Analytical optical chromatography measurement of complex microparticles

A variation on the typical optical chromatography system was used to measure optical force differentials of complex micro-particles that have been assembled or fabricated using bead chemistries, bio-molecule tethers, or biological bead coatings. A number of bio-inspired particle types have been created to help elucidate the origin of optical force differentials that are known or suspected in biological systems such as bacterial cells / spores, and mammalian cells. A number of optical force measurements will be presented for a variety of micro-fabricated particles and the results and capabilities discussed.