Studies on uracils: A facile one-pot synthesis of pyrazolo[3,4-d]pyrimidines

The reaction of 6-hydrazino uracils 1 and nitrones 2 result in an efficient one-pot synthesis of pyrazolo[3,4-d]pyrimidines 3 in excellent yields. The isolation of the by-product aniline from the reaction mixture supported the plausible mechanism for the formation of pyrazolo[3,4-d]pyrimidines.

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