Codelivery of adavosertib and olaparib by tumor-targeting nanoparticles for augmented efficacy and reduced toxicity.
暂无分享,去创建一个
Li Zhang | Di Hu | Xu Qin | Chaoyang Sun | Gang Chen | Zifu Li | Junpeng Fan | Yuxuan Xiong | Bin Yang | Rourou Xiao | Funian Lu | Chen Liu | Yu Fu | Tianyu Qin | Ensong Guo | Wen Wang | Xing Hu | Yu Fu
[1] Rongjun Chen,et al. A Dendritic Polymer‐Based Nanosystem Mediates Drug Penetration and Irreversible Endoplasmic Reticulum Stresses in Tumor via Neighboring Effect , 2022, Advanced materials.
[2] Fei Li,et al. M11: A Tropism-modified Oncolytic Adenovirus Arming with Tumor-homing Peptide for Advanced Ovarian Cancer Therapies. , 2022, Human gene therapy.
[3] A. Jemal,et al. Cancer statistics, 2022 , 2022, CA: a cancer journal for clinicians.
[4] G. Mills,et al. WEE1 inhibition induces anti-tumor immunity by activating ERV and the dsRNA pathway , 2021, The Journal of experimental medicine.
[5] Lei Gu,et al. Branched Polymer‐Based Redox/Enzyme‐Activatable Photodynamic Nanoagent to Trigger STING‐Dependent Immune Responses for Enhanced Therapeutic Effect , 2021, Advanced Functional Materials.
[6] Lei Gu,et al. Stimuli‐Sensitive Linear–Dendritic Block Copolymer–Drug Prodrug as a Nanoplatform for Tumor Combination Therapy , 2021, Advanced materials.
[7] T. Yap,et al. Targeting the replication stress response through synthetic lethal strategies in cancer medicine. , 2021, Trends in cancer.
[8] G. Mills,et al. EFFORT: EFFicacy Of adavosertib in parp ResisTance: A randomized two-arm non-comparative phase II study of adavosertib with or without olaparib in women with PARP-resistant ovarian cancer. , 2021 .
[9] Xiangliang Yang,et al. Engineering nanomedicine for glutathione depletion-augmented cancer therapy. , 2021, Chemical Society reviews.
[10] Xiaoqi Dong,et al. Integration of Dual Targeting and Dual Therapeutic Modules Endows Self-Assembled Nanoparticles with Anti-Tumor Growth and Metastasis Functions , 2021, International journal of nanomedicine.
[11] Fulin Chen,et al. Elastin-like polypeptide modified silk fibroin porous scaffold promotes osteochondral repair , 2020, Bioactive materials.
[12] Zhuang Liu,et al. Tumor microenvironment-responsive intelligent nanoplatforms for cancer theranostics , 2020, Nano Today.
[13] Jinjin Zhang,et al. Cooperation therapy between anti-growth by photodynamic-AIEgens and anti-metastasis by small molecule inhibitors in ovarian cancer , 2020, Theranostics.
[14] K. Rostamizadeh,et al. In vivo study of poly (ethylene glycol)-poly (caprolactone)-modified folic acid nanocarriers as a pH responsive system for tumor-targeted co-delivery of tamoxifen and quercetin , 2019 .
[15] S. Heilshorn,et al. Rapid Diels-Alder Cross-linking of Cell Encapsulating Hydrogels. , 2019, Chemistry of materials : a publication of the American Chemical Society.
[16] G. Mills,et al. Sequential Therapy with PARP and WEE1 Inhibitors Minimizes Toxicity while Maintaining Efficacy. , 2019, Cancer cell.
[17] Peng Huang,et al. Mesoporous Polydopamine Carrying Manganese Carbonyl Responds to Tumor Microenvironment for Multimodal Imaging‐Guided Cancer Therapy , 2019, Advanced Functional Materials.
[18] Jing Wang,et al. Targeting DNA Damage Response Promotes Antitumor Immunity through STING-Mediated T-cell Activation in Small Cell Lung Cancer. , 2019, Cancer discovery.
[19] J. Schlenoff,et al. Engineering Thiolated Surfaces with Polyelectrolyte Multilayers. , 2019, ACS applied materials & interfaces.
[20] Yaou Duan,et al. Application of polydopamine in tumor targeted drug delivery system and its drug release behavior. , 2018, Journal of controlled release : official journal of the Controlled Release Society.
[21] J. Jalaei,et al. Antibacterial effects of gold nanoparticles functionalized with the extracted peptide from Vespa orientalis wasp venom , 2018, Journal of peptide science : an official publication of the European Peptide Society.
[22] G. Mills,et al. State-of-the-art strategies for targeting the DNA damage response in cancer , 2018, Nature Reviews Clinical Oncology.
[23] Gabe S. Sonke,et al. Maintenance Olaparib in Patients with Newly Diagnosed Advanced Ovarian Cancer , 2018, The New England journal of medicine.
[24] L. Shen,et al. Augmented antitumor activity by olaparib plus AZD1775 in gastric cancer through disrupting DNA damage repair pathways and DNA damage checkpoint , 2018, Journal of experimental & clinical cancer research : CR.
[25] Crispin J. Miller,et al. The Combination of the PARP Inhibitor Olaparib and the WEE1 Inhibitor AZD1775 as a New Therapeutic Option for Small Cell Lung Cancer , 2018, Clinical Cancer Research.
[26] R. Mrówczyński. Polydopamine-Based Multifunctional (Nano)materials for Cancer Therapy. , 2017, ACS applied materials & interfaces.
[27] S. Loi,et al. Olaparib for Metastatic Breast Cancer in Patients with a Germline BRCA Mutation. , 2017, The New England journal of medicine.
[28] T. Lawrence,et al. PARP1 Trapping and DNA Replication Stress Enhance Radiosensitization with Combined WEE1 and PARP Inhibitors , 2017, Molecular Cancer Research.
[29] H. K. Manjili,et al. Preparation and Characterization of PEGylated Iron Oxide-Gold Nanoparticles for Delivery of Sulforaphane and Curcumin , 2017, Drug Research.
[30] Feng Chen,et al. Mesoporous polydopamine nanoparticles with co-delivery function for overcoming multidrug resistance via synergistic chemo-photothermal therapy. , 2017, Nanoscale.
[31] A. Ashworth,et al. Modeling Therapy Resistance in BRCA1/2-Mutant Cancers , 2017, Molecular Cancer Therapeutics.
[32] J. Schellens,et al. Molecular Pathways: Targeting the Protein Kinase Wee1 in Cancer , 2017, Clinical Cancer Research.
[33] W. Haas,et al. Coupling of Homologous Recombination and the Checkpoint by ATR. , 2017, Molecular cell.
[34] Mark Morgan,et al. Targeting the ATR/CHK1 Axis with PARP Inhibition Results in Tumor Regression in BRCA-Mutant Ovarian Cancer Models , 2016, Clinical Cancer Research.
[35] A. Oza,et al. Phase I Study Evaluating WEE1 Inhibitor AZD1775 As Monotherapy and in Combination With Gemcitabine, Cisplatin, or Carboplatin in Patients With Advanced Solid Tumors. , 2016, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[36] G. Mills,et al. Establishment of Patient-Derived Tumor Xenograft Models of Epithelial Ovarian Cancer for Preclinical Evaluation of Novel Therapeutics , 2016, Clinical Cancer Research.
[37] X. Lou,et al. Formation of Asymmetric Bowl-Like Mesoporous Particles via Emulsion-Induced Interface Anisotropic Assembly. , 2016, Journal of the American Chemical Society.
[38] B. Karlan,et al. Characteristics of 10-year survivors of high-grade serous ovarian carcinoma. , 2016, Gynecologic oncology.
[39] Feng Chen,et al. Silica-assisted incorporation of polydopamine into the framework of porous nanocarriers by a facile one-pot synthesis. , 2016, Journal of materials chemistry. B.
[40] Jianru Xiao,et al. Multi-responsive photothermal-chemotherapy with drug-loaded melanin-like nanoparticles for synergetic tumor ablation. , 2016, Biomaterials.
[41] K. Cai,et al. Polydopamine Coatings in Confined Nanopore Space: Toward Improved Retention and Release of Hydrophilic Cargo , 2015 .
[42] Joshua M. Korn,et al. High-throughput screening using patient-derived tumor xenografts to predict clinical trial drug response , 2015, Nature Medicine.
[43] Wei Huang,et al. Engineering Melanin Nanoparticles as an Efficient Drug–Delivery System for Imaging‐Guided Chemotherapy , 2015, Advanced materials.
[44] Karen D. Cowden Dahl,et al. In vivo tumor growth of high-grade serous ovarian cancer cell lines. , 2015, Gynecologic oncology.
[45] Peter Gibbs,et al. Early detection of cancer: past, present, and future. , 2015, American Society of Clinical Oncology educational book. American Society of Clinical Oncology. Annual Meeting.
[46] Huimao Zhang,et al. Facile Preparation of Doxorubicin‐Loaded Upconversion@Polydopamine Nanoplatforms for Simultaneous In Vivo Multimodality Imaging and Chemophotothermal Synergistic Therapy , 2015, Advanced healthcare materials.
[47] Homan Kang,et al. Target-specific near-IR induced drug release and photothermal therapy with accumulated Au/Ag hollow nanoshells on pulmonary cancer cell membranes. , 2015, Biomaterials.
[48] Jörg Huwyler,et al. Nanomedicine in cancer therapy: challenges, opportunities, and clinical applications. , 2015, Journal of controlled release : official journal of the Controlled Release Society.
[49] N. Peppas,et al. Intelligent Nanoparticles for Advanced Drug Delivery in Cancer Treatment. , 2015, Current opinion in chemical engineering.
[50] V. A. Flørenes,et al. Wee1 is a novel independent prognostic marker of poor survival in post-chemotherapy ovarian carcinoma effusions. , 2014, Gynecologic oncology.
[51] D. Levine,et al. New Insights into PARP Inhibitors' Effect on Cell Cycle and Homology-Directed DNA Damage Repair , 2014, Molecular Cancer Therapeutics.
[52] Lehui Lu,et al. Polydopamine and its derivative materials: synthesis and promising applications in energy, environmental, and biomedical fields. , 2014, Chemical reviews.
[53] J. Ljubimova,et al. Nanomedicine therapeutic approaches to overcome cancer drug resistance. , 2013, Advanced drug delivery reviews.
[54] Jian Ji,et al. Mussel-inspired polydopamine: a biocompatible and ultrastable coating for nanoparticles in vivo. , 2013, ACS nano.
[55] Won Jong Kim,et al. Photothermally triggered cytosolic drug delivery via endosome disruption using a functionalized reduced graphene oxide. , 2013, ACS nano.
[56] C. Sander,et al. Evaluating cell lines as tumour models by comparison of genomic profiles , 2013, Nature Communications.
[57] Andreas Wicki,et al. Tolerability, safety, pharmacokinetics, and efficacy of doxorubicin-loaded anti-EGFR immunoliposomes in advanced solid tumours: a phase 1 dose-escalation study. , 2012, The Lancet. Oncology.
[58] Tsuyoshi Arai,et al. Small-molecule inhibition of Wee1 kinase by MK-1775 selectively sensitizes p53-deficient tumor cells to DNA-damaging agents , 2009, Molecular Cancer Therapeutics.
[59] R. Chen,et al. TMTP1, a Novel Tumor-Homing Peptide Specifically Targeting Metastasis , 2008, Clinical Cancer Research.
[60] Lei Tao,et al. Design and synthesis of N-maleimido-functionalized hydrophilic polymers via copper-mediated living radical polymerization: a suitable alternative to PEGylation chemistry. , 2005, Journal of the American Chemical Society.
[61] H. Maeda,et al. Tumor vascular permeability and the EPR effect in macromolecular therapeutics: a review. , 2000, Journal of controlled release : official journal of the Controlled Release Society.