Synaptic plasticity in a cerebellum-like structure depends on temporal order

WE report here the occurrence of somatic chromosome translocations in lymphocytes from individuals studied for clinical cytogenetic diagnosis. We note that these translocations are non-random in composition and resemble those in ataxia-telangiectasia (A-T) lymphocyte clones1. Our data have been collated with information from two other centres (Halifax and Atlanta) reported in this issue2,3 to provide a preliminary estimate of the frequency of chromosome translocations in cultured lymphocytes.

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