Urinary Microscopy as Seen by Nephrologists

Abstract Urinary microscopy is a diagnostic tool which is largely used by nephrologists. In the opinion of the authors the best results can be achieved when all the aspects concerning this test are properly taken into account. Thus, from the methodological point of view, proper patient guidance, proper urine collection and handling, adequate microscopic equipment, and knowledge of the factors which can influence the results are all necessary. All the elements of clinical importance have to be known, namely, erythrocytes (with their morphological subtypes), leukocytes, tubular cells, uroepithelial cells (both superficial and deep), lipids, casts, crystals, and microorganisms. Then, the urinary findings have to be interpreted and, whenever possible, also combined into urinary profiles (e.g., the nephritic sediment, the nephrotic sediment). This, combined with other laboratory tests, the pathologic findings, and the clinical data, allows for the definition and management of urinary tract diseases.

[1]  G. Fogazzi,et al.  Urine microscopic analysis--an art abandoned by nephrologists? , 1998, Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.

[2]  A. Dinda,et al.  Diagnosis of glomerular haematuria: role of dysmorphic red cell, G1 cell and bright-field microscopy. , 1997, Scandinavian journal of clinical and laboratory investigation.

[3]  L. Bonfante,et al.  Is the red cell morphology really useful to detect the source of hematuria? , 1997, American journal of nephrology.

[4]  G. Fogazzi,et al.  The erythrocyte cast. , 1996, Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.

[5]  G. Fogazzi Crystalluria: a neglected aspect of urinary sediment analysis. , 1996, Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.

[6]  C. Ponticelli,et al.  Microscopic hematuria diagnosis and management. , 1996, Nephron.

[7]  G. Pruneri,et al.  The cells of the deep layers of the urothelium in the urine sediment: an overlooked marker of severe diseases of the excretory urinary system. , 1995, Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.

[8]  J. Itoh,et al.  Differentiation of hematuria using a uniquely shaped red cell. , 1993, Nephron.

[9]  H. Köhler,et al.  Acanthocyturia--a characteristic marker for glomerular bleeding. , 1991, Kidney international.

[10]  C. Turner,et al.  Evaluation of light microscopy to localise the site of haematuria. , 1991, Archives of disease in childhood.

[11]  M. Georgopoulos,et al.  VALUE OF URINARY ERYTHROCYTE MORPHOLOGY IN ASSESSMENT OF SYMPTOMLESS MICROHAEMATURIA , 1989, The Lancet.

[12]  G. Braden,et al.  Urinary doubly refractile lipid bodies in nonglomerular renal diseases. , 1988, American journal of kidney diseases : the official journal of the National Kidney Foundation.

[13]  R. Hockberger,et al.  Hematuria induced by urethral catheterization. , 1987, Annals of emergency medicine.

[14]  N. D. De Santo,et al.  Phase contrast microscopy of the urine sediment for the diagnosis of glomerular and nonglomerular bleeding-data in children and adults with normal creatinine clearance. , 1987, Nephron.

[15]  M. Anger,et al.  Eosinophiluria--a new method of detection and definition of the clinical spectrum. , 1986, The New England journal of medicine.

[16]  L. Pead,et al.  A blind controlled trial of phase-contrast microscopy by two observers for evaluating the source of haematuria. , 1986, Nephron.

[17]  A. Sklar,et al.  Transmission electron microscopy of urinary sediment in human acute renal failure. , 1985, Kidney international.

[18]  F. Cuppage,et al.  Urinary lipid bodies in polycystic kidney disease. , 1985, American journal of kidney diseases : the official journal of the National Kidney Foundation.

[19]  G. Rizzoni,et al.  Evaluation of glomerular and nonglomerular hematuria by phase-contrast microscopy. , 1983, The Journal of pediatrics.

[20]  P. Kincaid‐smith Haematuria and exercise-related haematuria. , 1982, British medical journal.

[21]  R. Fassett,et al.  DETECTION OF GLOMERULAR BLEEDING BY PHASE-CONTRAST MICROSCOPY , 1982, The Lancet.

[22]  S. Fellner,et al.  Lymphocyturia: an important diagnostic and prognostic marker in renal allograft rejection. , 1982, American journal of nephrology.

[23]  K F Fairley,et al.  Hematuria: a simple method for identifying glomerular bleeding. , 1982, Kidney international.

[24]  C. Swartz,et al.  Clinically occult diffuse proliferative lupus nephritis. An age-related phenomenon. , 1979, Archives of internal medicine.

[25]  J. Klassen,et al.  Evolution of membranous nephropathy into anti-glomerular-basement-membrane glomerulonephritis. , 1974, The New England journal of medicine.

[26]  V. Pinn,et al.  Allergic interstitial nephritis causing reversible renal failure in four patients with idiopathic nephrotic syndrome. , 1973, The New England journal of medicine.

[27]  N. Carter,et al.  Acute glomerulonephritis with absence of abnormal urinary findings. Diagnosis by light and electron microscopy. , 1967, Annals of internal medicine.

[28]  J. Smith,et al.  Survival of urinary leucocytes , 1966, Journal of clinical pathology.

[29]  H GADEHOLT,et al.  Quantitative Estimation of Urinary Sediment, with Special Regard to Sources of Error , 1964, British medical journal.