Correlations of health behaviors and factors with high sensitivity C-reactive protein in diabetic population

Objective To explore the correlations of ideal cardiovascular health behaviors and factors with the level of high sensitivity C-reactive protein (hsCRP) in diabetic population. Methods A cross-sectional method was used in present study. Seven thousand eight hundred and sixty-nine workers with diabetes were recruited who participated in the 2006-2007 Kailuan health examination without history of cerebral and myocardial infarction and without data incompleted. All the information was obtained from the unified questionnaire and measurement of blood biochemistry. Multivariate logistic regression analysis was used to analyze the effects of ideal cardiovascular health behaviors and factors on the level of hsCRP. Results The hsCRP concentrations decreased with the increasing numbers of ideal cardiovascular health behaviors and factors, the medians of hsCRP concentrations were 1.16mg/L, 1.11mg/L, 0.90mg/L and 0.76mg/L in 0-1, 2, 3 and 4-6 ideal cardiovascular health groups, respectively (P<0.01). Multivariate logistic regression analysis showed that, after adjustment by age, gender, triglyceride, low density lipoprotein cholesterol (LDL-C) and high density lipoprotein cholesterol (HDL-C), the risk of hsCRP level exceeding 3mg/L in the subjects having 3 and 4-6 ideal cardiovascular health behaviors and factors was 0.60 times (95%CI 0.50-0.72) and 0.45 times (95%CI 0.34-0.61), respectively, than those having 0-1 ideal cardiovascular health behaviors and factors. Conclusion The hsCRP concentrations decreased with increasing numbers of ideal cardiovascular health behaviors and factors; the risk of hsCRP exceeding 3mg/L can be reduced by ideal cardiovascular health behaviors and factors. DOI: 10.11855/j.issn.0577-7402.2013.10.013

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