Evaluation of Blood Lactate Concentration in Dogs Receiving Whole Blood Transfusion

Background: A blood transfusion is a routine, life-saving procedure used to replace blood cells or blood products. The current study was aimed to assess whether the blood lactate concentration has a prognostic value of successful blood transfusion.Methods: During the period 2018-2019 group I dogs (n=19) received whole blood transfusion and twenty dogs were assigned to the control group (group II). Blood samples in group I were obtained from cephalic vein before blood transfusion (T0), then after it was finished (4hr±20 min) (T1) and 24hr±20 min after the T0 (T2).Result: The level of blood lactate reached the normal level after blood transfusion in T1 and T2. The clearance of lactate had a moderate negative correlation with packed cell volume (PCV) and red blood cells (RBC). There was no significant correlation between survival rate and blood lactate level. The survivals 24hr after transfusion (T2) had five times higher count of reticulocytes (RETIC) then non-survivals. Serial blood lactate measurement can improve the prediction of successful blood transfusion and it is useful in monitoring the patient status 24hr post blood transfusion, but it doesn’t have the predictive value of survival.

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