The thalassaemia syndromes

Authors and Contributors. Preface to the Fourth Edition. Preface to the First Edition. Acknowledgements. Part 1 Historical Background.1. Historical Perspectives: The Many and Diverse Routes to our Current Understanding of the Thalassaemia Syndromes. Part 2 The Biology of The Thalassaemias. 2. Human Haemoglobin 3. Thalassaemia: Classification and Relationship to Other Inherited Diseases of Haemoglobin.4. The Molecular Pathology of the Thalassaemias. 5. Pathophysiology of the Thalassaemias. 6. The World Distribution and Population Genetics of Thalassaemia. Part 3 Clinical Features of the Thalassaemias 7. The beta Thalassaemias.8. The delta beta and Related Thalassaemias 9. The beta and delta beta Thalassaemia in Association with Structural Haemoglobin Variants.10. Hereditary Persistence of Fetal Haemoglobin.11. The alpha Thalassaemias and Their Interactions with Structural Haemoglobin Variants. 12. Thalassaemia withmental retardation or Myelodysplasia. 13. Thalassaemia Intermedia. Part 4 Diagnosis and management of thalassaemia. 14. Avoidance and Population Control.15. Management and prognosis.16. Laboratory Diagnosis of the Thalassaemias. Part 5 The Future. References. Appendix. Index.