Negative Impact of ST-Segment Elevation Myocardial Infarction and Morphine Dose on Ticagrelor Uptake and Pharmacodynamics: A Population PK/PD Analysis of Pooled Individual Participant Data
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[1] C. Haynes,et al. Characterization of the Presence and Function of Platelet Opioid Receptors , 2021, ACS measurement science Au.
[2] J. van der Linden,et al. Impact of morphine dose on ticagrelor uptake and platelet inhibition in patients with ST-segment elevation myocardial infarction – A substudy from the prospective randomized MOVEMENT trial , 2021, Thrombosis Update.
[3] Ò. Miró,et al. Antithrombotic and anticoagulation therapies in cardiogenic shock: a critical review of the published literature , 2021, ESC heart failure.
[4] K. Kubica,et al. Pharmacokinetic Modeling of Morphine’s Effect on Plasma Concentrations of Ticagrelor and Its Metabolite in Healthy Volunteers , 2021, Frontiers in Physiology.
[5] Ying Zhang,et al. Effects of morphine on P2Y12 platelet inhibitors in patients with acute myocardial infarction: A meta-analysis. , 2020, The American journal of emergency medicine.
[6] G. Filippatos,et al. Acute coronary syndromes and acute heart failure: a diagnostic dilemma and high‐risk combination. A statement from the Acute Heart Failure Committee of the Heart Failure Association of the European Society of Cardiology , 2020, European journal of heart failure.
[7] A. Harroche,et al. Real Life Population Pharmacokinetics Modelling of Eight Factors VIII in Patients with Severe Haemophilia A: Is It Always Relevant to Switch to an Extended Half-Life? , 2020, Pharmaceutics.
[8] J. Siller-Matula,et al. Impact of Preadmission Morphine on Reinfarction in Patients With ST‐Elevation Myocardial Infarction Treated With Percutaneous Coronary Intervention: A Meta‐Analysis , 2020, Clinical pharmacology and therapeutics.
[9] W. Chan,et al. Association of periprocedural intravenous morphine use on clinical outcomes in ST‐elevation myocardial infarction (STEMI) treated by primary percutaneous coronary intervention: Systematic review and meta‐analysis , 2020, Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions.
[10] E. Coomes,et al. Chewed or Crushed Administration of Adenosine Diphosphate Receptor Inhibitors in Acute Coronary Syndromes: a Systematic Review and Meta-analysis of Randomized Controlled Trials , 2019, Cardiovascular Drugs and Therapy.
[11] Hongwei Wu,et al. Prediction of Ticagrelor and its Active Metabolite in Liver Cirrhosis Populations Using a Physiologically Based Pharmacokinetic Model Involving Pharmacodynamics. , 2019, Journal of pharmaceutical sciences.
[12] M. Åstrand,et al. Population Pharmacokinetics/Pharmacodynamics of Ticagrelor in Children with Sickle Cell Disease , 2019, Clinical Pharmacokinetics.
[13] E. Navarese,et al. Determinants of high platelet reactivity in patients with acute coronary syndromes treated with ticagrelor , 2019, Scientific Reports.
[14] Abdur Rahman Khan,et al. Effect of morphine use on oral P2Y12 platelet inhibitors in acute myocardial infarction: Meta-analysis , 2019, Indian heart journal.
[15] G. Duarte,et al. Morphine in acute coronary syndrome: systematic review and meta-analysis , 2019, BMJ Open.
[16] Marc P. Bonaca,et al. Pharmacokinetic–pharmacodynamic modelling of platelet response to ticagrelor in stable coronary artery disease and prior myocardial infarction patients , 2018, British journal of clinical pharmacology.
[17] L. Been,et al. Effects of the Peripheral Opioid Receptor Antagonist Methylnaltrexone on the PK and PD Profiles of Ticagrelor in Patients With Coronary Artery Disease Treated With Morphine. , 2019, JACC. Cardiovascular interventions.
[18] M. Marszałł,et al. METoclopramide Administration as a Strategy to Overcome MORPHine-ticagrelOr Interaction in PatientS with Unstable Angina PectorIS—The METAMORPHOSIS Trial , 2018, Thrombosis and Haemostasis.
[19] Z. Djerada,et al. Alteration in the availability of epoxyeicosatrienoic acids contributes with NO to the development of endothelial dysfunction in conduit arteries during aging. , 2018, Atherosclerosis.
[20] B. Jilma,et al. Morphine Interaction with Aspirin: a Double-Blind, Crossover Trial in Healthy Volunteers , 2018, The Journal of Pharmacology and Experimental Therapeutics.
[21] X. Tian,et al. Population pharmacokinetics and pharmacodynamics of ticagrelor and AR-C124910XX in Chinese healthy male subjects , 2018, European Journal of Clinical Pharmacology.
[22] D. Guerrot,et al. Population Pharmacokinetic-Pharmacodynamic Modeling of Ropivacaine in Spinal Anesthesia , 2018, Clinical Pharmacokinetics.
[23] P. Kolh,et al. [2017 ESC focused update on dual antiplatelet therapy in coronary artery disease developed in collaboration with EACTS.] , 2018, Kardiologia polska.
[24] M. Marszałł,et al. Comparison of bioavailability and antiplatelet action of ticagrelor in patients with ST-elevation myocardial infarction and non-ST-elevation myocardial infarction: A prospective, observational, single-centre study , 2017, PloS one.
[25] J. van der Linden,et al. Ticagrelor pharmacokinetics and pharmacodynamics in patients with NSTEMI after a 180-mg loading dose , 2017, Platelets.
[26] Marc Lavielle,et al. Enhanced Method for Diagnosing Pharmacometric Models: Random Sampling from Conditional Distributions , 2016, Pharmaceutical Research.
[27] B. Jilma,et al. Morphine decreases ticagrelor concentrations but not its antiplatelet effects: a randomized trial in healthy volunteers , 2016, European journal of clinical investigation.
[28] M. Marszałł,et al. Morphine delays and attenuates ticagrelor exposure and action in patients with myocardial infarction: the randomized, double-blind, placebo-controlled IMPRESSION trial , 2015, European heart journal.
[29] D. Angiolillo,et al. Impact of Escalating Loading Dose Regimens of Ticagrelor in Patients With ST-Segment Elevation Myocardial Infarction Undergoing Primary Percutaneous Coronary Intervention: Results of a Prospective Randomized Pharmacokinetic and Pharmacodynamic Investigation. , 2015, JACC. Cardiovascular interventions.
[30] M. Price,et al. Bleeding and stent thrombosis on P2Y12-inhibitors: collaborative analysis on the role of platelet reactivity for risk stratification after percutaneous coronary intervention. , 2015, European heart journal.
[31] J. Dillinger,et al. Ticagrelor effectiveness overestimated by VASP index: platelet inhibition by ticagrelor versus prasugrel in acute coronary syndrome patients according to platelet function tests. , 2014, International journal of cardiology.
[32] P. Dobesh,et al. Ticagrelor: Pharmacokinetics, Pharmacodynamics, Clinical Efficacy, and Safety , 2014, Pharmacotherapy.
[33] Deepak L. Bhatt,et al. Consensus and update on the definition of on-treatment platelet reactivity to adenosine diphosphate associated with ischemia and bleeding. , 2013, Journal of the American College of Cardiology.
[34] R. Abbate,et al. Comparison of prasugrel and ticagrelor loading doses in ST-segment elevation myocardial infarction patients: RAPID (Rapid Activity of Platelet Inhibitor Drugs) primary PCI study. , 2013, Journal of the American College of Cardiology.
[35] F. Crea,et al. Evidence of increased platelet reactivity in the first six months after acute ST segment elevation myocardial infarction. , 2011, Thrombosis research.
[36] P. Gurbel,et al. The effect of ticagrelor versus clopidogrel on high on-treatment platelet reactivity: combined analysis of the ONSET/OFFSET and RESPOND studies. , 2011, American heart journal.
[37] S. Oliver,et al. Absorption, Distribution, Metabolism, and Excretion of Ticagrelor in Healthy Subjects , 2010, Drug Metabolism and Disposition.
[38] P. Holzer. Opioid receptors in the gastrointestinal tract , 2009, Regulatory Peptides.
[39] F. Verheugt,et al. Impaired bioavailability of clopidogrel in patients with a ST-segment elevation myocardial infarction. , 2008, Thrombosis research.
[40] C. Cannon,et al. Safety, tolerability, and initial efficacy of AZD6140, the first reversible oral adenosine diphosphate receptor antagonist, compared with clopidogrel, in patients with non-ST-segment elevation acute coronary syndrome: primary results of the DISPERSE-2 trial. , 2007, Journal of the American College of Cardiology.
[41] Mats O. Karlsson,et al. Implementation of a transit compartment model for describing drug absorption in pharmacokinetic studies , 2007, Journal of Pharmacokinetics and Pharmacodynamics.
[42] P. Tothill,et al. Inhibition of gastric emptying and drug absorption by narcotic analgesics. , 1975, British journal of clinical pharmacology.