroscience.
[57] C. Justicia,et al. Activation of the JAK/STAT pathway following transient focal cerebral ischemia: Signaling through Jak1 and Stat3 in astrocytes , 2000, Glia.
[58] Haruo Okado,et al. Tumor Necrosis Factor Induces Bcl-2 and Bcl-x Expression through NFκB Activation in Primary Hippocampal Neurons* , 1999, The Journal of Biological Chemistry.
[59] R. Yezierski,et al. Traumatic Spinal Cord Injury Induces Nuclear Factor-κB Activation , 1998, The Journal of Neuroscience.
[60] Ulrich Dirnagl,et al. Increased Formation of Reactive Oxygen Species after Permanent and Reversible Middle Cerebral Artery Occlusion in the Rat , 1998, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.
[61] G. Benzi,et al. Are reactive oxygen species involved in Alzheimer's disease? , 1995, Neurobiology of Aging.
[62] D. Bredesen,et al. Bcl-2 inhibition of neural death: decreased generation of reactive oxygen species. , 1993, Science.
[63] J. Coyle,et al. Oxidative stress, glutamate, and neurodegenerative disorders. , 1993, Science.
[64] J. Adams,et al. Free radical induction in the brain and liver by products of toluene catabolism. , 1993, Biochemical pharmacology.
[65] S. Arbuck,et al. Taxol: the first of the taxanes, an important new class of antitumor agents. , 1992, Seminars in oncology.
[66] E. Hogan,et al. A model of focal ischemic stroke in the rat: reproducible extensive cortical infarction. , 1986, Stroke.
[67] Chen Chang,et al. Stroke, angiogenesis and phytochemicals. , 2012, Frontiers in bioscience.
[68] N. Alkayed,et al. Role of Signal Transducer and Activator of Transcription 3 in Neuronal Survival and Regeneration , 2008, Reviews in the neurosciences.
[69] N. Patel,et al. Inhibition of Abeta production by NF-kappaB inhibitors. , 2007, Neuroscience letters.
[70] M. Mattson,et al. NF-kappa B as a therapeutic target in neurodegenerative diseases. , 2007, Expert opinion on therapeutic targets.
[71] Z. Qin,et al. Dual roles of NF-kappaB in cell survival and implications of NF-kappaB inhibitors in neuroprotective therapy. , 2007, Acta pharmacologica Sinica.
[72] David S. Park,et al. NFkappaB in neurons? The uncertainty principle in neurobiology. , 2006, Journal of neurochemistry.
[73] D. Yoon,et al. Interleukin-32: a cytokine and inducer of TNFalpha. , 2005, Immunity.
[74] C. Kaltschmidt,et al. Signaling via NF-kappaB in the nervous system. , 2005, Biochimica et biophysica acta.
[75] C. Roussos,et al. Production of interleukin-6 by skeletal myotubes: role of reactive oxygen species. , 2002, American journal of respiratory cell and molecular biology.
[76] A. Martin-Villalba,et al. NF-kappaB is activated and promotes cell death in focal cerebral ischemia. , 1999, Nature medicine.
[77] R. Yezierski,et al. Traumatic spinal cord injury induces nuclear factor-kappaB activation. , 1998, The Journal of neuroscience : the official journal of the Society for Neuroscience.
[78] E. Hall,et al. Central nervous system trauma and stroke. II. Physiological and pharmacological evidence for involvement of oxygen radicals and lipid peroxidation. , 1989, Free radical biology & medicine.
[79] P. Weinstein,et al. Reversible middle cerebral artery occlusion without craniectomy in rats. , 1989, Stroke.